Düzeltme:
THE DECISIVE ROLE OF SHOCK INDEX IN FLUID THERAPY IN HEMORRHAGIC TRAUMA CASES IN EMS: A RETROSPECTIVE STUDY
Yıl 2023,
Cilt: 8 Sayı: 3, 294 - 307, 03.01.2024
Ali Ekşi
,
Sevgi Öztürk Günay
Süreyya Gümüşsoy
,
Yusuf Ali Altuncı
,
Funda Karbek Akarca
Öz
Aim: The study aimed to evaluate the determining role of the shock index (SI) in initiating fluid therapy in trauma patients with active bleeding in out-of-hospital emergency care.
Method: Trauma patients aged 18 years and older with active bleeding who were brought to the emergency department of a university hospital between 01.07.2010 and 01.07.2020 were scanned. A total of 3367 patients’ files were scanned, and 587 of them who met the inclusion criteria were included in the study. The patients' shock indexes (SI) were calculated based on the first measured vital signs in the EMS ambulance. The SPSS was used for statistical analysis. The chi-square test was used to determine the relationship between the independent and dependent variables. The results were evaluated at a confidence interval of 95%, and p <0.05 was accepted as statistically significant
Results: It was found that >500 mL IV crystalloid fluid was administered to 76.7% of the patients at out-of-hospital, 66.4% (n=390) had hemorrhagic shock according to the out-of-hospital SI, 60.3% had a systolic blood pressure of >90 mmHg at the first measurement. Out-of-hospital SI averages of those who died in the hospital were higher than those who were discharged. It was found that among the patients who did not have shock according to the SI, those who received out-of-hospital IV fluids had a higher hospital death rate.
Conclusion: SI can be used as a tool for out-of-hospital trauma patient identification and mortality assessment. SI can be used as a predictive tool in determining the need for out-of-hospital fluid therapy.
Kaynakça
- Berger, T, Green, J, Horeczko, T, Hagar, Y, Garg, N, Suarez, A, Panacek, E, & Shapiro, N. (2013). Shock index and early recognition of sepsis in the Emergency Department: Pilot study. Western Journal of Emergency Medicine, 14(2). https://doi.org/10.5811/westjem.2012.8.11546.
- Birkhahn, RH, Gaeta, TJ, Terry, D, Bove, JJ, & Tloczkowski, J. (2005). Shock index in diagnosing early acute hypovolemia. American Journal of Emergency Medicine, 23(3). https://doi.org/10.1016/j.ajem.2005.02.029.
Björkman, J, Raatiniemi, L, Setälä, P., Nurmi, J. (2021). Shock index as a predictor for short-term mortality in helicopter emergency medical services: A registry study. Acta Anaesthesiologica Scandinavica, 65(6). https://doi.org/10.1111/aas.13765.
- Bores, SA, Pajerowski, W, Carr, BG, Holena, D, Meisel, ZF, Mechem, CC, Band, RA. (2018). The Association of Prehospital Intravenous Fluids and Mortality in Patients with Penetrating Trauma. Journal of Emergency Medicine, 54(4). https://doi.org/10.1016/j.jemermed.2017.12.046.
- Bourque, JS-C, Cliche, J, Chauny, J, Daoust, R, Paquet, J, Piette, É. (2013). Accuracy of the shock index and various modified shock indexes to predict early mortality in patients suffering from gastrointestinal haemorrhage. Critical Care, 17(S2). https://doi.org/10.1186/cc12157.
- Cannon, CM, Braxton, CC, Kling-Smith, M, Mahnken, JD, Carlton, E, Moncure, M. (2009). Utility of the shock index in predicting mortality in traumatically injured patients. Journal of Trauma - Injury, Infection and Critical Care, 67(6). https://doi.org/10.1097/TA.0b013e3181bbf728.
- Cannon, JW, Khan, MA, Raja, AS, Cohen, MJ, Como, JJ, Cotton, BA, Dubose, JJ, Fox, EE, Inaba, K, Rodriguez, CJ, Holcomb, JB, Duchesne, JC. (2017). Damage control resuscitation in patients with severe traumatic hemorrhage: A practice management guideline from the Eastern Association for the Surgery of Trauma. Journal of Trauma and Acute Care Surgery, 82(3). https://doi.org/10.1097/TA.0000000000001333.
- Chen, CH, Shin, S Do, Sun, JT, Jamaluddin, SF, Tanaka, H, Song, KJ, Kajino, K, Kimura, A, Huang, EPC, Hsieh, MJ, Ma, MHM., Chiang, WC. (2020). Association between prehospital time and outcome of trauma patients in 4 Asian countries: A cross-national, multicenter cohort study. PLoS Medicine, 17(10). https://doi.org/10.1371/journal.pmed.1003360.
- Duchesne, JC, Kimonis, K, Marr, AB, Rennie, KV, Wahl, G, Wells, JE, Islam, TM, Meade, P, Stuke, L, Barbeau, JM, Hunt, JP, Baker, CC, McSwain, NE. (2010). Damage control resuscitation in combination with damage control laparotomy: A survival advantage. Journal of Trauma - Injury, Infection and Critical Care, 69(1). https://doi.org/10.1097/TA.0b013e3181df91fa.
- Dula, DJ, Wood, GC, Rejmer, AR, Starr, M, Leicht, M. (2002). U SE OF P REHOSPITAL F LUIDS IN H YPOTENSIVE B LUNT T RAUMA P ATIENTS. Prehospital Emergency Care, 6(4), 417–420.
- Dutton, RP, Mackenzie, CF, Scalea, TM. (2002). Hypotensive resuscitation during active hemorrhage; impact on in-hospital mortality. Journal of Trauma, 52(6). https://doi.org/10.1097/00005373-200206000-00020.
- Erol, G, Aytaç, İ, Güven Aytaç, B. (2021). Do shock index, modified shock index, and shock index by age have a predictive value in determining the risk of post-spinal hypotension in elderly patients? Turk Geriatri Dergisi, 24(3). https://doi.org/10.31086/tjgeri.2021.233.
- Geeraedts, LMG, Pothof, LAH, Caldwell, E, De Lange-De Klerk, ESM., D’Amours, SK. (2015). Prehospital fluid resuscitation in hypotensive trauma patients: Do we need a tailored approach? Injury, 46(1). https://doi.org/10.1016/j.injury.2014.08.001.
- Hampton, DA, Fabricant, LJ, Differding, J, Diggs, B, Underwood, S, De La Cruz, D, … et al (2013). Prehospital intravenous fluid is associated with increased survival in trauma patients. Journal of Trauma and Acute Care Surgery, 75(1 SUPPL1). https://doi.org/10.1097/TA.0b013e318290cd52.
- Haut, ER, Kalish, BT, Cotton, BA, Efron, DT, Haider, AH, Stevens, KA, … et al 011). Prehospital intravenous fluid administration is associated with higher mortality in trauma patients: A national trauma data bank analysis. Annals of Surgery, 253(2). https://doi.org/10.1097/SLA.0b013e318207c24f.
- Katayama, Y., Kitamura, T., Kiyohara, K., Ishida, K., Hirose, T., Nakao, S., … et al (2022). Effect of fluid administration on scene to traffic accident patients by EMS personnel: a propensity score-matched study using population-based ambulance records and nationwide trauma registry in Japan. European Journal of Trauma and Emergency Surgery, 48(2). https://doi.org/10.1007/s00068-020-01590-z.
- Kauvar, DS, Lefering, R, Wade, CE. (2006). Impact of hemorrhage on trauma outcome: An overview of epidemiology, clinical presentations, and therapeutic considerations. Journal of Trauma - Injury, Infection and Critical Care, 60(6 SUPPL.). https://doi.org/10.1097/01.ta.0000199961.02677.19.
- Kim, DK, Jeong, J, Shin, S Do, Song, KJ, Hong, KJ, Ro, YS, Kim, TH, … et al(2021). Association between prehospital field to emergency department delta shock index and in-hospital mortality in patients with torso and extremity trauma: A multinational, observational study. PLoS ONE, 16(10 October). https://doi.org/10.1371/journal.pone.0258811.
- Kudo, D, Yoshida, Y, Kushimoto, S. (2017). Permissive hypotension/hypotensive resuscitation and restricted/controlled resuscitation in patients with severe trauma. In Journal of Intensive Care (Vol. 5, Issue 1). https://doi.org/10.1186/s40560-016-0202-z.
- Liu, Y, Liu, J, Fang, ZA, Shan, G, Xu, J, Qi, Z, … et al (2012). Modified shock index and mortality rate of emergency patients. World Journal of Emergency Medicine, 3(2). https://doi.org/10.5847/wjem.j.issn.1920-8642.2012.02.006.
- Montoya, KF, Charry, JD, Calle-Toro, JS, Núñez, LR, Poveda, G. (2015). Shock index as a mortality predictor in patients with acute polytrauma. Journal of Acute Disease, 4(3). https://doi.org/10.1016/j.joad.2015.04.006.
- Morrison, CA, Carrick, MM, Norman, MA, Scott, BG, Welsh, FJ, Tsai, P, … et al (2011). Hypotensive resuscitation strategy reduces transfusion requirements and severe postoperative coagulopathy in trauma patients with hemorrhagic shock: Preliminary results of a randomized controlled trial. Journal of Trauma - Injury, Infection and Critical Care, 70(3). https://doi.org/10.1097/TA.0b013e31820e77ea.
- Murad, MK, Larsen, S, Husum, H. (2012). Prehospital trauma care reduces mortality. Ten-year results from a time-cohort and trauma audit study in Iraq. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 20. https://doi.org/10.1186/1757-7241-20-13.
- Mutschler, M, Nienaber, U, Münzberg, M, Wölfl, C, Schoechl, H, Paffrath, T, … et al (2013). The Shock Index revisited - a fast guide to transfusion requirement? A retrospective analysis on 21,853 patients derived from the TraumaRegister DGU®. Critical Care, 17(4). https://doi.org/10.1186/cc12851.
- Neeki, MM, Dong, F, Toy, J, Vaezazizi, R, Powell, J, Wong, D, … et al (2018). Tranexamic acid in civilian trauma care in the California Prehospital Antifibrinolytic Therapy study. Western Journal of Emergency Medicine, 19(6). https://doi.org/10.5811/westjem.2018.8.39336.
- Pandit, V, Rhee, P, Hashmi, A, Kulvatunyou, N, Tang, A, Khalil, M, … et al (2014). Shock index predicts mortality in geriatric trauma patients: An analysis of the National Trauma Data Bank. Journal of Trauma and Acute Care Surgery, 76(4). https://doi.org/10.1097/TA.0000000000000160.
- Paravar, M, Hosseinpour, M, Mohammadzadeh, M, Mirzadeh, AS. (2014). Prehospital care and in-hospital mortality of trauma patients in Iran. Prehospital and Disaster Medicine, 29(5). https://doi.org/10.1017/S1049023X14000879.
- Pfeifer, R, Halvachizadeh, S, Schick, S, Sprengel, K, Jensen, KO, Teuben, M, … et al (2019). Are Pre-hospital Trauma Deaths Preventable? A Systematic Literature Review. In World Journal of Surgery (Vol. 43, Issue 10). https://doi.org/10.1007/s00268-019-05056-1.
- Ramesh, GH, Uma, JC, Farhath, S. (2019). Fluid resuscitation in trauma: What are the best strategies and fluids? In International Journal of Emergency Medicine (Vol. 12, Issue 1). https://doi.org/10.1186/s12245-019-0253-8.
- Sampalis, JS, Tamim, H, Denis, R, Boukas, S, Ruest, SA, Nikolis, A, … et al (1997). Ineffectiveness of on-site intravenous lines: Is prehospital time the culprit? Journal of Trauma - Injury, Infection and Critical Care, 43(4). https://doi.org/10.1097/00005373-199710000-00008.
- Schroll, R, Swift, D, Tatum, D, Couch, S, Heaney, JB, Llado-Farrulla, M, … et al (2018). Accuracy of shock index versus ABC score to predict need for massive transfusion in trauma patients. Injury, 49(1). https://doi.org/10.1016/j.injury.2017.09.015.
- Shangguan, Q, Xu, JS, Su, H, Li, JX, Wang, WY, Hong, K, Cheng, XS. (2015). Modified shock index is a predictor for 7-day outcomes in patients with STEMI. American Journal of Emergency Medicine, 33(8). https://doi.org/10.1016/j.ajem.2015.04.066.
- Stiell, IG, Nesbitt, LP, Pickett, W, Munkley, D, Spaite, DW, Banek, J, … et al (2008). The OPALS Major Trauma Study: Impact of advanced life-support on survival and morbidity. CMAJ. Canadian Medical Association Journal, 178(9). https://doi.org/10.1503/cmaj.071154.
- Tran, A, Yates, J, Lau, A, Lampron, J, & Matar, M. (2018). Permissive hypotension versus conventional resuscitation strategies in adult trauma patients with hemorrhagic shock: A systematic review and meta-analysis of randomized controlled trials. In Journal of Trauma and Acute Care Surgery (Vol. 84, Issue 5). https://doi.org/10.1097/TA.0000000000001816.
- Yaghoubian, A, Lewis, RJ, Putnam, B, De Virgilio, C. (2007). Reanalysis of prehospital intravenous fluid administration in patients with penetrating truncal injury and field hypotension. American Surgeon, 73(10). https://doi.org/10.1177/000313480707301023.
Düzeltme:
EMS’DE HEMORAJİK TRAVMA OLGULARINDA ŞOK İNDEXİNİN SIVI TEDAVİSİNDE BELİRLEYİCİ ROLÜ: RETROSPEKTİF BİR ÇALIŞMA
Yıl 2023,
Cilt: 8 Sayı: 3, 294 - 307, 03.01.2024
Ali Ekşi
,
Sevgi Öztürk Günay
Süreyya Gümüşsoy
,
Yusuf Ali Altuncı
,
Funda Karbek Akarca
Öz
Amaç: Çalışmanın amacı, hastane öncesi acil bakımda aktif kanaması olan travma hastalarına sıvı tedavisi başlamada, şok indeksinin (SI) belirleyici rolünün değerlendirilmesidir.
Yöntem: Bir üniversite hastanesi acil servisine 01.07.2010-01.07.2020 tarihleri arasında, acil yardım ambulansları ile getirilen 18 yaş ve üzeri, aktif kanaması olan travma hastaları taranmıştır. Toplam 3367 hasta dosyası taranmış, araştırmaya alınma kriterlerine uyan 587 hasta çalışmaya dahil edilmiştir. Hastaların şok indeksleri (SI) EMS ambulansında ilk ölçülen vital bulguları esas alınarak hesaplanmıştır. Bağımsız ve bağımlı değişkenler arasındaki ilişkinin belirlenmesinde ki-kare testi kullanılmıştır. Sonuçlar %95 güven aralığında değerlendirilmiştir ve p<0,05 istatistiksel olarak anlamlı kabul edilmiştir.
Bulgular: Hastaların, %76.7’sine hastane öncesinde >500 mL IV kristaloid sıvı uygulandığı, %66.4’ünde hastane öncesi SI’a göre hemorajik şok olduğu, %60.3’ünün ilk ölçülen sistolik kan basıncının>90 mmHg olduğu bulunmuştur. Hastanede ex olanların hastane öncesi SI ortalamaları taburcu olanlarınkinden daha yüksektir. SI’a göre şok olmayan hastalardan hastane öncesi IV sıvı uygulananlarda, hastanede ex olma durumunun daha yüksek olduğu bulunmuştur.
Sonuç: SI hastane öncesi travmalı hastanın tanımlanmasında ve mortalite değerlendirmesinde bir araç olarak kullanılabilir. Hastane öncesi sıvı tedavisi ihtiyacının belirlenmesinde SI belirleyici bir araç olarak kullanılabilir.
Kaynakça
- Berger, T, Green, J, Horeczko, T, Hagar, Y, Garg, N, Suarez, A, Panacek, E, & Shapiro, N. (2013). Shock index and early recognition of sepsis in the Emergency Department: Pilot study. Western Journal of Emergency Medicine, 14(2). https://doi.org/10.5811/westjem.2012.8.11546.
- Birkhahn, RH, Gaeta, TJ, Terry, D, Bove, JJ, & Tloczkowski, J. (2005). Shock index in diagnosing early acute hypovolemia. American Journal of Emergency Medicine, 23(3). https://doi.org/10.1016/j.ajem.2005.02.029.
Björkman, J, Raatiniemi, L, Setälä, P., Nurmi, J. (2021). Shock index as a predictor for short-term mortality in helicopter emergency medical services: A registry study. Acta Anaesthesiologica Scandinavica, 65(6). https://doi.org/10.1111/aas.13765.
- Bores, SA, Pajerowski, W, Carr, BG, Holena, D, Meisel, ZF, Mechem, CC, Band, RA. (2018). The Association of Prehospital Intravenous Fluids and Mortality in Patients with Penetrating Trauma. Journal of Emergency Medicine, 54(4). https://doi.org/10.1016/j.jemermed.2017.12.046.
- Bourque, JS-C, Cliche, J, Chauny, J, Daoust, R, Paquet, J, Piette, É. (2013). Accuracy of the shock index and various modified shock indexes to predict early mortality in patients suffering from gastrointestinal haemorrhage. Critical Care, 17(S2). https://doi.org/10.1186/cc12157.
- Cannon, CM, Braxton, CC, Kling-Smith, M, Mahnken, JD, Carlton, E, Moncure, M. (2009). Utility of the shock index in predicting mortality in traumatically injured patients. Journal of Trauma - Injury, Infection and Critical Care, 67(6). https://doi.org/10.1097/TA.0b013e3181bbf728.
- Cannon, JW, Khan, MA, Raja, AS, Cohen, MJ, Como, JJ, Cotton, BA, Dubose, JJ, Fox, EE, Inaba, K, Rodriguez, CJ, Holcomb, JB, Duchesne, JC. (2017). Damage control resuscitation in patients with severe traumatic hemorrhage: A practice management guideline from the Eastern Association for the Surgery of Trauma. Journal of Trauma and Acute Care Surgery, 82(3). https://doi.org/10.1097/TA.0000000000001333.
- Chen, CH, Shin, S Do, Sun, JT, Jamaluddin, SF, Tanaka, H, Song, KJ, Kajino, K, Kimura, A, Huang, EPC, Hsieh, MJ, Ma, MHM., Chiang, WC. (2020). Association between prehospital time and outcome of trauma patients in 4 Asian countries: A cross-national, multicenter cohort study. PLoS Medicine, 17(10). https://doi.org/10.1371/journal.pmed.1003360.
- Duchesne, JC, Kimonis, K, Marr, AB, Rennie, KV, Wahl, G, Wells, JE, Islam, TM, Meade, P, Stuke, L, Barbeau, JM, Hunt, JP, Baker, CC, McSwain, NE. (2010). Damage control resuscitation in combination with damage control laparotomy: A survival advantage. Journal of Trauma - Injury, Infection and Critical Care, 69(1). https://doi.org/10.1097/TA.0b013e3181df91fa.
- Dula, DJ, Wood, GC, Rejmer, AR, Starr, M, Leicht, M. (2002). U SE OF P REHOSPITAL F LUIDS IN H YPOTENSIVE B LUNT T RAUMA P ATIENTS. Prehospital Emergency Care, 6(4), 417–420.
- Dutton, RP, Mackenzie, CF, Scalea, TM. (2002). Hypotensive resuscitation during active hemorrhage; impact on in-hospital mortality. Journal of Trauma, 52(6). https://doi.org/10.1097/00005373-200206000-00020.
- Erol, G, Aytaç, İ, Güven Aytaç, B. (2021). Do shock index, modified shock index, and shock index by age have a predictive value in determining the risk of post-spinal hypotension in elderly patients? Turk Geriatri Dergisi, 24(3). https://doi.org/10.31086/tjgeri.2021.233.
- Geeraedts, LMG, Pothof, LAH, Caldwell, E, De Lange-De Klerk, ESM., D’Amours, SK. (2015). Prehospital fluid resuscitation in hypotensive trauma patients: Do we need a tailored approach? Injury, 46(1). https://doi.org/10.1016/j.injury.2014.08.001.
- Hampton, DA, Fabricant, LJ, Differding, J, Diggs, B, Underwood, S, De La Cruz, D, … et al (2013). Prehospital intravenous fluid is associated with increased survival in trauma patients. Journal of Trauma and Acute Care Surgery, 75(1 SUPPL1). https://doi.org/10.1097/TA.0b013e318290cd52.
- Haut, ER, Kalish, BT, Cotton, BA, Efron, DT, Haider, AH, Stevens, KA, … et al 011). Prehospital intravenous fluid administration is associated with higher mortality in trauma patients: A national trauma data bank analysis. Annals of Surgery, 253(2). https://doi.org/10.1097/SLA.0b013e318207c24f.
- Katayama, Y., Kitamura, T., Kiyohara, K., Ishida, K., Hirose, T., Nakao, S., … et al (2022). Effect of fluid administration on scene to traffic accident patients by EMS personnel: a propensity score-matched study using population-based ambulance records and nationwide trauma registry in Japan. European Journal of Trauma and Emergency Surgery, 48(2). https://doi.org/10.1007/s00068-020-01590-z.
- Kauvar, DS, Lefering, R, Wade, CE. (2006). Impact of hemorrhage on trauma outcome: An overview of epidemiology, clinical presentations, and therapeutic considerations. Journal of Trauma - Injury, Infection and Critical Care, 60(6 SUPPL.). https://doi.org/10.1097/01.ta.0000199961.02677.19.
- Kim, DK, Jeong, J, Shin, S Do, Song, KJ, Hong, KJ, Ro, YS, Kim, TH, … et al(2021). Association between prehospital field to emergency department delta shock index and in-hospital mortality in patients with torso and extremity trauma: A multinational, observational study. PLoS ONE, 16(10 October). https://doi.org/10.1371/journal.pone.0258811.
- Kudo, D, Yoshida, Y, Kushimoto, S. (2017). Permissive hypotension/hypotensive resuscitation and restricted/controlled resuscitation in patients with severe trauma. In Journal of Intensive Care (Vol. 5, Issue 1). https://doi.org/10.1186/s40560-016-0202-z.
- Liu, Y, Liu, J, Fang, ZA, Shan, G, Xu, J, Qi, Z, … et al (2012). Modified shock index and mortality rate of emergency patients. World Journal of Emergency Medicine, 3(2). https://doi.org/10.5847/wjem.j.issn.1920-8642.2012.02.006.
- Montoya, KF, Charry, JD, Calle-Toro, JS, Núñez, LR, Poveda, G. (2015). Shock index as a mortality predictor in patients with acute polytrauma. Journal of Acute Disease, 4(3). https://doi.org/10.1016/j.joad.2015.04.006.
- Morrison, CA, Carrick, MM, Norman, MA, Scott, BG, Welsh, FJ, Tsai, P, … et al (2011). Hypotensive resuscitation strategy reduces transfusion requirements and severe postoperative coagulopathy in trauma patients with hemorrhagic shock: Preliminary results of a randomized controlled trial. Journal of Trauma - Injury, Infection and Critical Care, 70(3). https://doi.org/10.1097/TA.0b013e31820e77ea.
- Murad, MK, Larsen, S, Husum, H. (2012). Prehospital trauma care reduces mortality. Ten-year results from a time-cohort and trauma audit study in Iraq. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 20. https://doi.org/10.1186/1757-7241-20-13.
- Mutschler, M, Nienaber, U, Münzberg, M, Wölfl, C, Schoechl, H, Paffrath, T, … et al (2013). The Shock Index revisited - a fast guide to transfusion requirement? A retrospective analysis on 21,853 patients derived from the TraumaRegister DGU®. Critical Care, 17(4). https://doi.org/10.1186/cc12851.
- Neeki, MM, Dong, F, Toy, J, Vaezazizi, R, Powell, J, Wong, D, … et al (2018). Tranexamic acid in civilian trauma care in the California Prehospital Antifibrinolytic Therapy study. Western Journal of Emergency Medicine, 19(6). https://doi.org/10.5811/westjem.2018.8.39336.
- Pandit, V, Rhee, P, Hashmi, A, Kulvatunyou, N, Tang, A, Khalil, M, … et al (2014). Shock index predicts mortality in geriatric trauma patients: An analysis of the National Trauma Data Bank. Journal of Trauma and Acute Care Surgery, 76(4). https://doi.org/10.1097/TA.0000000000000160.
- Paravar, M, Hosseinpour, M, Mohammadzadeh, M, Mirzadeh, AS. (2014). Prehospital care and in-hospital mortality of trauma patients in Iran. Prehospital and Disaster Medicine, 29(5). https://doi.org/10.1017/S1049023X14000879.
- Pfeifer, R, Halvachizadeh, S, Schick, S, Sprengel, K, Jensen, KO, Teuben, M, … et al (2019). Are Pre-hospital Trauma Deaths Preventable? A Systematic Literature Review. In World Journal of Surgery (Vol. 43, Issue 10). https://doi.org/10.1007/s00268-019-05056-1.
- Ramesh, GH, Uma, JC, Farhath, S. (2019). Fluid resuscitation in trauma: What are the best strategies and fluids? In International Journal of Emergency Medicine (Vol. 12, Issue 1). https://doi.org/10.1186/s12245-019-0253-8.
- Sampalis, JS, Tamim, H, Denis, R, Boukas, S, Ruest, SA, Nikolis, A, … et al (1997). Ineffectiveness of on-site intravenous lines: Is prehospital time the culprit? Journal of Trauma - Injury, Infection and Critical Care, 43(4). https://doi.org/10.1097/00005373-199710000-00008.
- Schroll, R, Swift, D, Tatum, D, Couch, S, Heaney, JB, Llado-Farrulla, M, … et al (2018). Accuracy of shock index versus ABC score to predict need for massive transfusion in trauma patients. Injury, 49(1). https://doi.org/10.1016/j.injury.2017.09.015.
- Shangguan, Q, Xu, JS, Su, H, Li, JX, Wang, WY, Hong, K, Cheng, XS. (2015). Modified shock index is a predictor for 7-day outcomes in patients with STEMI. American Journal of Emergency Medicine, 33(8). https://doi.org/10.1016/j.ajem.2015.04.066.
- Stiell, IG, Nesbitt, LP, Pickett, W, Munkley, D, Spaite, DW, Banek, J, … et al (2008). The OPALS Major Trauma Study: Impact of advanced life-support on survival and morbidity. CMAJ. Canadian Medical Association Journal, 178(9). https://doi.org/10.1503/cmaj.071154.
- Tran, A, Yates, J, Lau, A, Lampron, J, & Matar, M. (2018). Permissive hypotension versus conventional resuscitation strategies in adult trauma patients with hemorrhagic shock: A systematic review and meta-analysis of randomized controlled trials. In Journal of Trauma and Acute Care Surgery (Vol. 84, Issue 5). https://doi.org/10.1097/TA.0000000000001816.
- Yaghoubian, A, Lewis, RJ, Putnam, B, De Virgilio, C. (2007). Reanalysis of prehospital intravenous fluid administration in patients with penetrating truncal injury and field hypotension. American Surgeon, 73(10). https://doi.org/10.1177/000313480707301023.