Harran Üniversitesi Tıp Fakültesi Dergisi

1304-9623 1309-4025

Harran University

10.35440/hutfd.661424

Clinical Sciences

Klinik Tıp Bilimleri

Evaluation of Complete Blood Count Parameters in Tubal Ectopic Pregnancy

Tubal Ektopik Gebelik Tanısında Tam Kan Sayımı Parametrelerinin Değerlendirilmesi

https://orcid.org/0000-0002-2443-1927

Turan

Gökçe

Gazi University, School of Medicine, Department of Obstetrics and Gynecology, Ankara, Turkey

https://orcid.org/0000-0001-6856-1822

Aslan Çetin

Berna

Kanuni Sultan Suleyman Training and Research Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey

https://orcid.org/0000-0002-0406-4883

Demirezen

Gözde

Tekirdağ State Hospital, Department of Obstetrics and Gynecology, Tekrdağ, Turkey

https://orcid.org/0000-0002-3285-9990

Peker

Nurullah

Dicle University, Faculty of Medicine, Department of Obstetrics and Gynecology, Diyarbakır, Turkey

04 29 2020

17 1 65 69 12 19 2019 03 09 2020

2004

Journal of Harran University Medical Faculty

Background: The aim of this study was to compare the hemogram parameters of patients with ectopic pregnancy (EP) and healthy intrauterine pregnancy.Materials and Methods: Between January 2013 and January 2017, the demographic data of patients with first-trimester intrauterine pregnancy and patients with a diagnosis of tubal EP issue in a tertiary center, and white blood cell count (WBC), hemoglobin (Hgb), hematocrit (Hct), neutrophil and lymphocyte count, neutrophil-lymphocyte ratio (NLR), platelet count (PLT), platelet lymphocyte ratio (PLR) and mean platelet volume (MPV) values on complete blood count were recorded and compared with each other.Results: A total of 718 patients with ectopic pregnancies and 937 patients with healthy intrauterine pregnancies were included in the present study. Between groups, age, gravida, parity, and abortion in the group with EP (study group) were monitored significantly higher (p <0.001), the gestational week was found significantly higher in the control group (p <0.001). Hgb, Hct and MPV values of the groups were monitored significantly higher in the Control Group (p<0.001), and no significant differences were detected between the WBC, PLT, NLR and PLR values of both groups.Conclusions: As a result, only the MPV value was found significant among the hemogram parameters in predicting ectopic pregnancy. In this study, NLR and PLR values were not found significant in the diagnosis of EP. Prospective studies with larger participants are needed to investigate more possible relationships with hemogram, NLR and PLR values in EP diagnosis and treatment protocols.

Amaç: Bu çalışmadaki amaç ektopik gebeliği (EG) olan hastalar ile sağlıklı intrauterin gebeliği olan hastaların hemogram parametrelerini karşılaştırmaktır.Materyal ve Metod: Ocak 2013 ile Ocak 2017 tarihleri arasında tersiyer bir merkezde tubal EG tanısı konan hastalar ile ilk trimester intrauterin gebeliği olan hastaların demografik verileri ve tam kan sayımındaki beyaz küre (WBC), hemoglobin (Hgb), hematokrit (Hct), nötrofil, lenfosit, platelet (PLT), ortalama platelet hacmi (MPV), nötrofil-lenfosit oranı (NLO) ve platelet-lenfosit oranı (PLO) karşılaştırıldı.Bulgular: EG’i olan 718 hasta ile sağlıklı intrauterin gebeliği olan 937 hasta çalışmaya dahil edildi. Yaş, gravida, parite ve abortus EG grubunda (çalışma grubu) anlamlı olarak daha yüksek izlenirken (p<0,001), gestasyonel hafta ise kontrol grubunda anlamlı olarak yüksek bulundu (p<0,001). Hgb, Hct ve MPV değerleri kontrol grubunda anlamlı olarak yüksek izlenirken (p<0,001), WBC, PLT, NLO ve PLO değerleri karşılaştırıldığında iki grup arasında anlamlı fark izlenmedi.Sonuç: Sonuç olarak EG’i öngörmede hemogram parametrelerinden sadece MPV değeri anlamlı bulundu. Bu çalışmada NLO ve PLO değerleri EG tanısında anlamlı bulunmadı. EG tanı ve tedavi protokollerinde hemogram, NLO ve PLO değerleri daha olası ilişkileri araştırmak için daha geniş hasta gruplarının inceleneceği prospektif çalışmalara ihtiyaç vardır.

Ektopik gebelik Mean platelet volume Nötrofil-lenfosit oranı Platelet-lenfosit oranı

Ectopic pregnancy Mean platelet volume Neutrophil-lymphocyte ratio Platelet-lymphocyte ratio

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