Investigation of Parvovirus B19 IgG and IgM antibodies with ELISA, distribution with regard to age groups and comparison with literature

Year 2018, Volume: 9 Issue: 1, 30 - 33, 10.03.2018

Ayşe İnci Aytül Çorbacıoğlu Esmer

https://doi.org/10.5799/jcei.413067

Abstract

Investigation
of Parvovirus B19 IgG and IgM antibodies with ELISA, distribution with regard
to age groups and comparison with literature

Ayşe İnci,
Aytül Çorbacıoğlu Esmer

 

Objective:
Human
parvovirus is an un-enveloped, linear, single bundle DNA virus 18-26 nm in
diameter which is common worldwide and causes an asymptomatic infection. The
most common clinical manifestation is erythema infectiosum, it may also lead to
aplastic crisis, arthropathy, neutropenia, thrombocytopenia and fetal
infections. In this study, we aimed to determine parvovirus B19 sero-positivity
rates, distribution according to age and contribute to epidemiologic data in
our country.

Patients
and Methods: Results
of pregnant women who were admitted to Kanuni Suleiman Hospital between January
2015 and January 2017, examined for parvovirus B19 infection and whose
parvovirus B19 IgG/IgM antibodies were examined with ELISA method were recorded
from patient files. Parvovirus B19 IgM and parvovirus B19 IgG test results were
retrospectively analyzed. parvovirus B19 IgM and parvovirus B19 IgG were
examined with ELISA method in accordance with recommendations of the
manufacturer.

Results:
A total of 156
pregnant women whose parvovirus B19 IgG/IgM antibodies had been analyzed were
included in the study. While parvovirus B19 IgG was positive in 64.7% of the
patients, parvovirus B19 IgM alone positivity was not detected in any women.
parvovirus B19 IgG and IgM were positive in 3 women. parvovirus B19 IgG
positivity was greatest above 40 years and minimum in 18-25 age group.

Conclusion:
In conclusion,
parvovirus B19 IgG positivity was found similar with that in other countries.
We consider that studies conducted with different groups and in different
regions would contribute to epidemiologic data.

Keywords

Parvovirus B19, pregnancy, ELISA

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