A Review on The Development, Production Strategies, and Utilization of Monoclonal Antibodies

Year 2020, Volume: 4 Issue: 3, 197 - 204, 01.09.2020

Gamze Sanlav Ömer Bekçioğlu Yasemin Başbınar

Abstract

Over the last 20 years, monoclonal antibodies have become the backbone of biological therapeutics for the treatment and diagnosis of several
diseases. The rising incidence of cancer and other immunologic diseases promoted the increasing investments of the global pharmaceutical
industry in monoclonal antibody development. The R&D has focused on the highest efficacy which is majorly correlated with the antigenbinding
specificity and the lowest immunogenicity of monoclonal antibodies. This review aims to provide a brief description and explanation
of each stage in the development path of mAbs.
Keywords: monoclonal antibodies, industry, cancer

Keywords

monoclonal antibodies, industry, cancer

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