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Yaşlılarda Depresyon ve Tekrarlayan Olumsuz Düşünce: Yürütücü İşlev Bozukluğunun Özgün Rolü

Year 2020, Volume: 40 Issue: 2, 561 - 578, 30.09.2020

Abstract

Yaşlılarda depresyon ciddi sonuçlara sebebiyet vermektedir, bu yüzden depresyona hassasiyet yaratan faktörleri anlamak, gerekli terapi yöntemlerinin geliştirilmesinde ve uygulanmasında faydalı olacaktır. Yaşlılıkta depresyona sebep olan risk faktörlerinden birisi yürütücü işlev bozukluklarıdır. Yürütücü işlevler üzerinde olumsuz etkisi olabilecek bir faktör geçmişte olmuş veya gelecekte olabilecek olaylara ilişkin kontrol edilemez, soyut, tekrarlayan ve genelde olumsuzluk içeren düşünme eğilimi olarak tanımlanan tekrarlayan olumsuz düşünce şeklidir. Bu araştırmanın amacı farklı yürütücü işlevlerin geriyatrik depresyon ve tekrarlayan olumsuz düşünce arasındaki ilişkide biçimlendirici etkisini araştırmaktır. Araştırmanın örneklemini 60-82 yaşları arasında 128 (63 kadın, 65 erkek) bağımsız yaşayan katılımcı oluşturmaktadır. Katılımcılara depresyon (Geriatrik Depresyon Ölçeği) ve tekrar eden düşünce eğilimini ölçen (Penn State Endişe Ölçeği) özbildirim ölçekleri ile inhibisyon (Stroop Renk-Kelime Testi) ve işler bellek kapasitesini ölçen (Sayı Dizisi Tersten) nöropsikolojik testler uygulanmıştır. Katılımcıların tamamı İstanbul’da ikamet etmektedir ve anadillerini Türkçe olarak belirtmişlerdir. Analizler, işler bellek kapasitesinin depresyon ve tekrarlayan olumsuz düşünce arasındaki ilişkiyi biçimlendirdiğini göstermiştir. Sonuçlara göre, düşük düzeyde tekrarlayan olumsuz düşünce gösteren katılımcılarda, işler bellek kapasitesinin depresyon üzerinde bir etkisi olmadığı bulunmuştur. Buna karşın, yüksek düzeyde tekrarlayan olumsuz düşünce gösteren yaşlılarda işler bellek kapasitesinin yüksek olması tekrarlayan olumsuz düşüncelerin olumsuz etkilerini yumuşattığı ve düşük depresyon puanları ile ilişkili olduğu belirlenmiştir. Ancak aynı biçimlendirici etki inhibisyon için bulunamamıştır. Elde edilen bulgular yaşlılıkta yüksek işler bellek kapasitesinin, depresyon ve tekrarlayan olumsuz düşünce arasındaki ilişkide tampon görevi üstlendiğini göstermiştir. Bu çalışmanın tekrarlayan olumsuz düşünce ve yütürücü işlev bozukluğunun da etkisiyle daha komplike bir hal alan geriyatrik depresyonun tedavisinde önemli bir yol gösterici olduğu düşünülmektedir.

References

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Depression and Repetitive Negative Thinking among Older Adults: The Specific Role of Executive Dysfunction

Year 2020, Volume: 40 Issue: 2, 561 - 578, 30.09.2020

Abstract

Depression in older adults poses serious consequences, thus understanding vulnerability factors may contribute to the development and implementation of appropriate clinical interventions. Executive function deficits have been proposed as risk factors for geriatric depression. One possible factor that may facilitate the impact of executive function deficits is Repetitive Negative Thinking (RNT) patterns that had been defined as an inclination to entertain uncontrollable, abstract, repetitive, and mainly negative thoughts about events that took place in the past or will take place in the future. The present study aimed to test the moderator roles of different dimensions of executive function on the relationship between repetitive negative thinking and geriatric depression. A sample of 128 community-dwelling older adults (63 women, 65 men), between 60 and 82 years of age, were administered both self-report questionnaires measuring depression (Geriatric Depression Scale), and repetitive negative thinking (Penn State Worry Questionnaire) and neuropsychological tests measuring inhibition (Stroop Color-Word Test) and working memory (Digit Span Backward). All participants lived independently in Istanbul, and spoke Turkish as their native language. The results showed that working memory capacity significantly moderated the relationship between repetitive negative thinking and depression as predicted. However, the results did not indicate the same moderator effect of inhibition. The present data suggests that high working memory capacity is able to moderate the relationship between repetitive negative thinking and depression among older adults. This finding has important implications for clinical interventions targeting depression in older adults whose clinical presentations are complicated with repetitive negative thinking and executive dysfunction.

References

  • Alexopoulos, G. S. (2003). The role of executive function in late-life depression. The Journal of Clinical Psychiatry, 64(14), 18-23.
  • Alexopoulos, G. S., Borson, S., Cuthberth, B. N., Devanand, D. P., Mulsant, B. H., Olin, J. T., & Oslin, D. W. (2002). Assessment of late life depression. Biological Psychiatry, 52(3), 164-174. https://doi.org/10.1016/S0006-3223(02)01381-1
  • Alexopoulos, G. S., Bruce, M. S., & Hull, J. (1999). Clinical determinants of suicidal ideation and behavior in geriatric depression. Archives of General Psychiatry, 56(11). 1048-1053. doi:10.1001/archpsyc.56.11.1048
  • Alexopoulos, G. S., Kiosses, D. N., Heo, M., Murphy, C. M., Shanmugham, B., & Gunning-Dixon, F. (2005). Executive dysfunction and the course of geriatric depression. Biological Psychiatry, 58(3), 204-210. https://doi.org/10.1016/j.biopsych.2005.04.024
  • Alexopoulos, G. S., Meyers, B. S., Young, R. C., Kalayam, B., Kakuma, T., Gabrielle, M., ... Hull, J. (2000). Executive dysfunction and long-term outcomes of geriatric depression. Archives of General Psychiatry, 57(3), 285-290. doi:10.1001/archpsyc.57.3.285
  • Bentler, P. M. (1990). Comparative fit indexes in structural models. Psychological Bulletin, 107(2), 238-246. http://dx.doi.org/10.1037/0033-2909.107.2.238
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  • Byrne, B. M. (2016). Structural equation modeling with AMOS: Basic concepts, applications, and programming. New York: Routledge.
  • Conwell, Y., Duberstein, P. R., & Caine, E. D. (2002). Risk factors for suicide in later life. Biological Psychiatry, 52(3), 193-204. https://doi.org/10.1016/S0006-3223(02)01347-1
  • Diamond, A. (2013). Executive functions. Annual Review of Psychology, 64, 135-168. https://doi.org/10.1146/annurev-psych-113011-143750
  • Doraiswamy, P. M., Khan, Z. M., Donahue, R. M. J., & Richard, N. E. (2002). The spectrum of quality-of-life impairments in recurrent geriatric depression. The Journals of Gerontology: Series A, 57(2), M134-M137. https://doi.org/10.1093/gerona/57.2.M134
  • Ehring, T., & Watkins, E. R. (2008). Repetitive negative thinking as a transdiagnostic process. International Journal of Cognitive Therapy, 1(3), 192-205. https://doi.org/10.1521/ijct.2008.1.3.192
  • Ertan, T., & Eker, E. (2000). Reliability, validity and factor structure of the geriatric depression scale in Turkish elderly: Are there different factor structures for different cultures? International Psychogeriatrics, 12(2), 163-162. https://doi.org/10.1017/S1041610200006293
  • Ertan, T., Eker, E., Güngen, C., Engin, F., Yaşar, R., & Kılıç, G., & Özel, S. (1999, August). The standardized mini mental state examination for illiterate Turkish elderly population. Paper presented at the 2nd International Symposium on Neurophysiological and Neuropsychological Assessment of Mental and Behavioral Disorders, Bursa, Turkey.
  • Ertan, T., Eker, E., & Şar, V. (1997). Reliability and validity of the geriatric depression scale in Turkish elderly population. Archives of Neuropsychiatry (Turkish), 34(1), 62-71.
  • Fischer, C., Schweizer, T. A., Atkins, J. H., Bozanovic, R., Norris, M., Herrmann, N., ... Rourke, S. B. (2008). Neurocognitive profiles in older adults with and without major depression. International Journal of Geriatric Psychiatry, 23, 851-856. https://doi.org/10.1002/gps.1994
  • Fiske, A., Wetherell, J. L., & Gatz, M. (2009). Depression in older adults. Annual Review of Clinical Psychology, 5, 363-389. https://doi.org/10.1146/annurev.clinpsy.032408.153621
  • Friedman, N. P., & Miyake, A. (2004). The relations between inhibition and interference control functions: A latent-variable analysis. Journal of Experimental Psychology: General, 133(1), 101-135. doi: 10.1037/0096-3445.133.1.101
  • Friedman, N. P., & Miyake, A. (2017). Unity and diversity of executive functions: Individual differences as a window on cognitive structure. Cortex, 86, 186-204. https://doi.org/10.1016/j.cortex.2016.04.023
  • Gathercole, S. E. (1994). Neuropsychology and working memory: A review. Neuropsychology, 8(4), 494-505. Gazzaley, A., Cooney, J. W., Rissman, J., & D’Esposito, R. (2005). Top-down suppression deficit underlies working memory impairment in normal aging. Nature Neuroscience, 8, 1298-1300. doi:10.1038/nn1543
  • Golden, C. J. (1978). Stroop Color and Word Test. A Manual for Clinical and Experimental Uses. Illinois: Stoelting Company.
  • Güngen, C., Ertan, T., Eker, E., Yaşar, R., & Engin, F. (2002). Reliability and validity of the standardized Mini Mental State Examination in the diagnosis of mild dementia in Turkish population. Turkish Journal of Psychiatry (Turkish), 13(4), 273-281.
  • Hasher, L., Quig, M. B., & May, C. P. (1997). Inhibitory control over no-longer-relevant information: Adult age differences. Memory & Cognition, 25(3), 286-295. https://doi.org/10.3758/BF03211284
  • Hayes, A.F. (2013). Introduction to mediation, moderation, and conditional process analysis: A regression-based approach. New York: The Guilford Press.
  • Hayes, S., Hirsch, C., & Matthews, A. (2008). Restriction of working memory capacity during worry. Journal of Abnormal Psychology, 117(3), 712-717. http://dx.doi.org/10.1037/a0012908
  • Hu, L., & Bentler, P. M. (1999). Cutoff criteria for fit indexes in covariance structure analysis: Conventional criteria versus new alternatives. Structural Equation Modeling, 6(1), 1-55. https://doi.org/10.1080/10705519909540118
  • Hu, L., Bentler, P. M., & Kano, Y. (1992). Can test statistics in covariance structure analysis be trusted? Psychological Bulletin, 112(2), 351-362.
  • Hubbard, N. A., Hutchison, J. L., Hambrick, D. Z., & Rypma, B. (2016). The enduring effects of depressive thoughts on working memory. Journal of Affective Disorders, 190, 208-213. https://doi.org/10.1080/02699931.2014.991694
  • Joormann, J., & Gotlib, I. H. (2010). Emotion regulation in depression: relation to cognitive inhibition. Cognition and Emotion, 24(2), 281-298. https://doi.org/10.1080/02699930903407948
  • Joormann, J., Siemer, M., & Gotlib, I. H. (2007). Mood regulation in depression: Differential effects of distraction and recall of happy memories on sad mood. Journal of Abnormal Psychology, 116, 484–490. doi:10.1037/0021-843X.116.3.484
  • Kalayam, B., & Alexopoulos, G. S. (1999). Prefrontal dysfunction and treatment response in geriatric depression. Archives of General Psychiatry, 56(8), 713-718. doi:10.1001/archpsyc.56.8.713
  • Karakaya, M. G., Bilgin, S. Ç., Ekici, G., Köse, N., & Otman, A. S. (2009). Functional mobility, depressive symptoms, level of independence, and quality of life of the elderly living at home and in the nursing home. Journal of the American Medical Directors Association, 10(9), 662-666. doi.org/10.1016/j.jamda.2009.06.002
  • Kerem, M., Meriç, A., Kırdı, N., & Cavlak, U. (2001). Evaluation of elderly living at home and rest house. Turkish Journal of Geriatrics, 4(3), 106-112.
  • Kline, R. B. (1998). Principles and practices of structural equation modeling. New York: Guilford.
  • Koster, E. H., De Lissnyder, E., Derakshan, N., & De Raedt, R. (2011). Understanding depressive rumination from a cognitive science perspective: The impaired disengagement hypothesis. Clinical Psychology Review, 31(1), 138-145. https://doi.org/10.1016/j.cpr.2010.08.005
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There are 58 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Yasemin Sohtorik This is me 0000-0002-9479-4942

Ayşe Altan-atalay This is me 0000-0001-9748-2517

Publication Date September 30, 2020
Submission Date October 1, 2020
Published in Issue Year 2020 Volume: 40 Issue: 2

Cite

APA Sohtorik, Y., & Altan-atalay, A. (2020). Depression and Repetitive Negative Thinking among Older Adults: The Specific Role of Executive Dysfunction. Studies in Psychology, 40(2), 561-578.
AMA Sohtorik Y, Altan-atalay A. Depression and Repetitive Negative Thinking among Older Adults: The Specific Role of Executive Dysfunction. Studies in Psychology. September 2020;40(2):561-578.
Chicago Sohtorik, Yasemin, and Ayşe Altan-atalay. “Depression and Repetitive Negative Thinking Among Older Adults: The Specific Role of Executive Dysfunction”. Studies in Psychology 40, no. 2 (September 2020): 561-78.
EndNote Sohtorik Y, Altan-atalay A (September 1, 2020) Depression and Repetitive Negative Thinking among Older Adults: The Specific Role of Executive Dysfunction. Studies in Psychology 40 2 561–578.
IEEE Y. Sohtorik and A. Altan-atalay, “Depression and Repetitive Negative Thinking among Older Adults: The Specific Role of Executive Dysfunction”, Studies in Psychology, vol. 40, no. 2, pp. 561–578, 2020.
ISNAD Sohtorik, Yasemin - Altan-atalay, Ayşe. “Depression and Repetitive Negative Thinking Among Older Adults: The Specific Role of Executive Dysfunction”. Studies in Psychology 40/2 (September 2020), 561-578.
JAMA Sohtorik Y, Altan-atalay A. Depression and Repetitive Negative Thinking among Older Adults: The Specific Role of Executive Dysfunction. Studies in Psychology. 2020;40:561–578.
MLA Sohtorik, Yasemin and Ayşe Altan-atalay. “Depression and Repetitive Negative Thinking Among Older Adults: The Specific Role of Executive Dysfunction”. Studies in Psychology, vol. 40, no. 2, 2020, pp. 561-78.
Vancouver Sohtorik Y, Altan-atalay A. Depression and Repetitive Negative Thinking among Older Adults: The Specific Role of Executive Dysfunction. Studies in Psychology. 2020;40(2):561-78.

Psikoloji Çalışmaları / Studies In Psychology / ISSN- 1304-4680