<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20241031//EN"
        "https://jats.nlm.nih.gov/publishing/1.4/JATS-journalpublishing1-4.dtd">
<article         dtd-version="1.4">
            <front>

                <journal-meta>
                                                                <journal-id>i̇st tıp fak derg</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Journal of Istanbul Faculty of Medicine</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">1305-6441</issn>
                                                                                            <publisher>
                    <publisher-name>Istanbul University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id/>
                                                                                                                                                                                            <title-group>
                                                                                                                        <article-title>FİBRAT KULLANIMINA BAĞLI RABDOMİYOLİZ GELİŞİMİ İLE İLİŞKİLİ AKUT BÖBREK YETERSİZLİĞİ</article-title>
                                                                                                                                        </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                <name>
                                    <surname>Yılmaz</surname>
                                    <given-names>Gülay</given-names>
                                </name>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Çavuş</surname>
                                    <given-names>Türker</given-names>
                                </name>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Çakır</surname>
                                    <given-names>Hasan</given-names>
                                </name>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Narlı</surname>
                                    <given-names>Erkan</given-names>
                                </name>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20111110">
                    <day>11</day>
                    <month>10</month>
                    <year>2011</year>
                </pub-date>
                                        <volume>74</volume>
                                        <issue>1</issue>
                                        <fpage>13</fpage>
                                        <lpage>14</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20111110">
                        <day>11</day>
                        <month>10</month>
                        <year>2011</year>
                    </date>
                                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 1916, Journal of Istanbul Faculty of Medicine</copyright-statement>
                    <copyright-year>1916</copyright-year>
                    <copyright-holder>Journal of Istanbul Faculty of Medicine</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Acil servisimize yaygın kas ağrısı, bulantı, kusma şikayetleri ile başvuran altmışiki yaşında kadın hastanın yapılan tetkiklerinde üre, kreatinin, aspartat aminotansferaz (AST), alanin aminotransferaz (ALT), kreatinkinaz (CK) değerlerinde yükseklik tespit edildi. Hasta akut böbrek yetersizliği tanısı ile yatırıldı. Diyabetes Mellitus (DM) Tip 2 ve hipertansiyon tanıları olan hasta lipid düşürücü tedavi amacıyla iki aydır günde 200 mg fenofibrat kullanmaktaydı. Son on gündür belirgin kas ağrıları vardı. Mevcut klinik ve laboratuar bulgularının eşliğinde hastada fenofibrat kullanımına bağlı rabdomiyolizin sebep olduğu akut böbrek yetersizliği tanısı konuldu. Fenofibrat tedavisi kesildi. İntravenöz sıvı tedavisi ve idrarı alkali yapmak amacıyla bikarbonat tedavisi uygulandı. Hastanın takiplerinde diyaliz ihtiyacı olmadı. Fizik muayene ve laboratuvar bulguları geriledi. Hasta poliklinik kontrolüne gelmek üzere çıkarıldı.</p></abstract>
                                                                                    
            
                                                            <kwd-group>
                                                    <kwd>Fenofibrat</kwd>
                                                    <kwd>   rabdomiyoliz</kwd>
                                                    <kwd>   akut böbrek yetersizliği</kwd>
                                            </kwd-group>
                                                        
                                                                                                                                                    </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">Bellomo R.The epidemiology of acute renal failure:1975 versus 2005. Curr Opin Crit Care. 2006;12:557- 560.</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">Clouatre Y, Leblanc M, Ouimet D, Pichette V. Fenofibrate induced rhabdomyolysis in two dialysis patients with hypothyroidism. Nephral Dial Transplant 1999;14:1047-1048.</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">Deighan CJ, Wong KM, Mclaughin KJ, Harden P. Rhabdomyolysis and acute renal failure resulting from alcohol and drug abuse. Q J Med 2000;93:29- 33.</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">Graham DJ , Staffa JA, Shatin D, Andrade SE, Schech SD, La Grenade L, Gurwitz JH, Chan KA, Goodman MJ, Platt R. Incidence of hospitalized rhabdomyolysis in patients treated with lipid lowering drugs. JAMA 2004 ;292:2585-2590.</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">Melli G, Chaundry V, Cornblath DR.Rhabdomyolysis ;an evaluation of 475 hospitalized patients.Medicine (Baltimore) 2005;84:377-385.</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">Nash K, Hafeez A, Hou S. Hospital acquired renal insufficiency. Am J Kidney Dis. 2002; 39:930-936.</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">Rosenson RS:Current overview of statin induced myopathy. Am J Med 2004;116:408-416.</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">Sauret JM, Marinidess G, Way Gordon K. Rhabdomyolysis. Am Fam Physician 2002;65:907- 912.</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">Vanholder M, Sever MS, Erek E, Lameine N, Acute renal failure related to crush syndrome:Toward on area of seismo nephrology? Nephrol Dial Transplant 2000;15:517-521</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
