Multipl endocrine neoplasia type 1 (MEN1) is an autosomal dominant hereditary disease characterized by hyperplasia or hyperfunction in more than one endocrine gland. The parathyroid, pancreas and anterior pituitary are often affected. A 32-year-old female patient who applied to the endocrinology outpatient clinic was diagnosed with primary hyperparathyroidism due to hypercalcemia and accompanying elevation of parathyroidism while being followed up for nephrolithiasis. When etiological evaluation was performed, a parathyroid adenoma was observed in the lower right side outside the thyroid parenchyma in ultrasonographic evaluation, and involvement in the same location was observed in parathyroid scintigraphy. Lower right parathyroid adenomectomy was performed. Although the patient had no clinical findings, anterior pituitary hormone analyzes were performed as a MEN1 screening test because she was young. Insulin like growth factor -1 (IGF-1) level was high. The patient underwent an OGTT/GH suppression test, and the lowest growth hormone level was found to be 6.53 ng/dl. The patient was diagnosed with acromegaly. Transsphenoidal adenomectomy was performed on the patient, who was detected to have a macroadenoma in the pituitary MRI examination. During the postoperative follow-up of the patient, IGF-1 levels decreased to normal limits and no residual areas were detected. It is considered to be in remission and follow-up continues. Familial forms should be kept in mind in young cases of primary hyperparathyroidism. Screening for MEN1 may enable early diagnosis of accompanying neoplasias.