Çocuk Dergisi

1308-8491

Istanbul University

Çocuklarda Atopik Dermatit

Atopic Dermatitis in Children

Giniş

Tayfur

Sağlık Bakanlığı Dr. Sami Ulus Kadın Doğum, Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi Çocuk Alerji Kliniği

04 01 2009

9 2 62 67

2000

Journal of Child

Atopik dermatit çoğunlukla solunum yolu alerjileri ile ilişkili, kronik, yineleyen, kaşıntılı inflamatuvar bir deri hastalığıdır. Son 30 yılda prevelansı sanayileşmiş ülkelerde iki ya da üç kat artmıştır. Hastalığın etiyolojisi tam olarak bilinmemesine rağ- men, gen-gen ve gen çevre etkileşimlerinden kaynaklandığı düşünülmektedir. Bu makalede atopik dermatitin patogenezi, kliniği, tanı ve yeni tedavi yöntemleri sunulmuştur

Atopic dermatitis is a chronically relapsing inflammatory pruritis disease commonly associated with respiratory allergy. The prevalence of disease has doubled or tripled in industria- lized countries during the past three decades. Although etio- logy of disease is not completely understood, it is considered that the disease arises from gene-gene and gene-environment interactions. In this review pathogenesis, clinical features, diagnosis and new treatment modalities of atopic dermatitis were presented

Atopik dermatit patogenez tanı tedavi

Atopic dermatitis pathogenesis diagnosis treatment

1. Leung AK, Hon KL, Robson WL. Atopic dermatitis. Adv Pediatr 2007; 54:241-73.

2. Spergel JM, Paller AS. Atopic dermatitis and the atopic march. J Allergy Clin Immunol 2003; 112:118-27.

3. Akdis CA, Akdis M, Bieber T, et al. Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report. J Allergy Clin Immunol 2006; 118:152-69.

4. Boguniewicz M, Leung DY. Atopic dermatitis. Middleton’s Allergy: Principles and Practice; 7th Ed. China Elsevier 2009: 1083-9.

5. Ong PY, Boguniewicz M. Atopic dermatitis. Prim Care 2008; 35:105-17.

6. Thomas B. Atopic dermatitis. N Engl J Med 2008; 358:1483-94.

7. Novak N. New insights into the mechanism and management of allergic diseases: atopic dermatitis. Allergy 2009; 64:265- 75.

8. Werfel T, Ballmer-Weber B, Eigenmann PA, et al. Eczematous reactions to food in atopic eczema: position paper of the EAACI and GALEN. Allergy 2007; 62:723-8.

9. Hill DJ, Hosking CS, de Benedictis FM, et al. Confirmation of the association between high levels of immunoglobulin E food sensitization and eczema in infancy: an international study. Clin Exp Allergy 2008; 38:161-8.

10. Boralevi F, Hubiche T, Léauté-Labrèze C, et al. Epicutaneous aeroallergen sensitization in atopic dermatitis infantsdetermining the role of epidermal barrier impairment. Allergy 2008; 63:205-10.

11. Baumer JH. Guideline review: atopic eczema in children, NICE. Arch Dis Child 2008.

12. Wasserbauer N, Ballow M. Atopic dermatitis. Am J Med 2009; 122(2):121-5.

13. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol (Stockh) 1980; 92(Suppl):44-7.

14. Krakowski AC, Eichenfield LF. Management of atopic dermatitis in the pediatric population. Pediatrics 2008; 122:812- 24.

15. Greer FR, Sicherer SH, Burks AW, et al. Effects of early nutritional interventions on the development of atopic disease in infants and children: the role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods, and hydrolyzed formulas. Pediatrics 2008; 121:183-91.

16. Jung T, Stingl G. Atopic dermatitis: therapeutic concepts evolving from new pathophysiologic insights. J Allergy Clin Immunol 2008; 122:1074-81.

17. Sicherer SH, Leung DY. Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2008. J Allergy Clin Immunol 2009; 123:319- 27.

18. Leung DY. Nelson Textbook of Pediatrics 18h edition Elsevier 2009: 971-5