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            <front>

                <journal-meta>
                                    <journal-id></journal-id>
            <journal-title-group>
                                                                                    <journal-title>Çocuk Dergisi</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">1308-8491</issn>
                                                                                            <publisher>
                    <publisher-name>Istanbul University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.5222/j.child.2011.043</article-id>
                                                                                                                                                                                            <title-group>
                                                                                                                        <article-title>Anafilaksi ve Anafilaksideki Gelişmeler</article-title>
                                                                                                                                                                                                <trans-title-group xml:lang="en">
                                    <trans-title>Anaphylaxis and Advances in Anaphylaxis</trans-title>
                                </trans-title-group>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                <name>
                                    <surname>Bostancı</surname>
                                    <given-names>İlknur</given-names>
                                </name>
                                                                    <aff>Dr. Sami Ulus Kadın Doğum, Çocuk Sağlığı ve Hastalıkları Eğitim  ve Araştırma Hastanesi Çocuk Allerji Kliniği</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Doğru</surname>
                                    <given-names>Mahmut</given-names>
                                </name>
                                                                    <aff>Dr. Sami Ulus Kadın Doğum, Çocuk Sağlığı ve Hastalıkları Eğitim  ve Araştırma Hastanesi Çocuk Allerji Kliniği</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20110401">
                    <day>04</day>
                    <month>01</month>
                    <year>2011</year>
                </pub-date>
                                        <volume>11</volume>
                                        <issue>2</issue>
                                        <fpage>43</fpage>
                                        <lpage>53</lpage>
                        
                        <history>
                                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2000, Journal of Child</copyright-statement>
                    <copyright-year>2000</copyright-year>
                    <copyright-holder>Journal of Child</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Anafilaksi, ani başlayan ve ölüme yol açabilen ciddi siste- mik bir hipersensitivite reaksiyonudur. Anafilaksi klinik bir  acildir. Anafilaksi insidansı özellikle yaşamın ilk iki deka- dında artmaktadır. Yaygın olan tetikleyiciler besinler, ilaç- lar ve böcek sokmalarıdır. Tanısı primer olarak klinik kri- terlere dayanır. Bazı hastalarda anafilaksi tanısı kan test- leri  artmış histamin ve total triptaz düzeyi gibi  ile doğru- lanabilir. Fakat bu testler anafilaksi için spesifik değildir.  Adrenalin anafilaksi tedavisinde ilk seçenek ilaçtır.  Hastalar taburcu edilirken adrenalin otoenjektörü reçete  edilmeli ve kullanımının eğitimi verilmelidir. Bu makalede  anafilaksinin patogenezi, kliniği, tanı ve yeni tedavi yön- temleri sunulmuştur</p></abstract>
                                                                                                                                    <trans-abstract xml:lang="en">
                            <p>Anaphylaxis is a serious hypersensitivity reaction with a  rapid onset which might eventually lead to death.  Anaphylaxis is a clinical emergency. The incidence anaph- ylaxis is increasing, particularly during the first 2 decades  of life. Common triggers include foods, medications, and  insect stings. Its diagnosis is based primarily on clinical  criteria. In some patients the clinical diagnosis of anaph- ylaxis can be confirmed by means of a blood test  i.e., an  increased plasma histamine or serum total tryptase level  .  However, these tests are not specific for anaphylaxis.  Adrenaline is the first choice medication in the treatment of  anaphylaxis. On discharge from hospital, an autoinjectible  epinephrine should be prescribed and appropriate should  be providd about its use In this review pathogenesis, clini- cal features, diagnosis and new treatment modalities of  anaphylaxis were presented</p></trans-abstract>
                                                            
            
                                                            <kwd-group>
                                                    <kwd>Anafilaksi</kwd>
                                                    <kwd>  tanı</kwd>
                                                    <kwd>  tedavi</kwd>
                                                    <kwd>  adrenalin otoenjektör</kwd>
                                            </kwd-group>
                                                        
                                                                            <kwd-group xml:lang="en">
                                                    <kwd>Anaphylaxis</kwd>
                                                    <kwd>  diagnosis</kwd>
                                                    <kwd>  treatment</kwd>
                                                    <kwd>  adrenaline autoinjector</kwd>
                                            </kwd-group>
                                                                                                            </article-meta>
    </front>
    <back>
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