Isolated Triterpenes from Stingless Bee Lisotrigona furva Propolis in Vietnam

Year 2018, Volume: 1 Issue: 3 - 2nd Propolis Conference Special Issue, 73 - 73, 08.12.2018

Le Nguyen Thanh Vu Thi Kim Oanh Ha Thi Thoa Diep Thi Lan Phuong Nguyen Thi Phuong Lıen Tran Huu Gıap Nguyen Thi Minh Hang Nguyen Van Hung Vassya Bankova

Abstract

Stingless bees of the genus Lisotrigona
are uncommon species found in India and South East Asian countries. Several Lisotrigona
species including L. cacciae, L.carpenteri and L. furva from
Vietnam have been described. There has been no information on the chemical
constituents and bioactivity of Lisotrigona stingless bee propolis in
Vienam. Our goal of this work is to investigate the chemical constituents of
the stingless bee Lisotrigona furva propolis collected in Binhdinh
province, Vietnam. Using combined chromatographic methods, several triterpenes
including mangiferolic acid (1), occotilones I (2) and II (3),
dipterocarpol (4), hydroxyhopanone (5) and (13E,17E)-polypoda-7,13,17,21-tetraen-3β-ol
(6) were isolated from the ethyl acetate extract of Lisotrigona furva
propolis. The chemical structures of isolated compounds were identified by
MS, NMR spectral analysis. Compound 5 and 6 were isolated for the first
time from stingless bee propolis.

Acknowledgements: This research is
funded by Vietnam Academy of Science and Technology under grant number
VAST.HTQT.BULGARIA.02/17-18. 

Keywords

Lisotrigona furva propolis, NMR

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