Trombositopeni ve Çoklu Organ Yetersizliği: İkisi Arasında Bağlantı Var mı?

Year 2009, Volume: 9 Issue: 1, 52 - 56, 01.01.2009

Demet Demirkol Ahmet Nayır Metin Karaböcüoğlu Ayşegül Ünüvar Ömer Devecioğlu Diana Yanni

Abstract

Çoklu organ yetersizliği, kritik hastalarda görülen en ciddi komplikasyonlardandır. Çoklu organ yetersizliği ile yaygın sistemik tromboz arasında ilişki olduğu gösterilmiştir. Bu ilişkiye dayanarak son yıllarda trombositopeni ilişkili çoklu organ yetersizliği kavramı kullanılmaya başlamıştır. Trombositopeni ilişkili çoklu organ yetersizliği trombotik trombositopenik purpura, ikincil trombotik mikroanjiyopa- ti ve dissemine intravasküler koagülasyonu kapsayan patoloji spektrumlarıdır. Bu makalemizde trombositopeni ile başvuran ve çoklu organ yetersizliği gelişen bir vaka sunulmaktadır

Keywords

Çoklu organ yetersizliği, trombositopeni, trombositopeni ilişkili çoklu organ yetersizliği, trombotik trombositopenik purpura, trombotik mikroanjiyopati, dissemine intravasküler koagulasyon

Thrombocytopenia and Multiple Organ Failure: Is There an Association?

Abstract

Multiple organ failure is one of the most severe complica- tions of the critically ill patients. The contributing role of the systemic thrombosis and related organ dysfunction is clearly demonstrated. According to this relationship thrombocytopenia-associated multiple organ failure is a recently defined syndrome. Thrombocytopenia-associated multiple organ failure is a thrombotic microangiopathic syndrome that can be defined by a spectrum of pathologies that includes thrombotic thrombocytopenic purpura, secon- dary thrombotic microangiopathy, and disseminated intra- vascular coagulation. In this paper we described a patient who has a thrombocytopenia and multiple organ failure

Keywords

Multiple organ failure, thrombocytopenia, thrombocytopenia-associated multiple organ failure, thrombotic thrombocytopenic purpura, thrombotic microangiopathy, disseminated intravascular coagulation

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