Correlation between Phenolic Composition and Biological Properties of Propolis and Heavy Metal Contents

Year 2018, Volume: 1 Issue: 3 - 2nd Propolis Conference Special Issue, 46 - 46, 08.12.2018

María İnmaculada González-martín Eddy Valentín Betances-salcedo İsabel Revılla Ana María Vıvar-quıntana

Abstract

The presence of heavy metals in propolis is
associated with the environmental pollution of anthropic origin around the apiaries
via various sources such as air, water, plants and soil. Although the presence
of these compounds could affect the biological properties of the propolis, the
correlation between them has not been previously studied. Then, the aim of this
work was to stablish the correlations between the levels of some heavy metals
such as lead, chromium, nickel, copper or zinc and phenolic composition and
biological properties such as antioxidant or antibacterial activities. For this
work, 44 propolis samples of different geographic locations were analyzed:
Chile (Biobio region n=10) and Spain (Galicia n=12 and Castilla y León n=22).
The mineral composition analysis was performed using ICP-MS (Inductively
Coupled Plasma Mass Spectrometry). Antioxidant activity was measured using
ABTS, DPPH and inhibiting activity of the linoleic acid/-caroten radical
assays. Phenolic acids and their derivatives were determined by HPLC and
biocide properties using the Five-Plate test. Pearson correlations were
calculated with SPSS statistic package.

            The
results show a negative correlation between antibacterial activity similar to
betalactamic antibiotics with nickel (p<0.01) and chromium (p<0.01)
levels. The lead content was negatively correlated with phenolic acids and
their derivatives. This correlation was statistically significant for the
cynamil capheoil ester (p<0.05). The zinc and copper contents were
positively correlated with cumaric acid and cinnamic derivatives (p<0.05)
respectively. Heavy metal levels were in general negatively correlated with
antioxidant activity and these correlations were significant for copper
(p<0.05) and lead (p<0.01).

Keywords

Propolis, Heavy metal content, Phenolic Composition

References

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