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Pasif Sigara İçiciliğinin Çocuklarda Aterosklerotik Risk Faktörlerine Etkisi

Year 2012, Volume: 12 Issue: 1, 24 - 29, 01.01.2012
https://doi.org/10.5222/j.child.2012.024

Abstract

Amaç: Çevresel sigara dumanının karotis arter intimal medial kalınlık ölçümlerine, kan lipid, lipoprotein düzeyleri ve kan basıncı üzerine etkisini ortaya koymak. Yöntemler: On dört-15 yaş grubuna giren ve evde kronik olarak pasif sigara dumanına maruz kalan 20 kız 20 erkek vakada karotis arter intimal medial kalınlığı, serum total kolesterol, LDL-C, HDL-C, VIDL-C, trigliserid düzeyleri ve kan basınçları ölçülerek aynı yaş grubundan 20 kız ve 20 erkekten oluşan kontrol grubuyla karşılaştırıldı. Bulgular: Pasif sigara dumanına maruz kalan grupta karotis arter intimal medial kalınlık ölçüm sonuçları, serum ortalama total kolesterol ve LDL-C düzeyleri anlamlı derecede daha yüksek, serum HDL-C düzeyleri anlamlı derecede düşük bulundu. Vakaların tümünde açlık kan glikoz düzeyleri normal sınırlarda bulundu. Pasif sigara dumanına maruz kalan grubun ortalama hem sistolik hem de diastolik kan basıncı değerleri anlamlı derecede yüksek bulundu. Ejeksiyon fraksiyon düzeylerinde ise anlamlı bir farklılık saptanmadı. Sonuç: Pasif sigara içiciliği karotis aterosklerozunda önemli bir risk faktörü olabilir

References

  • Lynch J, Krause N, Kaplan GA, Salonen R, Salonen J. Workplace demands, economic rewards and progression of carotid atherosclerosis. Circulation 1997;96:302-7. http://dx.doi.org/10.1161/01.CIR.96.1.302 PMid:9236449
  • Holman RL, Mc Gill HC, Strong JP, Geer JC. The natural history of atherosclerosis. Am J Pathol 1958;34:209-35. PMid:13520905 PMCid:1934740
  • Strong JP, Mc Gill HC Jr. The pediatric aspects of atherosc- lerosis. J Atheroscler Res 1969;9:251-65. http://dx.doi.org/10.1016/S0368-1319(69)80020-7
  • Bao W, Srinivasan RS, Valdez R, Greenlund JK, Wattlihney AW, Berenon SG. Longitudinal changes in cardiovascular risk from childhood to young adulthood in offspring of parents with coronary artery disease: The Bogalosa Heart Study. JAMA 1997;278:1749-54. http://dx.doi.org/10.1001/jama.1997.03550210047037
  • Bush PJ, Zuckerman AE, Theiss PK, Taggart VS, Horowitz C, Sheridon MJ. Walter HJ. Cardiovascular risk factor pre- vention in black schoolchildren: two year results of the “Know Your Body” program. Am J Epidemiol 1989;129:466-82. PMid:2916540
  • Bush PJ, Zuckerman AE, Taggart VS, Theiss PK, Peleg EO, Smith SA. Cardiovascular risk factor prevention in black school children: the “Know Your Body” evaluation project. Health Educ Q 1989;16:215-27. http://dx.doi.org/10.1177/109019818901600206
  • Fuster V, Badimon L, Bedimon JJ, Chesebro JH. The pat- honegesis of coronary artery disease and the acute coronary syndromes. N Engl J Med 1992;326:242-50. http://dx.doi.org/10.1056/NEJM199201233260406 PMid:1727977
  • Surgeon Generol. The Health Consequences of Smoking: CardiovascularDisease: A report of the surgeon General: Rockwille, Md US PublicHealth Service, Dept of Healthand Human Services, 1983.
  • Dwyer JH. Exposure to environmental tobacco smoke and coronary risk. Circulation 1997;96:1367-9. PMid:9315516
  • Garland C, Barrett-Connor E, Suarez L, Criqui MH, Wingard DL. Effects of passive smoking on ischemic heart disease mortality of non-smokers. A prospective study. Am J Epidemiol 1985;121:645-9. http://dx.doi.org/10.1093/aje/121.5.645 PMid:4014156
  • Gidding SS, Morgan W, Perry C, Jones JI, Bricker JT. Active and passive tobacco exposure: A serious pediatric health problem. A statement from the committee and atherosc- lerosis and hypertension in children, council on cardiovascular disease in the young, American Heart Association Circulation 1994;90:2581-90.
  • Hacettepe Halk Sağlığı Vakfı: Sigara içme konusundaki dav- ranışlar ve tutumlar Ankara / Türkiye: Özet rapor, 1997.
  • Crofton J. Tobacco: A future disaster for Turkey’s children. Turk J Pediatr 1996;38:1-11.
  • Hausberg M, Mark AL, Winniford MD, Brown RE, Somers VK. Sympathetic and vascular effects of short-term passive smoke exposure in healthy non-smokers. Circulation PMid:9236446
  • He Y, Lam TH, Li LS, Du RY, Jia GL, Huang JY, Zheng JS. Passive smoking at work as a risk factor for coronary heart disease in Chinese women who never smoked. BMJ 1994;308:380-4. http://dx.doi.org/10.1136/bmj.308.6925.380 PMid:8124145 PMCid:2539443
  • Howard G, Wagenknecht LE, Burke GL, Diez- Roux A, Evans GW, McGovern P, Nieto FJ, Tell GS. Cigarette smo- king and progression of atherosclerosis: The Atheroscleros is Risk In Commununities (ARIC) Study. JAMA 1998;279:119- 24. http://dx.doi.org/10.1001/jama.279.2.119
  • Moscıwitz WB, Mosteller M, Schieken RM, Bossano R, Hewitt JK, Bodurtha JN, Segrest JP. Lipoprotein and oxy- gen transport alteration in passive smoking preadolescent children. The MCV twin study. Circulation 1990;81:586-92. http://dx.doi.org/10.1161/01.CIR.81.2.586 PMid:2297864
  • Yamasaki Y, Kawamori R, Matsushima H, Nishizawa H, Kodama M, Kajimato Y, Morishima T, Kamada T. Atherosclerosis in carotidartery of young IDDM patients monitored by ultrasound high-resolution B-mode imaging. Diabetes 1994;43:634-9. http://dx.doi.org/10.2337/diabetes.43.5.634 PMid:8168638
  • National Council Research Council. Enviromental tobacco smoke measuring exposure and assesing health effects. Washington DC. National Academy Press 1996
  • Glantz SA, Parmley WW. Passive smoking and heart disea- se. Mechanisms and risk. JAMA 1995;273:1047-53. http://dx.doi.org/10.1001/jama.1995.03520370089043
  • Lightwood JM, Gliantz SA. Short-term economic and health benefits of smoking cessation: myocardial infarction and stro- ke. Circulation 1997;96:1089-96. http://dx.doi.org/10.1161/01.CIR.96.4.1089 PMid:9286934
  • Steenland K. Passive smoking and the risk of heart disease. JAMA 1992;267:94-9. http://dx.doi.org/10.1001/jama.1992.03480010102033
  • Chambless LE, Folsom AR, Davis V, Sharrett R, Heiss G, Sorlie P, Szklo M, Howard G, Evans GW. Risk factors for progression of common carotid atherosclerosis: the Atherosclerosis Risk in Communities Study, 1987-1998. Am J Epidemiol 2002;155:38-47. http://dx.doi.org/10.1093/aje/155.1.38 PMid:11772783
  • Homer D, Ingail TJ, Baker HL, O’Fallon WM, Kottke BA, Whisnant JP. Serum lipids and lipoproteins are less powerful predictors of extracranial carotid artery atherosclerosis than are cigarette smoking and hypertension. Mayo Clin Proc 1991;66:259-67. PMid:2002684
  • Celermajer DS, Adams MR, Clarkson P, Robinson J, McCredie R, Donald A, Deanfield JE. Passive smoking and impaired endothelium-dependent arterial dilatation in healthy young adults. N Engl J Med 1996;334:150-4. http://dx.doi.org/10.1056/NEJM199601183340303 PMid:8531969
  • Howard G, Burke GL, Szklo M, Tell GS, Eckfeldt J, Evans G, Heiss G. Active and passive smoking are associated with increased carotid wall thickness. The athe-rosclerosis risk in communities study. Arch Intern Med 1994;154:1277-82. http://dx.doi.org/10.1001/archinte.1994.00420110125014 PMid:8203995
  • Craig WY. Palomaki GE, Johnson AM, Haddow JE. Cigarette smoking associated changes in blood lipid and lipoprotein levels in the 8 to 19-year old group a meta- analysis. Pediatrics 1990;85:155-8. PMid:2136949
  • Feldman J, Shenker I, Etzel RA, Spierto FW, Lilienfield DE, Nussbaum M, Jacobson MS. Passive smoking alters lipid profiles in adolescents. Pediatrics 1991;88:259-64. PMid:1861923
  • Freedman DS, Srinivasan SR, Shear CL, Hunter SM, Craft JB, Webber LS, Berenson GS. Cigarette smoking initiaition and longitudinal changes in serum lipids and lipop- roteins in early adulthood. The Bogalosa Heart Study. Am J Epidemiol 1986;124:207-19. PMid:3728437
  • Diez- Roux AV, Nieto FJ, Comstock GW, Howard G, Szklom M. The relationship of active and passive smoking to carotid atherosclerosis 12-14 years later. Press Med 1995;24:48-55.
  • Nagel G, Arnold FJ, Wilhelm M, Link B, Zoellner I, Koenig W. Environmental tobacco smoke and cardiometabo- lic risk in young children: results from a survey in south-west Germany. Eur Heart J 2009;30:1885-93. http://dx.doi.org/10.1093/eurheartj/ehp180
  • Zielińska-Danch W, Wardas W, Sobczak A, Szołtysek- Bołdys I. Estimation of urinary cotinine cut-off points distin- guishing non-smokers, passiveand active smokers. Biomarkers http://dx.doi.org/10.1080/13547500701421341 PMid:17701747
  • Chen LC, Quan C, Hwang JS, Jin X, Li Q, Zhong M, Rajagopalan S, Sun Q. Atherosclerosis lesion progression during inhalation exposure to environmentaltobacco smoke: a comparison to concentrated ambient air fine particles exposu- re. Inhal Toxicol 2010;22:449-59. http://dx.doi.org/10.3109/08958370903373845 PMid:20235771 PMCid:3073493

Passive Smoking as a Risk Factor for Atherosclerotic Changes

Year 2012, Volume: 12 Issue: 1, 24 - 29, 01.01.2012
https://doi.org/10.5222/j.child.2012.024

Abstract

Objective: The aim of this study was to investigate the effect of passive smoking on carotid artery intimal medial thickness, blood lipid levels, lipoprotein levels and blood pressure. Methods: This descriptive study was carried out on 40 adolescents 20 girls and 20 boys aged 14-15 years who were identified as passive smokers at home and 40 adolescents 20 girls and 20 boys as the control group. Carotid artery intimal medial thickness, serum total cholesterol, LDL-C, HDL-C, VLDL-C, triglyceride levels and blood pressures were measured. Results: Carotid artery intimal medial thickness measurement, serum total cholesterol and LDL-C levels were significantly higher and serum HDL-C levels were significantly lower among passive smokers. Fasting blood glucose levels were normal in all cases. The mean systolic and diastolic blood pressure values of passive smokers group were significantly higher than those of control group. There was no difference in ejection fraction levels. Conclusion: Passive smoking may be an important risk factor for carotid atherosclerosis.

References

  • Lynch J, Krause N, Kaplan GA, Salonen R, Salonen J. Workplace demands, economic rewards and progression of carotid atherosclerosis. Circulation 1997;96:302-7. http://dx.doi.org/10.1161/01.CIR.96.1.302 PMid:9236449
  • Holman RL, Mc Gill HC, Strong JP, Geer JC. The natural history of atherosclerosis. Am J Pathol 1958;34:209-35. PMid:13520905 PMCid:1934740
  • Strong JP, Mc Gill HC Jr. The pediatric aspects of atherosc- lerosis. J Atheroscler Res 1969;9:251-65. http://dx.doi.org/10.1016/S0368-1319(69)80020-7
  • Bao W, Srinivasan RS, Valdez R, Greenlund JK, Wattlihney AW, Berenon SG. Longitudinal changes in cardiovascular risk from childhood to young adulthood in offspring of parents with coronary artery disease: The Bogalosa Heart Study. JAMA 1997;278:1749-54. http://dx.doi.org/10.1001/jama.1997.03550210047037
  • Bush PJ, Zuckerman AE, Theiss PK, Taggart VS, Horowitz C, Sheridon MJ. Walter HJ. Cardiovascular risk factor pre- vention in black schoolchildren: two year results of the “Know Your Body” program. Am J Epidemiol 1989;129:466-82. PMid:2916540
  • Bush PJ, Zuckerman AE, Taggart VS, Theiss PK, Peleg EO, Smith SA. Cardiovascular risk factor prevention in black school children: the “Know Your Body” evaluation project. Health Educ Q 1989;16:215-27. http://dx.doi.org/10.1177/109019818901600206
  • Fuster V, Badimon L, Bedimon JJ, Chesebro JH. The pat- honegesis of coronary artery disease and the acute coronary syndromes. N Engl J Med 1992;326:242-50. http://dx.doi.org/10.1056/NEJM199201233260406 PMid:1727977
  • Surgeon Generol. The Health Consequences of Smoking: CardiovascularDisease: A report of the surgeon General: Rockwille, Md US PublicHealth Service, Dept of Healthand Human Services, 1983.
  • Dwyer JH. Exposure to environmental tobacco smoke and coronary risk. Circulation 1997;96:1367-9. PMid:9315516
  • Garland C, Barrett-Connor E, Suarez L, Criqui MH, Wingard DL. Effects of passive smoking on ischemic heart disease mortality of non-smokers. A prospective study. Am J Epidemiol 1985;121:645-9. http://dx.doi.org/10.1093/aje/121.5.645 PMid:4014156
  • Gidding SS, Morgan W, Perry C, Jones JI, Bricker JT. Active and passive tobacco exposure: A serious pediatric health problem. A statement from the committee and atherosc- lerosis and hypertension in children, council on cardiovascular disease in the young, American Heart Association Circulation 1994;90:2581-90.
  • Hacettepe Halk Sağlığı Vakfı: Sigara içme konusundaki dav- ranışlar ve tutumlar Ankara / Türkiye: Özet rapor, 1997.
  • Crofton J. Tobacco: A future disaster for Turkey’s children. Turk J Pediatr 1996;38:1-11.
  • Hausberg M, Mark AL, Winniford MD, Brown RE, Somers VK. Sympathetic and vascular effects of short-term passive smoke exposure in healthy non-smokers. Circulation PMid:9236446
  • He Y, Lam TH, Li LS, Du RY, Jia GL, Huang JY, Zheng JS. Passive smoking at work as a risk factor for coronary heart disease in Chinese women who never smoked. BMJ 1994;308:380-4. http://dx.doi.org/10.1136/bmj.308.6925.380 PMid:8124145 PMCid:2539443
  • Howard G, Wagenknecht LE, Burke GL, Diez- Roux A, Evans GW, McGovern P, Nieto FJ, Tell GS. Cigarette smo- king and progression of atherosclerosis: The Atheroscleros is Risk In Commununities (ARIC) Study. JAMA 1998;279:119- 24. http://dx.doi.org/10.1001/jama.279.2.119
  • Moscıwitz WB, Mosteller M, Schieken RM, Bossano R, Hewitt JK, Bodurtha JN, Segrest JP. Lipoprotein and oxy- gen transport alteration in passive smoking preadolescent children. The MCV twin study. Circulation 1990;81:586-92. http://dx.doi.org/10.1161/01.CIR.81.2.586 PMid:2297864
  • Yamasaki Y, Kawamori R, Matsushima H, Nishizawa H, Kodama M, Kajimato Y, Morishima T, Kamada T. Atherosclerosis in carotidartery of young IDDM patients monitored by ultrasound high-resolution B-mode imaging. Diabetes 1994;43:634-9. http://dx.doi.org/10.2337/diabetes.43.5.634 PMid:8168638
  • National Council Research Council. Enviromental tobacco smoke measuring exposure and assesing health effects. Washington DC. National Academy Press 1996
  • Glantz SA, Parmley WW. Passive smoking and heart disea- se. Mechanisms and risk. JAMA 1995;273:1047-53. http://dx.doi.org/10.1001/jama.1995.03520370089043
  • Lightwood JM, Gliantz SA. Short-term economic and health benefits of smoking cessation: myocardial infarction and stro- ke. Circulation 1997;96:1089-96. http://dx.doi.org/10.1161/01.CIR.96.4.1089 PMid:9286934
  • Steenland K. Passive smoking and the risk of heart disease. JAMA 1992;267:94-9. http://dx.doi.org/10.1001/jama.1992.03480010102033
  • Chambless LE, Folsom AR, Davis V, Sharrett R, Heiss G, Sorlie P, Szklo M, Howard G, Evans GW. Risk factors for progression of common carotid atherosclerosis: the Atherosclerosis Risk in Communities Study, 1987-1998. Am J Epidemiol 2002;155:38-47. http://dx.doi.org/10.1093/aje/155.1.38 PMid:11772783
  • Homer D, Ingail TJ, Baker HL, O’Fallon WM, Kottke BA, Whisnant JP. Serum lipids and lipoproteins are less powerful predictors of extracranial carotid artery atherosclerosis than are cigarette smoking and hypertension. Mayo Clin Proc 1991;66:259-67. PMid:2002684
  • Celermajer DS, Adams MR, Clarkson P, Robinson J, McCredie R, Donald A, Deanfield JE. Passive smoking and impaired endothelium-dependent arterial dilatation in healthy young adults. N Engl J Med 1996;334:150-4. http://dx.doi.org/10.1056/NEJM199601183340303 PMid:8531969
  • Howard G, Burke GL, Szklo M, Tell GS, Eckfeldt J, Evans G, Heiss G. Active and passive smoking are associated with increased carotid wall thickness. The athe-rosclerosis risk in communities study. Arch Intern Med 1994;154:1277-82. http://dx.doi.org/10.1001/archinte.1994.00420110125014 PMid:8203995
  • Craig WY. Palomaki GE, Johnson AM, Haddow JE. Cigarette smoking associated changes in blood lipid and lipoprotein levels in the 8 to 19-year old group a meta- analysis. Pediatrics 1990;85:155-8. PMid:2136949
  • Feldman J, Shenker I, Etzel RA, Spierto FW, Lilienfield DE, Nussbaum M, Jacobson MS. Passive smoking alters lipid profiles in adolescents. Pediatrics 1991;88:259-64. PMid:1861923
  • Freedman DS, Srinivasan SR, Shear CL, Hunter SM, Craft JB, Webber LS, Berenson GS. Cigarette smoking initiaition and longitudinal changes in serum lipids and lipop- roteins in early adulthood. The Bogalosa Heart Study. Am J Epidemiol 1986;124:207-19. PMid:3728437
  • Diez- Roux AV, Nieto FJ, Comstock GW, Howard G, Szklom M. The relationship of active and passive smoking to carotid atherosclerosis 12-14 years later. Press Med 1995;24:48-55.
  • Nagel G, Arnold FJ, Wilhelm M, Link B, Zoellner I, Koenig W. Environmental tobacco smoke and cardiometabo- lic risk in young children: results from a survey in south-west Germany. Eur Heart J 2009;30:1885-93. http://dx.doi.org/10.1093/eurheartj/ehp180
  • Zielińska-Danch W, Wardas W, Sobczak A, Szołtysek- Bołdys I. Estimation of urinary cotinine cut-off points distin- guishing non-smokers, passiveand active smokers. Biomarkers http://dx.doi.org/10.1080/13547500701421341 PMid:17701747
  • Chen LC, Quan C, Hwang JS, Jin X, Li Q, Zhong M, Rajagopalan S, Sun Q. Atherosclerosis lesion progression during inhalation exposure to environmentaltobacco smoke: a comparison to concentrated ambient air fine particles exposu- re. Inhal Toxicol 2010;22:449-59. http://dx.doi.org/10.3109/08958370903373845 PMid:20235771 PMCid:3073493
There are 33 citations in total.

Details

Primary Language Turkish
Journal Section Research Articles
Authors

Ayşe Kılıç This is me

İsmail Yıldız This is me

Rukiye Eker Ömeroğlu This is me

Emin Ünüvar This is me

Talat Cantez This is me

Publication Date January 1, 2012
Published in Issue Year 2012 Volume: 12 Issue: 1

Cite

APA Kılıç, A., Yıldız, İ., Eker Ömeroğlu, R., Ünüvar, E., et al. (2012). Pasif Sigara İçiciliğinin Çocuklarda Aterosklerotik Risk Faktörlerine Etkisi. Çocuk Dergisi, 12(1), 24-29. https://doi.org/10.5222/j.child.2012.024
AMA Kılıç A, Yıldız İ, Eker Ömeroğlu R, Ünüvar E, Cantez T. Pasif Sigara İçiciliğinin Çocuklarda Aterosklerotik Risk Faktörlerine Etkisi. Çocuk Dergisi. January 2012;12(1):24-29. doi:10.5222/j.child.2012.024
Chicago Kılıç, Ayşe, İsmail Yıldız, Rukiye Eker Ömeroğlu, Emin Ünüvar, and Talat Cantez. “Pasif Sigara İçiciliğinin Çocuklarda Aterosklerotik Risk Faktörlerine Etkisi”. Çocuk Dergisi 12, no. 1 (January 2012): 24-29. https://doi.org/10.5222/j.child.2012.024.
EndNote Kılıç A, Yıldız İ, Eker Ömeroğlu R, Ünüvar E, Cantez T (January 1, 2012) Pasif Sigara İçiciliğinin Çocuklarda Aterosklerotik Risk Faktörlerine Etkisi. Çocuk Dergisi 12 1 24–29.
IEEE A. Kılıç, İ. Yıldız, R. Eker Ömeroğlu, E. Ünüvar, and T. Cantez, “Pasif Sigara İçiciliğinin Çocuklarda Aterosklerotik Risk Faktörlerine Etkisi”, Çocuk Dergisi, vol. 12, no. 1, pp. 24–29, 2012, doi: 10.5222/j.child.2012.024.
ISNAD Kılıç, Ayşe et al. “Pasif Sigara İçiciliğinin Çocuklarda Aterosklerotik Risk Faktörlerine Etkisi”. Çocuk Dergisi 12/1 (January 2012), 24-29. https://doi.org/10.5222/j.child.2012.024.
JAMA Kılıç A, Yıldız İ, Eker Ömeroğlu R, Ünüvar E, Cantez T. Pasif Sigara İçiciliğinin Çocuklarda Aterosklerotik Risk Faktörlerine Etkisi. Çocuk Dergisi. 2012;12:24–29.
MLA Kılıç, Ayşe et al. “Pasif Sigara İçiciliğinin Çocuklarda Aterosklerotik Risk Faktörlerine Etkisi”. Çocuk Dergisi, vol. 12, no. 1, 2012, pp. 24-29, doi:10.5222/j.child.2012.024.
Vancouver Kılıç A, Yıldız İ, Eker Ömeroğlu R, Ünüvar E, Cantez T. Pasif Sigara İçiciliğinin Çocuklarda Aterosklerotik Risk Faktörlerine Etkisi. Çocuk Dergisi. 2012;12(1):24-9.