The gradualincrease in health expenditure each year highlights the importance ofcost-controlled inpatient prospective payment systems in health financing inTurkey and around the world. Being in current use in many developed countries,the Diagnosis-related Groups (DRG) model is an effectiveinpatient prospective payment systemused in healthcare institutions with a highcase mix index. The present study aims to determine the efficacy of the DRGinpatient prospective payment system model in the funding of cardiovasculardiseases, and to reveal the differences between the CHP-basedand DRG-basedpricing models. Findings of the present study reveal that DRG pricing changeswhile CHP pricing remains constant in terms of certain parameters such as emergencyor elective surgery, accompanying diseases, newborn birth weight, and length ofstay in cases involving procedures and operations used in the diagnosis andtreatment of cardiovascular diseases.