Year 2018,
Volume: 4 Issue: 1, 13 - 23, 01.04.2018
Harun R. Özdal
,
Bihter Yıldız
Güner Arkun
References
- Izquierdo-Pulido, M., & Vidal-Carou, M. C. (1997).
Determination of free and total furfural compounds
in infant milk formulas by high-performance liquid
chromatography. Journal of Agricultural and Food
Chemistry, 45(6), 2128-2133.
- [2] Ames, J.M., (1998). Applications of the
Maillard reaction in the food industry. Food
Chemistry 62(4): 431-439.
- [3] Antal, M. J., Mok, W.S.L., Richards,
G.N., (1990). Mechanism of formation of
5-hydroxymethy)-2furaldehyde from D-fructose
and sucrose. Carbohydr. Res. 199, 91–109.
- [4] Anonim, (2000). Türk Gıda Kodeksi Çiğ Süt ve
Isıl İşlem Görmüş İçme Sütleri Tebliği. T.C. Resmi
Gazete, Sayı: 23964. Tarım ve Köyişleri Bakanlığı,
Ankara.
- [5] Anonim, (2016). Çiğ Süt Neden Isıl İşlemden
Geçmeli, Süt Hakkında Aklımızda bir şey
kalmasın,http://www.hurriyet.com.tr/paylas/suthakkinda-
aklinizda-bir-soru-kalmasin-2361.
- [6] Anet, E.F.L.J., (1964). 3-Deoxyglycosuloses
(3-deoxyglucosones) and the degradation of
carbonhydrates, Advances Carbonhydrate
Research 19; 181-218.
- [7] Anon., 2018 (https://www.foodelphi.com/tag/
sutun-tanimi/, Accessed May 2, 2018).
- [8] Arena, S., Renzone, G., D’Ambrosio, C.,
Salzano, A.M., Scaloni, A., (2017). Dairy products
and the Maillard reaction: A promising future
for extensive food characterization by integrated
proteomics studies. Food Chemistry 219: 477–489.
- [9] Baldwin, A.J., Ackland, J.D., (1991). Effect
of preheat treatment and storage on the properties
of whole milk powder. Changes in physical and
chemical properties. Netherland Milk Dairy
Journal, 45, 169-181.
- [10] Berg, H.E., Van Boekel, M.A.J.S., (1994).
Degradation of lactose during heating of milk. 1.
reaction pathways. Netherlands Milk and Dairy
Journal 48: 157-175.
- [11] Burdurlu, H. S. and Karadeniz, F. (2003).
Effect of storage on nonenzymatic browning of
apple juice concentrates. Food Chemistry, 80, 91-
97.
- [12] Bolin, H. R. and Steele, R. J. (1987).
Nonenzymatic browning in dried apples during
storage. Journal of Food Science, 52(6), 1654-
1657.
- [13] Chavez-Servin, JL, Castellote, AI, Lopez-
Sabater, (2005). C. Analysis of potential and free
furfural compounds in milk-based formula by highperformance
liquid chromatography evolution
during storage. Journal of Chromatography A.,
1076: 133-140.
- [14] Coca, M., Garcia, M.T., Gonzalez, G., Pena,
M., and Garcia, J.A., (2004). Study of colored
compounds formed in sugar beet processing, Food
Chemistry 86(3); 421-433.
- [15] Çelebi, I., (2006). Color formation in wheat
starch based glucose syrups and use of activated
carbons for sugar decolorization, a thesis of
Master, Natural and Applied Sciences of Middle
East Technical University, p: 27-33.
- [16] Daniel, J. R. and Whistler, R. L., (1985).
Carbonhydrates. In ‘Food Chemistry’, O. R.
Fennama (Ed.), second edition, Marcel Dekker, p.
70-137, New York.
- [17] Dmytrów, I., Mituniewicz-Małek, A., &
Balejko, J., (2010). Assessment of selected
physicochemical parameters of UHT sterilized
goat’s milk. Electr. J. Pol. Agric. Univ. Food Sci.
Technol, 13(2), 09.
- [18] Edward, W.P., (2000). The Maillard Reactions.
In: The Science of Sugar Confectionery, Edited
by W.P. Edwards, Royal Society of Chemistry
Publication, Cambridge, pp. 9-13.
- [19] Evangelisti, F., Calcagno, C., Nardi, S.,
Zunin, P., (1999). Deterioration of protein fraction
by Maillard reaction in dietetic milks. Journal of
Dairy Research 66: 237-243.
- [20] Ferrer, E., Alegría, A., Courtois, G., Farré, R.,
(2000). High-performance liquid chromatographic
determination of Maillard compounds in storebrand
and name-brand ultra-high-temperature
treated cows’ milk. Journal of Chromatography A
881(1-2): 599–606.
- [21] Fox PF, McWeeney PLH., (2003). Advanced
Dairy Chemistry. Volume 1. In Chapter 1: Milk
Proteins: General and Historical Aspects. Third
Edition, Part A New York, Springer Verlag Publish.
- [22] Friedman, M.; Molnar-Perl, (1990), I.
Inhibition of browning by sulfur amino acids. I.
Heated amino acid-glucose systems. J. Agric. Food
Chem. 38, 1642-1647.
- [23] Haleva-Toledo, E., Naim, M., Zehavi, U.,
Rouseff, R.L., (1999). Effects of L-Cysteine and
N-Acetyl-Lcysteine on 4-Hydroxy-2,5-dimethyl-
3(2H)-furanone (Furaneol), 5-(Hydroxymethyl)
furfural, and 5methylfurfural Formation and
Browning in Buffer Solutions Containing either
Rhamnose or Glucose and Arginine J. Agric. Food
Chem. 47, 4140-4145.
- [24] Jansson, T., Clausen, M.R., Sundekilde,
U.K., Eggers, N., Nyegaard, S., Larsen, L.B.,
Ray, C., Sundgren, A., Andersen, H.J., Bertram,
H.C., (2014). Lactose-hydrolyzed milk is more
prone to chemical changes during storage than
conventional ultrahigh-temperature (UHT) milk.
Journal of Agricultural and Food Chemistry
62(31): 7886−7896.
- [25] Kroh, L.W., (1994). Caramelisation in food
and beverages. Food Chem., 51, 373-379.
- [26] Ledesma-Osuna, A.I., Ramos-Clamont, G.,
Vázquez-Moreno, L., (2008). Characterization
of bovine serum albumin glycated with glucose,
galactose and lactose. Acta Biochimica Polonica
55(3): 491-497.
- [27] Leiva, G.E., Naranjo, G.B., Malec, L.S.,
(2017). A study of different indicators of Maillard
reaction with whey proteins and different
carbohydrates under adverse storage conditions.
Food Chemistry 215: 410-416.
- [28] Maijala K., (2000). Cow milk and human
development and wellbeing. Livestock Production
Science. 65: 1-18.
- [29] Martins, S. I., Jongen, W. M., & Van Boekel,
M. A. (2000)., A review of Maillard reaction in
food and implications to kinetic modelling. Trends
in Food Science & Technology, 11(9-10), 364-373.
- [30] Martins, S.I.F.S., Jongen, W.M.F., Van Boekel,
M.A.J.S., (2001). A review of Maillard reaction in
food and implications to kinetic modelling. Trends
in Food Science & Technology 11: 364–373.
- [31] Marquez, F. M., Gomez, M., Hernandez, E.G.,
Villanova, B.G., (1992). New spectrophotometric
methods for measuring hydroxymethylfurfural in
powdered milk. Journal of Dairy Research, 59,
225-228.
- [32] Metin M., (1996). 5. Sütün Karbonhidratları,
13. Süte Uygulanan Isıl İşlemler Süt teknolojisi
129-130, 526-527.
- [33] Miller GD, Jarvis KJ, McBean LD. (2000).
Handbook of Dairy Foods and Nutrition. (Ed:
Jensen, Kroger). The Importance of Milk and Milk
Products in the Diet. New York. CRC Press. 4-24.
- [34] Morales, F. J., Romero, C., & Jimenez-Pérez,
S. (1992). An enhanced liquid chromatographic
method for 5-hydroxymethylfurfural determination
in UHT milk. Chromatographia, 33(1-2), 45-48.
- [35] Morales, J. F., Romero, C., Perez-Jimenez.,
S., (1996). Evaluation of heat-induced changes in
Spanish commercial milk: hydroxymethylfurfural
and available lysine content, Internatıonal Journal
of food science & technology, v.31 no.5, pp 411-
418
- [36] Morales, F.J., Jiménez-Pérez, S., (1999).
HMF formation during heat-treatment of milk-type
products as related to milkfat content. Journal of
Food Science 64(5): 855-859.
- [37] Naim, M., Wainish, S., Zehavi, U., Peleg,
H., Rouseff, R. L., Nagy, S., (1993). Inhibition by
thiol compounds of off-flavor formation in stored
orange juice. I. Effect of L-cysteine and N-acetyl-
L-cysteine on 2,5-dimethyl-4-hydroxy-3(2H)-
furanone formation. J. Agric. Food Chem., 41,
1355-1358.
- [38] Oral R.A, Dogan M, Sarioglu K, Toker OS.,
(2012). 5-hydroxymethyl furfural formation and
reaction kinetics of different pekmez samples:
effect of temperature and storage, International
Journal of Food Engineering. 2012; 8: 1556-3758.
- [39] Oral R.A, Dogan M, Sarıoglu K., (2014).
Effects of certain polyphenols and extracts on
furans and acrylamide formation in model system,
and total furans during storage. Food Chemistry.
2014; 142: 423-429.
- [40] Oral R.A, Mortaş M, Dogan M, Sarioglu
K, Yazici F., (2014). New Approaches to
Determination of HMF. Food Chemistry. 2014;
143: 367-370.
- [41] Oral, R.A., Dogan, M., Sarıoglu, K., Kayacıer,
A., & Sagdic, O. (2015). Determination of HMF
in Some Instant Foods and Its Biodegradation
by Some Lactic Acid Bacteria in Medium and
Food. Ann Chromatographia, Sep Tech, 1(1), 1004.
- [42] Pellegrino, L., Resmini, P., Luf, W., (1995).
Assessment (indices) of heat treatment of milk. In:
Heat-induced changes in milk, Edited by P.F. Fox,
Brussels, International Dairy Federation, 9501:
409–453 p.
- [43] Richardson, P., (2001). Thermal technologies
in food processing. Woodhead Publishing, 294,
England.
- [44] Sarımehmetoğlu B., Güvenli Süt Tüketimi
[online], Besin Hijyeni ve Teknolojisi, Ankara
Üniversitesi, https://www.foodelphi.com/tag/
sutun-tanimi/.
- [45] Sunds, A. V., Rauh, V. M., Sørensen, J., &
Larsen, L. B. (2018). Maillard reaction progress in
UHT milk during storage at different temperature
levels and cycles. International Dairy Journal, 77,
56-64.
- [46] Tossavainen, O., Kallioinen, H., (2007). Effect
of lactose hydrolysis on furosine formation in skim
milk during pasteurization. Milchwissenschaft
62(2): 188-191.
- [47] Urgu, M., Saatli, T. E., Türk, A., &
Koca, N. (2017). Isıl İşlem Görmüş İçme
Sütlerinde (Pastörize, UHT ve Laktozsuz
UHT Süt) Hidroksimetilfurfural İçeriğinin
Belirlenmesi. Akademik Gıda, 15(3), 249-255.
- [48] Ünal R. N., & Besler H. T., (2008). Beslenmede
sütün önemi. Sağlık Bakanlığı Yayın, (727).
- [49] Wedzicha, B.L., and McWeeny, D.J., (1974).
Non-enzymic browning reactions of ascorbic acid
and their inhibition, The production of 3-deoxy-
4-sulphopentosulose in mixtures of ascorbic acid
glycine and bisulphite ion, Journal of the Science
of Food and Agriculture 25; 577-587.
- [50] Van Boekel, M.A.J.S., (1998). Effect of heating
on Maillard reactions in milk. Food Chemistry
62(4): 403-414.
- [51] Yetişmeyen A., (1995). Süt teknolojisi. Ankara
Üniversitesi Ziraat Fakültesi Yayınları, (1420/420),
1997.
- [52] Yıldız, O., Şahin, H., Kara, M., Aliyazıcıoğlu,
R., Tarhan, Ö., & Kolaylı, S., (2010). Maillard
reaksiyonları ve reaksiyon ürünlerinin gıdalardaki
önemi. Akademik Gıda, 8(6), 44-51.
- [53] Zhijun Chen and Xiaomei Yan, (2009).
Simultaneous Determination of Melamine and
5-Hydroxymethylfurfural in Milk by Capillary
Electrophoresis with Diode Array Detection,
J.Agric Food Chem., 57(19), pp 8742-8747.
Hydroxymethylfurfural (Hmf) Formation in Milk and Dairy Products
Year 2018,
Volume: 4 Issue: 1, 13 - 23, 01.04.2018
Harun R. Özdal
,
Bihter Yıldız
Güner Arkun
Abstract
Milk and dairy products are encountered non-enzymatic browning reactions due to the heat process and
storage temperatures. These reactions occur in foodstuffs containing sugar and amino acids. As a result
of the reaction, undesirable compounds are formed in foods, so that the natural structure of the food is
deteriorated. It is of great importance to control and observe the 5-Hydroxymethyl-2-furaldehyde (HMF)
compound in milk and dairy products during the production process and storage period as a result of
the browning reaction due to the heat treatment. Formation of (HMF), which is heat treatment indicator
used as a chemical parameter to determine whether most food products with sugar concentration,
such as fruit juices, honey, molasses, jams, milk and dairy products, are stored under right conditions
and whether the appropriate heat treatment is carried out during the production process. In this study,
heat treatment was applied to milk and dairy products during production and hydroxymethylfurfural
(HMF) formation as a result of non-enzymatic chemical reactions have been investigated and evaluated.
References
- Izquierdo-Pulido, M., & Vidal-Carou, M. C. (1997).
Determination of free and total furfural compounds
in infant milk formulas by high-performance liquid
chromatography. Journal of Agricultural and Food
Chemistry, 45(6), 2128-2133.
- [2] Ames, J.M., (1998). Applications of the
Maillard reaction in the food industry. Food
Chemistry 62(4): 431-439.
- [3] Antal, M. J., Mok, W.S.L., Richards,
G.N., (1990). Mechanism of formation of
5-hydroxymethy)-2furaldehyde from D-fructose
and sucrose. Carbohydr. Res. 199, 91–109.
- [4] Anonim, (2000). Türk Gıda Kodeksi Çiğ Süt ve
Isıl İşlem Görmüş İçme Sütleri Tebliği. T.C. Resmi
Gazete, Sayı: 23964. Tarım ve Köyişleri Bakanlığı,
Ankara.
- [5] Anonim, (2016). Çiğ Süt Neden Isıl İşlemden
Geçmeli, Süt Hakkında Aklımızda bir şey
kalmasın,http://www.hurriyet.com.tr/paylas/suthakkinda-
aklinizda-bir-soru-kalmasin-2361.
- [6] Anet, E.F.L.J., (1964). 3-Deoxyglycosuloses
(3-deoxyglucosones) and the degradation of
carbonhydrates, Advances Carbonhydrate
Research 19; 181-218.
- [7] Anon., 2018 (https://www.foodelphi.com/tag/
sutun-tanimi/, Accessed May 2, 2018).
- [8] Arena, S., Renzone, G., D’Ambrosio, C.,
Salzano, A.M., Scaloni, A., (2017). Dairy products
and the Maillard reaction: A promising future
for extensive food characterization by integrated
proteomics studies. Food Chemistry 219: 477–489.
- [9] Baldwin, A.J., Ackland, J.D., (1991). Effect
of preheat treatment and storage on the properties
of whole milk powder. Changes in physical and
chemical properties. Netherland Milk Dairy
Journal, 45, 169-181.
- [10] Berg, H.E., Van Boekel, M.A.J.S., (1994).
Degradation of lactose during heating of milk. 1.
reaction pathways. Netherlands Milk and Dairy
Journal 48: 157-175.
- [11] Burdurlu, H. S. and Karadeniz, F. (2003).
Effect of storage on nonenzymatic browning of
apple juice concentrates. Food Chemistry, 80, 91-
97.
- [12] Bolin, H. R. and Steele, R. J. (1987).
Nonenzymatic browning in dried apples during
storage. Journal of Food Science, 52(6), 1654-
1657.
- [13] Chavez-Servin, JL, Castellote, AI, Lopez-
Sabater, (2005). C. Analysis of potential and free
furfural compounds in milk-based formula by highperformance
liquid chromatography evolution
during storage. Journal of Chromatography A.,
1076: 133-140.
- [14] Coca, M., Garcia, M.T., Gonzalez, G., Pena,
M., and Garcia, J.A., (2004). Study of colored
compounds formed in sugar beet processing, Food
Chemistry 86(3); 421-433.
- [15] Çelebi, I., (2006). Color formation in wheat
starch based glucose syrups and use of activated
carbons for sugar decolorization, a thesis of
Master, Natural and Applied Sciences of Middle
East Technical University, p: 27-33.
- [16] Daniel, J. R. and Whistler, R. L., (1985).
Carbonhydrates. In ‘Food Chemistry’, O. R.
Fennama (Ed.), second edition, Marcel Dekker, p.
70-137, New York.
- [17] Dmytrów, I., Mituniewicz-Małek, A., &
Balejko, J., (2010). Assessment of selected
physicochemical parameters of UHT sterilized
goat’s milk. Electr. J. Pol. Agric. Univ. Food Sci.
Technol, 13(2), 09.
- [18] Edward, W.P., (2000). The Maillard Reactions.
In: The Science of Sugar Confectionery, Edited
by W.P. Edwards, Royal Society of Chemistry
Publication, Cambridge, pp. 9-13.
- [19] Evangelisti, F., Calcagno, C., Nardi, S.,
Zunin, P., (1999). Deterioration of protein fraction
by Maillard reaction in dietetic milks. Journal of
Dairy Research 66: 237-243.
- [20] Ferrer, E., Alegría, A., Courtois, G., Farré, R.,
(2000). High-performance liquid chromatographic
determination of Maillard compounds in storebrand
and name-brand ultra-high-temperature
treated cows’ milk. Journal of Chromatography A
881(1-2): 599–606.
- [21] Fox PF, McWeeney PLH., (2003). Advanced
Dairy Chemistry. Volume 1. In Chapter 1: Milk
Proteins: General and Historical Aspects. Third
Edition, Part A New York, Springer Verlag Publish.
- [22] Friedman, M.; Molnar-Perl, (1990), I.
Inhibition of browning by sulfur amino acids. I.
Heated amino acid-glucose systems. J. Agric. Food
Chem. 38, 1642-1647.
- [23] Haleva-Toledo, E., Naim, M., Zehavi, U.,
Rouseff, R.L., (1999). Effects of L-Cysteine and
N-Acetyl-Lcysteine on 4-Hydroxy-2,5-dimethyl-
3(2H)-furanone (Furaneol), 5-(Hydroxymethyl)
furfural, and 5methylfurfural Formation and
Browning in Buffer Solutions Containing either
Rhamnose or Glucose and Arginine J. Agric. Food
Chem. 47, 4140-4145.
- [24] Jansson, T., Clausen, M.R., Sundekilde,
U.K., Eggers, N., Nyegaard, S., Larsen, L.B.,
Ray, C., Sundgren, A., Andersen, H.J., Bertram,
H.C., (2014). Lactose-hydrolyzed milk is more
prone to chemical changes during storage than
conventional ultrahigh-temperature (UHT) milk.
Journal of Agricultural and Food Chemistry
62(31): 7886−7896.
- [25] Kroh, L.W., (1994). Caramelisation in food
and beverages. Food Chem., 51, 373-379.
- [26] Ledesma-Osuna, A.I., Ramos-Clamont, G.,
Vázquez-Moreno, L., (2008). Characterization
of bovine serum albumin glycated with glucose,
galactose and lactose. Acta Biochimica Polonica
55(3): 491-497.
- [27] Leiva, G.E., Naranjo, G.B., Malec, L.S.,
(2017). A study of different indicators of Maillard
reaction with whey proteins and different
carbohydrates under adverse storage conditions.
Food Chemistry 215: 410-416.
- [28] Maijala K., (2000). Cow milk and human
development and wellbeing. Livestock Production
Science. 65: 1-18.
- [29] Martins, S. I., Jongen, W. M., & Van Boekel,
M. A. (2000)., A review of Maillard reaction in
food and implications to kinetic modelling. Trends
in Food Science & Technology, 11(9-10), 364-373.
- [30] Martins, S.I.F.S., Jongen, W.M.F., Van Boekel,
M.A.J.S., (2001). A review of Maillard reaction in
food and implications to kinetic modelling. Trends
in Food Science & Technology 11: 364–373.
- [31] Marquez, F. M., Gomez, M., Hernandez, E.G.,
Villanova, B.G., (1992). New spectrophotometric
methods for measuring hydroxymethylfurfural in
powdered milk. Journal of Dairy Research, 59,
225-228.
- [32] Metin M., (1996). 5. Sütün Karbonhidratları,
13. Süte Uygulanan Isıl İşlemler Süt teknolojisi
129-130, 526-527.
- [33] Miller GD, Jarvis KJ, McBean LD. (2000).
Handbook of Dairy Foods and Nutrition. (Ed:
Jensen, Kroger). The Importance of Milk and Milk
Products in the Diet. New York. CRC Press. 4-24.
- [34] Morales, F. J., Romero, C., & Jimenez-Pérez,
S. (1992). An enhanced liquid chromatographic
method for 5-hydroxymethylfurfural determination
in UHT milk. Chromatographia, 33(1-2), 45-48.
- [35] Morales, J. F., Romero, C., Perez-Jimenez.,
S., (1996). Evaluation of heat-induced changes in
Spanish commercial milk: hydroxymethylfurfural
and available lysine content, Internatıonal Journal
of food science & technology, v.31 no.5, pp 411-
418
- [36] Morales, F.J., Jiménez-Pérez, S., (1999).
HMF formation during heat-treatment of milk-type
products as related to milkfat content. Journal of
Food Science 64(5): 855-859.
- [37] Naim, M., Wainish, S., Zehavi, U., Peleg,
H., Rouseff, R. L., Nagy, S., (1993). Inhibition by
thiol compounds of off-flavor formation in stored
orange juice. I. Effect of L-cysteine and N-acetyl-
L-cysteine on 2,5-dimethyl-4-hydroxy-3(2H)-
furanone formation. J. Agric. Food Chem., 41,
1355-1358.
- [38] Oral R.A, Dogan M, Sarioglu K, Toker OS.,
(2012). 5-hydroxymethyl furfural formation and
reaction kinetics of different pekmez samples:
effect of temperature and storage, International
Journal of Food Engineering. 2012; 8: 1556-3758.
- [39] Oral R.A, Dogan M, Sarıoglu K., (2014).
Effects of certain polyphenols and extracts on
furans and acrylamide formation in model system,
and total furans during storage. Food Chemistry.
2014; 142: 423-429.
- [40] Oral R.A, Mortaş M, Dogan M, Sarioglu
K, Yazici F., (2014). New Approaches to
Determination of HMF. Food Chemistry. 2014;
143: 367-370.
- [41] Oral, R.A., Dogan, M., Sarıoglu, K., Kayacıer,
A., & Sagdic, O. (2015). Determination of HMF
in Some Instant Foods and Its Biodegradation
by Some Lactic Acid Bacteria in Medium and
Food. Ann Chromatographia, Sep Tech, 1(1), 1004.
- [42] Pellegrino, L., Resmini, P., Luf, W., (1995).
Assessment (indices) of heat treatment of milk. In:
Heat-induced changes in milk, Edited by P.F. Fox,
Brussels, International Dairy Federation, 9501:
409–453 p.
- [43] Richardson, P., (2001). Thermal technologies
in food processing. Woodhead Publishing, 294,
England.
- [44] Sarımehmetoğlu B., Güvenli Süt Tüketimi
[online], Besin Hijyeni ve Teknolojisi, Ankara
Üniversitesi, https://www.foodelphi.com/tag/
sutun-tanimi/.
- [45] Sunds, A. V., Rauh, V. M., Sørensen, J., &
Larsen, L. B. (2018). Maillard reaction progress in
UHT milk during storage at different temperature
levels and cycles. International Dairy Journal, 77,
56-64.
- [46] Tossavainen, O., Kallioinen, H., (2007). Effect
of lactose hydrolysis on furosine formation in skim
milk during pasteurization. Milchwissenschaft
62(2): 188-191.
- [47] Urgu, M., Saatli, T. E., Türk, A., &
Koca, N. (2017). Isıl İşlem Görmüş İçme
Sütlerinde (Pastörize, UHT ve Laktozsuz
UHT Süt) Hidroksimetilfurfural İçeriğinin
Belirlenmesi. Akademik Gıda, 15(3), 249-255.
- [48] Ünal R. N., & Besler H. T., (2008). Beslenmede
sütün önemi. Sağlık Bakanlığı Yayın, (727).
- [49] Wedzicha, B.L., and McWeeny, D.J., (1974).
Non-enzymic browning reactions of ascorbic acid
and their inhibition, The production of 3-deoxy-
4-sulphopentosulose in mixtures of ascorbic acid
glycine and bisulphite ion, Journal of the Science
of Food and Agriculture 25; 577-587.
- [50] Van Boekel, M.A.J.S., (1998). Effect of heating
on Maillard reactions in milk. Food Chemistry
62(4): 403-414.
- [51] Yetişmeyen A., (1995). Süt teknolojisi. Ankara
Üniversitesi Ziraat Fakültesi Yayınları, (1420/420),
1997.
- [52] Yıldız, O., Şahin, H., Kara, M., Aliyazıcıoğlu,
R., Tarhan, Ö., & Kolaylı, S., (2010). Maillard
reaksiyonları ve reaksiyon ürünlerinin gıdalardaki
önemi. Akademik Gıda, 8(6), 44-51.
- [53] Zhijun Chen and Xiaomei Yan, (2009).
Simultaneous Determination of Melamine and
5-Hydroxymethylfurfural in Milk by Capillary
Electrophoresis with Diode Array Detection,
J.Agric Food Chem., 57(19), pp 8742-8747.