Indroduction: In adolescence, personal care routines pass from parental control to the children. During this period, children develop independence in personal hygiene, clothing preferences, nutritional habits, and adhering to medical treatments. In case of lack of parental support and monitoring, it takes time for personal care habits to settle.Case: 16-year-old female patient was diagnosed with deep neck infection and descendant mediastinitis with massive pleural effusion. The patient discontinued her prior dental abscess treatment due to progressive dysphagia. The patient underwent surgery for neck exploration, insertion of a cervical drain, tracheostomy, and chest tube. Although tests for immunodeficiency were screened, no significant result was found. The patient was discharged on the 33rd day. Conclusion: In adolescence, challenges arise in maintaining effective clinical relationships, especially regarding risk-taking behaviors and adherence to medical treatment in the face of illness. Parental support and healthcare providers play a vital role in facilitating this transition by educating adolescents on self-care practices and increasing parental monitoring during this developmental phase. Also developing algorithms that address biopsychosocial integrity through artificial intelligence will contribute to identifying patients who are likely to be non-compliant with treatment.