Deneysel Tıp Araştırma Enstitüsü Dergisi 2630-6050 Istanbul University Yeni Nesil DNA Dizileme Üstek Duran Abacı Neslihan Sırma Sema Çakiris Aris 10 25 2011 1 1 11 18 10 25 2011 Copyright © 2011, Deneysel Tıp Araştırma Enstitüsü Dergisi 2011 Deneysel Tıp Araştırma Enstitüsü Dergisi

Yeni nesil dizileme; genom, transkriptom, DNA-protein etkileşimlerinin geniş kapsamlı analizini ucuz, rutin ve yaygın hale dönüştürdüğünden biyolojik araştırmaları önemli ölçüde hızlandırma potansiyeline sahiptir. Yeni nesil dizileme teknolojisi; mRNA, küçük RNA profili, transkripsiyon faktör bağlanma bölgelerinin genom boyu karakterizasyonu, kromatin yapısı ve metilasyon paterni, atasal DNA mikrobiyolojisi ve metagenomik için yeni ve hızlı yollar sağlar. Bu makalede yeni nesil dizileme teknolojileri, yeni nesil dizileme sistemlerindeki yeni gelişmeler ve yeni nesil dizileme teknolojisinin uygulama alanları tartışılmıştır.

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