Year 2020, Volume , Issue 10, Pages 107 - 122 2020-04-17

İnsan Hastalıklarında Epigenetiğin Rolüne Klinik Bakış
Clinical Overview of the Role of Epigenetics in Human Diseases

Emre ÖZGÜR [1] , Hülya TIĞLI [2] , Hatice TIĞLI [3]


Son yıllarda sayısı giderek artan çalışmalar, epigenetik değişikliklerin hastalık süreci üzerinde önemli etkilerinin olduğunu ortaya koymaktadır. Bu süreçte teknolojik gelişmelerin de büyük katkıları ile epigenetik bilgi genetiğin ötesine taşınmıştır. Epigenetik konusunda elde edilen yeni bulgular sadece hastalıklarla ilişkili faktörleri daha iyi anlamamızı sağlamakla kalmaz, aynı zamanda terapötik girişim için yeni kapılar da açmaktadır. Bu derlemede, epigenetik kavramı ve insan hastalıklarında epigenetiğin önemi irdelenmiştir.

In recent years, a growing number of studies have shown that epigenetic changes have significant effects on the disease process. In this process, epigenetic knowledge has gone beyond genetics with the great contributions of technological developments. New findings in epigenetics not only enable us to better understand the disease-related factors but also open new doors for therapeutic intervention. In this review, the concept of epigenetics and the importance of epigenetics in human diseases are examined.

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Primary Language tr
Subjects Medicine
Journal Section Articles
Authors

Orcid: 0000-0002-4995-4759
Author: Emre ÖZGÜR
Institution: İSTANBUL ÜNİVERSİTESİ, ONKOLOJİ ENSTİTÜSÜ
Country: Turkey


Orcid: 0000-0001-5997-0122
Author: Hülya TIĞLI (Primary Author)
Institution: İSTANBUL GELİŞİM ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ YÜKSEKOKULU
Country: Turkey


Orcid: 0000-0001-9713-4926
Author: Hatice TIĞLI
Institution: İSTANBUL GELİŞİM ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ YÜKSEKOKULU
Country: Turkey


Dates

Publication Date : April 17, 2020

Bibtex @review { igusabder653270, journal = {İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi}, issn = {2536-4499}, eissn = {2602-2605}, address = {İstanbul Gelişim Üniversitesi Sağlık Bilimleri Yüksekokulu - Cihangir Mah. Şehit Jandarma Komando Er Hakan Öner Sk. No: 1 Avcılar / İstanbul / Türkiye}, publisher = {İstanbul Gelisim University}, year = {2020}, volume = {}, pages = {107 - 122}, doi = {10.38079/igusabder.653270}, title = {İnsan Hastalıklarında Epigenetiğin Rolüne Klinik Bakış}, key = {cite}, author = {Özgür, Emre and Tığlı, Hülya and Tığlı, Hatice} }
APA Özgür, E , Tığlı, H , Tığlı, H . (2020). İnsan Hastalıklarında Epigenetiğin Rolüne Klinik Bakış . İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi , (10) , 107-122 . DOI: 10.38079/igusabder.653270
MLA Özgür, E , Tığlı, H , Tığlı, H . "İnsan Hastalıklarında Epigenetiğin Rolüne Klinik Bakış" . İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi (2020 ): 107-122 <https://dergipark.org.tr/en/pub/igusabder/issue/53551/653270>
Chicago Özgür, E , Tığlı, H , Tığlı, H . "İnsan Hastalıklarında Epigenetiğin Rolüne Klinik Bakış". İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi (2020 ): 107-122
RIS TY - JOUR T1 - İnsan Hastalıklarında Epigenetiğin Rolüne Klinik Bakış AU - Emre Özgür , Hülya Tığlı , Hatice Tığlı Y1 - 2020 PY - 2020 N1 - doi: 10.38079/igusabder.653270 DO - 10.38079/igusabder.653270 T2 - İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi JF - Journal JO - JOR SP - 107 EP - 122 VL - IS - 10 SN - 2536-4499-2602-2605 M3 - doi: 10.38079/igusabder.653270 UR - https://doi.org/10.38079/igusabder.653270 Y2 - 2020 ER -
EndNote %0 İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi İnsan Hastalıklarında Epigenetiğin Rolüne Klinik Bakış %A Emre Özgür , Hülya Tığlı , Hatice Tığlı %T İnsan Hastalıklarında Epigenetiğin Rolüne Klinik Bakış %D 2020 %J İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi %P 2536-4499-2602-2605 %V %N 10 %R doi: 10.38079/igusabder.653270 %U 10.38079/igusabder.653270
ISNAD Özgür, Emre , Tığlı, Hülya , Tığlı, Hatice . "İnsan Hastalıklarında Epigenetiğin Rolüne Klinik Bakış". İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi / 10 (April 2020): 107-122 . https://doi.org/10.38079/igusabder.653270
AMA Özgür E , Tığlı H , Tığlı H . İnsan Hastalıklarında Epigenetiğin Rolüne Klinik Bakış. IGUSABDER. 2020; (10): 107-122.
Vancouver Özgür E , Tığlı H , Tığlı H . İnsan Hastalıklarında Epigenetiğin Rolüne Klinik Bakış. İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi. 2020; (10): 107-122.
IEEE E. Özgür , H. Tığlı and H. Tığlı , "İnsan Hastalıklarında Epigenetiğin Rolüne Klinik Bakış", İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi, no. 10, pp. 107-122, Apr. 2020, doi:10.38079/igusabder.653270