Triterpenoids from Scorzonera veratrifolia Fenzl

Year 2018, Volume: 48 Issue: 2, 23 - 27, 31.08.2018

Betül Çetin Hasan Şahin , Aynur Sarı

Abstract

DOI:
10.5152/IstanbulJPharm.2018.410411

The genus Scorzonera (Asteraceae) has
several species which are used as a vegetable and in folk medicine all around
the world. A phytochemical study was carried out on petroleum ether fraction of
methanol extract obtained from the roots of Scorzonera veratrifolia Fenzl
(Bitlis / Turkey) to investigate the terpenoid composition of the plant. Column
chromatography, preparative thin layer chromatography and gas chromatography
(GC) were used for separation of the compounds. Their structures were
determined by using GC-MS and NMR techniques. Seventeen triterpenoids
(ß-amyrin, ß-amyrin acetate, ß-amyrinone, germanicol, germanicol acetate,
germanicone, α-amyrin, α-amyrin acetate, α-amyrinone, ψ – taraxasterol, ψ –
taraxasterol acetate, taraxasterol, taraxasterol acetate, lupeol, lupeol
acetate, lupenone, fern-7-en-3-one) and one sterol (ß-sitosterol) were
determined. The presence of these compounds has been shown for the first time
in S. veratrifolia. α-amyrinone, ß-amyrin, ß-amyrinone, ψ – taraxasterol and ψ
– taraxasterol acetate are new for the genus Scorzonera.

Keywords

Scorzonera veratrifolia, triterpenoids, sterol, GC-MS

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