Review
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Year 2019, Volume 1, Issue 1, 14 - 19, 19.08.2019
https://doi.org/10.38058/ijsl.594000

Abstract

References

  • Baral, B. 2017. Evolutionary trajectories of entomopathogenic fungi ABC transporters, Adv Genet, 98: 117-154.
  • Boumendjel, A., Boutonnat, J., Robert, J., 2009. ABC transporters and multidrug resistance. John Wiley & Sons Inc, Hoboken, New Jersey.
  • Cole, S.P., Deeley, G.R., 1998. Multidrug resistance mediated by the ATP‐binding cassette transporter protein MRP, Bioessays, 20 (11):931-940.
  • Cort, A., Ozben, T., Saso, L., De Luca, C., Korkina, L. 2016. Redox control of multidrug resistance and its possible modulation by antioxidants, Oxidative Medicine and Cellular Longevity, http://dx.doi.org/10.1155/2016/4251912
  • Dean, M., Rzhetsky, A., Allikmets, R. 2001. The human ATP-binding cassette (ABC) transporter superfamily, Genome Research, 11(7):1156-1166.
  • Domenichini, A., Adamska, A., Falasca, M. 2019. ABC transporters as cancer drivers, potential functions in cancer development, Biochim Biophys Acta Gen Subj, 1863(1): 52-60.
  • Flanagan, J.U., Huber, T. 2007. Structural evolution of the ABC transporter subfamily B, Evolutionary Bioinformatics, 3: 309–316.
  • Gupta, P., Zhang, Y. K., Zhang, X. Y., Wang, Y. J., Lu, K. W.,et al. Hall, T., 2018. Voruciclib, a potent CDK4/6 inhibitor, antagonizes ABCB1 and ABCG2-mediated multi-Drug resistance in cancer cells, Cell Physiol Biochem, 45(4): 1515-1528.
  • He, Q., Yan, Z., Si, F., Zhou, Y., Fu, W., et al. 2019. ATP-binding cassette (ABC) transporter genes involved in pyrethroid resistance in the malaria vector anopheles sinensis: Genome-wide identification, characteristics, phylogenetics, and expression profile, International Journal of Molecular Sciences, 20(6):1409.
  • Housman, G., Byler, S., Heerboth, S., Lapinska, K., Longacre, M., et al. 2014. Drug resistance in cancer, an overview, Cancers, 6(3): 1769-1792.
  • Erdamar, H., Hacıevliyagil Kazancı, F., Gök, S. 2014. Membrane biochemical changes in cancer, Journal of Clinical and Analytical Medicine, 5 (3): 430-438.
  • Ishiguro, J., Ito, H., Tsukamoto, M., Iwata, H., Nakagawa, H., & Matsuo, K. et al. 2019. A functional single nucleotide polymorphism in ABCC11, rs17822931, is associated with the risk of breast cancer in Japanese, Carcinogenesis, 40(4): 537-543.
  • Ji, J. Z., Tai, T., Huang, B. B., Gu, T. T., Mi, Q. Y., & Xie, H. G., 2018. Mrp3 transports clopidogrel acyl glucuronide from the hepatocytes into blood, Drug Metab Dispos, 46(2): 151-154.
  • Juliano, R.L., Ling, V. A. 1976. Surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants, Biochem, Biophys, Acta, 455:152–162.
  • Karva, S., 2014. The role of ABC transporters in anticancer drug transport, Turkish Journal of Biology, 38: 800-805.
  • Kathawala, R. J., Wang, Y. J., Ashby, C. R., Jr., Chen, Z. S. 2014. Recent advances regarding the role of ABC subfamily C member 10 (ABCC10) in the efflux of antitumor drugs, Chin J Cancer, 33(5): 223-230.
  • Lang Z, Wu Y, Pan X, Qu G, Zhang T. 2018. Study of differential gene expression between invasive mul¬tifocal/multicentric and unifocal breast cancer, JBUON, 23(1): 134-142.
  • Leonessa F., Clarke, R., 2003. ATP binding cassette transporters and drug resistance in breast cancer, Endocrine-Related Cancer, 10: 43–73.
  • Mansoori, B., Mohammadi, A., Davudian, S., Shirjang, S., Baradaran, B. 2017. The different mechanisms of cancer drug resistance: A brief review, Advanced Pharmaceutical Bulletin, 7(3): 339-348.
  • Pala Kara, Z., Öztürk, N., Öztürk, D, Okyar, A. 2013. ABC taşıyıcı proteinleri, sirkadiyan ritimler ve cinsiyete bağlı farklılıklar, Marmara Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 3(1):1-13.
  • Stavrovskaya, A.A., Stromskaya, T.P., 2008.Transport proteins of the ABC family and multidrug resistance of tumor cells, The Monthly Journal Biochemistry. (Moscow), 73:592-604.
  • Sharom, F.J., 2008. ABC multidrug transporters, structure, function and role in chemoresistance, Pharmacogenomics, 9(1):105–127.
  • Thoeringer, C. K., Wultsch, T., Shahbazian, A., Painsipp, E., & Holzer, P. 2007. Multidrug-resistance gene 1-type p-glycoprotein (MDR1 p-gp) inhibition by tariquidar impacts on neuroendocrine and behavioral processing of stress, Psychoneuroendocrinology, 32(8-10):1028-1040.

The effect of ATP-binding cassette (ABC) transporters in human cancers

Year 2019, Volume 1, Issue 1, 14 - 19, 19.08.2019
https://doi.org/10.38058/ijsl.594000

Abstract

Multi-drug resistance (MDR) can be defined as a negative effect on the drug-target relationships, decreasing in intracellular drug aggregation. ABC (ATP-binding cassette) are popular transporter proteins in the development of MDR. ABC proteins in the cell membrane structure reduce the therapeutic efficacy and cause drug resistance in cancer patients. Resistance to chemotherapy is a remarkable and important issue in the treatment of cancer patients. These drug resistance proteins interfere with the drugs administered to patients, resulting in a decrease in bioavailability of these drugs and a reduction in their passage through the blood-brain barrier. ABC transporters are the largest family of transmembrane proteins with 8 subfamilies assigned from A to G based on sequence and structural homology. In this review, general information about ABC proteins is mentioned and the role of ABC proteins causing MDR in cancers is also discussed. 

References

  • Baral, B. 2017. Evolutionary trajectories of entomopathogenic fungi ABC transporters, Adv Genet, 98: 117-154.
  • Boumendjel, A., Boutonnat, J., Robert, J., 2009. ABC transporters and multidrug resistance. John Wiley & Sons Inc, Hoboken, New Jersey.
  • Cole, S.P., Deeley, G.R., 1998. Multidrug resistance mediated by the ATP‐binding cassette transporter protein MRP, Bioessays, 20 (11):931-940.
  • Cort, A., Ozben, T., Saso, L., De Luca, C., Korkina, L. 2016. Redox control of multidrug resistance and its possible modulation by antioxidants, Oxidative Medicine and Cellular Longevity, http://dx.doi.org/10.1155/2016/4251912
  • Dean, M., Rzhetsky, A., Allikmets, R. 2001. The human ATP-binding cassette (ABC) transporter superfamily, Genome Research, 11(7):1156-1166.
  • Domenichini, A., Adamska, A., Falasca, M. 2019. ABC transporters as cancer drivers, potential functions in cancer development, Biochim Biophys Acta Gen Subj, 1863(1): 52-60.
  • Flanagan, J.U., Huber, T. 2007. Structural evolution of the ABC transporter subfamily B, Evolutionary Bioinformatics, 3: 309–316.
  • Gupta, P., Zhang, Y. K., Zhang, X. Y., Wang, Y. J., Lu, K. W.,et al. Hall, T., 2018. Voruciclib, a potent CDK4/6 inhibitor, antagonizes ABCB1 and ABCG2-mediated multi-Drug resistance in cancer cells, Cell Physiol Biochem, 45(4): 1515-1528.
  • He, Q., Yan, Z., Si, F., Zhou, Y., Fu, W., et al. 2019. ATP-binding cassette (ABC) transporter genes involved in pyrethroid resistance in the malaria vector anopheles sinensis: Genome-wide identification, characteristics, phylogenetics, and expression profile, International Journal of Molecular Sciences, 20(6):1409.
  • Housman, G., Byler, S., Heerboth, S., Lapinska, K., Longacre, M., et al. 2014. Drug resistance in cancer, an overview, Cancers, 6(3): 1769-1792.
  • Erdamar, H., Hacıevliyagil Kazancı, F., Gök, S. 2014. Membrane biochemical changes in cancer, Journal of Clinical and Analytical Medicine, 5 (3): 430-438.
  • Ishiguro, J., Ito, H., Tsukamoto, M., Iwata, H., Nakagawa, H., & Matsuo, K. et al. 2019. A functional single nucleotide polymorphism in ABCC11, rs17822931, is associated with the risk of breast cancer in Japanese, Carcinogenesis, 40(4): 537-543.
  • Ji, J. Z., Tai, T., Huang, B. B., Gu, T. T., Mi, Q. Y., & Xie, H. G., 2018. Mrp3 transports clopidogrel acyl glucuronide from the hepatocytes into blood, Drug Metab Dispos, 46(2): 151-154.
  • Juliano, R.L., Ling, V. A. 1976. Surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants, Biochem, Biophys, Acta, 455:152–162.
  • Karva, S., 2014. The role of ABC transporters in anticancer drug transport, Turkish Journal of Biology, 38: 800-805.
  • Kathawala, R. J., Wang, Y. J., Ashby, C. R., Jr., Chen, Z. S. 2014. Recent advances regarding the role of ABC subfamily C member 10 (ABCC10) in the efflux of antitumor drugs, Chin J Cancer, 33(5): 223-230.
  • Lang Z, Wu Y, Pan X, Qu G, Zhang T. 2018. Study of differential gene expression between invasive mul¬tifocal/multicentric and unifocal breast cancer, JBUON, 23(1): 134-142.
  • Leonessa F., Clarke, R., 2003. ATP binding cassette transporters and drug resistance in breast cancer, Endocrine-Related Cancer, 10: 43–73.
  • Mansoori, B., Mohammadi, A., Davudian, S., Shirjang, S., Baradaran, B. 2017. The different mechanisms of cancer drug resistance: A brief review, Advanced Pharmaceutical Bulletin, 7(3): 339-348.
  • Pala Kara, Z., Öztürk, N., Öztürk, D, Okyar, A. 2013. ABC taşıyıcı proteinleri, sirkadiyan ritimler ve cinsiyete bağlı farklılıklar, Marmara Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 3(1):1-13.
  • Stavrovskaya, A.A., Stromskaya, T.P., 2008.Transport proteins of the ABC family and multidrug resistance of tumor cells, The Monthly Journal Biochemistry. (Moscow), 73:592-604.
  • Sharom, F.J., 2008. ABC multidrug transporters, structure, function and role in chemoresistance, Pharmacogenomics, 9(1):105–127.
  • Thoeringer, C. K., Wultsch, T., Shahbazian, A., Painsipp, E., & Holzer, P. 2007. Multidrug-resistance gene 1-type p-glycoprotein (MDR1 p-gp) inhibition by tariquidar impacts on neuroendocrine and behavioral processing of stress, Psychoneuroendocrinology, 32(8-10):1028-1040.

Details

Primary Language English
Subjects Basic Sciences
Journal Section Review
Authors

Seda MESCİ> (Primary Author)
HITIT UNIVERSITY
0000-0002-5440-302X
Türkiye


Sevgi MARAKLİ>

0000-0001-5796-7819


Burak YAZGAN>

0000-0003-0717-7768


Tuba YILDIRIM>

0000-0001-8575-4802

Publication Date August 19, 2019
Published in Issue Year 2019, Volume 1, Issue 1

Cite

Bibtex @review { ijsl594000, journal = {International Journal of Science Letters}, eissn = {2687-4733}, address = {Amasya University, Central Research Laboratory, 05100 İpekköy-AMASYA}, publisher = {Amasya University}, year = {2019}, volume = {1}, number = {1}, pages = {14 - 19}, doi = {10.38058/ijsl.594000}, title = {The effect of ATP-binding cassette (ABC) transporters in human cancers}, key = {cite}, author = {Mesci, Seda and Marakli, Sevgi and Yazgan, Burak and Yıldırım, Tuba} }
APA Mesci, S. , Marakli, S. , Yazgan, B. & Yıldırım, T. (2019). The effect of ATP-binding cassette (ABC) transporters in human cancers . International Journal of Science Letters , 1 (1) , 14-19 . DOI: 10.38058/ijsl.594000
MLA Mesci, S. , Marakli, S. , Yazgan, B. , Yıldırım, T. "The effect of ATP-binding cassette (ABC) transporters in human cancers" . International Journal of Science Letters 1 (2019 ): 14-19 <https://dergipark.org.tr/en/pub/ijsl/issue/47946/594000>
Chicago Mesci, S. , Marakli, S. , Yazgan, B. , Yıldırım, T. "The effect of ATP-binding cassette (ABC) transporters in human cancers". International Journal of Science Letters 1 (2019 ): 14-19
RIS TY - JOUR T1 - The effect of ATP-binding cassette (ABC) transporters in human cancers AU - SedaMesci, SevgiMarakli, BurakYazgan, TubaYıldırım Y1 - 2019 PY - 2019 N1 - doi: 10.38058/ijsl.594000 DO - 10.38058/ijsl.594000 T2 - International Journal of Science Letters JF - Journal JO - JOR SP - 14 EP - 19 VL - 1 IS - 1 SN - -2687-4733 M3 - doi: 10.38058/ijsl.594000 UR - https://doi.org/10.38058/ijsl.594000 Y2 - 2019 ER -
EndNote %0 International Journal of Science Letters The effect of ATP-binding cassette (ABC) transporters in human cancers %A Seda Mesci , Sevgi Marakli , Burak Yazgan , Tuba Yıldırım %T The effect of ATP-binding cassette (ABC) transporters in human cancers %D 2019 %J International Journal of Science Letters %P -2687-4733 %V 1 %N 1 %R doi: 10.38058/ijsl.594000 %U 10.38058/ijsl.594000
ISNAD Mesci, Seda , Marakli, Sevgi , Yazgan, Burak , Yıldırım, Tuba . "The effect of ATP-binding cassette (ABC) transporters in human cancers". International Journal of Science Letters 1 / 1 (August 2019): 14-19 . https://doi.org/10.38058/ijsl.594000
AMA Mesci S. , Marakli S. , Yazgan B. , Yıldırım T. The effect of ATP-binding cassette (ABC) transporters in human cancers. IJSL. 2019; 1(1): 14-19.
Vancouver Mesci S. , Marakli S. , Yazgan B. , Yıldırım T. The effect of ATP-binding cassette (ABC) transporters in human cancers. International Journal of Science Letters. 2019; 1(1): 14-19.
IEEE S. Mesci , S. Marakli , B. Yazgan and T. Yıldırım , "The effect of ATP-binding cassette (ABC) transporters in human cancers", International Journal of Science Letters, vol. 1, no. 1, pp. 14-19, Aug. 2019, doi:10.38058/ijsl.594000