Terpenes in Mushrooms: Natural Products with Diverse Therapeutic Activities

Eda Avcı; Ayşe Kuruüzüm-uz; Didem Şöhretoğlu

doi:10.52794/hujpharm.1790368

Terpenes in Mushrooms: Natural Products with Diverse Therapeutic Activities

Abstract

This study provides a comprehensive review of the terpenes found in mushrooms and their potential therapeutic applications. Mushrooms are rich sources of various terpenes, including monoterpenes, sesquiterpenes, diterpenes, and triterpenes, which possess antibacterial, antiviral, antifungal, antiparasitic, antioxidant, anti-inflammatory, antidiabetic, and cytotoxic activities. Notable examples include pleuromutilin, a precursor of the antibiotic retapamulin; ganoderic acids from Ganoderma lucidum with anti-HIV effects; sesquiterpenes from Albatrellus dispansus that are effective against phytopathogenic fungi; and lanostane triterpenes from G. lucidum and G. leucocontextum with neuroprotective effects. The present findings highlight the therapeutic potential of mushroom terpenes. However, the authors underscore the necessity for further in vitro studies to elucidate the mechanisms of action, along with in vivo studies, toxicity investigations, and clinical trials.

Keywords

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Details

Primary Language

English

Subjects

Pharmacognosy

Journal Section

Review

Authors

Eda Avcı
0009-0009-4807-810X
Türkiye

Ayşe Kuruüzüm-uz
0000-0003-3373-4759
Türkiye

Didem Şöhretoğlu ^*
0000-0002-8264-5544
Türkiye

Publication Date

March 1, 2026

Submission Date

September 24, 2025

Acceptance Date

November 10, 2025

Published in Issue

Year 2026 Volume: 46 Number: 1

DOI

https://doi.org/10.52794/hujpharm.1790368

IZ

https://izlik.org/JA83LW68FL

Cite

RIS / Bibtex

APA

Avcı, E., Kuruüzüm-uz, A., & Şöhretoğlu, D. (2026). Terpenes in Mushrooms: Natural Products with Diverse Therapeutic Activities. Hacettepe University Journal of the Faculty of Pharmacy, 46(1), 61-71. https://doi.org/10.52794/hujpharm.1790368

AMA

1.Avcı E, Kuruüzüm-uz A, Şöhretoğlu D. Terpenes in Mushrooms: Natural Products with Diverse Therapeutic Activities. HUJPHARM. 2026;46(1):61-71. doi:10.52794/hujpharm.1790368

Chicago

Avcı, Eda, Ayşe Kuruüzüm-uz, and Didem Şöhretoğlu. 2026. “Terpenes in Mushrooms: Natural Products With Diverse Therapeutic Activities”. Hacettepe University Journal of the Faculty of Pharmacy 46 (1): 61-71. https://doi.org/10.52794/hujpharm.1790368.

EndNote

Avcı E, Kuruüzüm-uz A, Şöhretoğlu D (March 1, 2026) Terpenes in Mushrooms: Natural Products with Diverse Therapeutic Activities. Hacettepe University Journal of the Faculty of Pharmacy 46 1 61–71.

IEEE

[1]E. Avcı, A. Kuruüzüm-uz, and D. Şöhretoğlu, “Terpenes in Mushrooms: Natural Products with Diverse Therapeutic Activities”, HUJPHARM, vol. 46, no. 1, pp. 61–71, Mar. 2026, doi: 10.52794/hujpharm.1790368.

ISNAD

Avcı, Eda - Kuruüzüm-uz, Ayşe - Şöhretoğlu, Didem. “Terpenes in Mushrooms: Natural Products With Diverse Therapeutic Activities”. Hacettepe University Journal of the Faculty of Pharmacy 46/1 (March 1, 2026): 61-71. https://doi.org/10.52794/hujpharm.1790368.

JAMA

1.Avcı E, Kuruüzüm-uz A, Şöhretoğlu D. Terpenes in Mushrooms: Natural Products with Diverse Therapeutic Activities. HUJPHARM. 2026;46:61–71.

MLA

Avcı, Eda, et al. “Terpenes in Mushrooms: Natural Products With Diverse Therapeutic Activities”. Hacettepe University Journal of the Faculty of Pharmacy, vol. 46, no. 1, Mar. 2026, pp. 61-71, doi:10.52794/hujpharm.1790368.

Vancouver

1.Eda Avcı, Ayşe Kuruüzüm-uz, Didem Şöhretoğlu. Terpenes in Mushrooms: Natural Products with Diverse Therapeutic Activities. HUJPHARM. 2026 Mar. 1;46(1):61-7. doi:10.52794/hujpharm.1790368