Journal of Emergency Medicine Case Reports

2149-9934

Acil Tıp Uzmanları Derneği

10.33706/jemcr.550556

USE OF HIGH-DOSE OF UROKINASE DURING CARDIOPULMONARY RESUSCITATION FOR CLINICALLY SUSPECTED MASSIVE PULMONARY EMBOLISM.

Chiscano Camon

Luis

Ruiz Rodriguez

Juan Carlos

Anselmo

Laura Dono

Sanmartin

Adolf Ruiz

01 01 2019

10 1 17 20 05 11 2018 09 15 2018

2010

Journal of Emergency Medicine Case Reports

Introduction: We are presenting6 patients who suffered a cardiac arrest (CA) for suspected pulmonary embolism.Before establishing a definitive diagnosis, advanced life support (ALS)algorithm was initiated. Urokinase dosed as 15.000 UI/kg (weight) wasadministered initially, followed by 4.400 UI/Kg for 12 hours as a continuousintravenous perfusion. Two patients presented absolute contraindications for fibrinolytictherapy, however only one patient presented a major hemorrhagic complication.Global mortality rate was 83%. Case report: We present 6 casesof patients with CA due to MPEwho were treated with high doses of urokinase during cardiopulmonary resuscitationand later admitted to the Intensive Care Unit (ICU).Conclusion: Our observations suggest that the clinical suspected MPE with CA can also beone of the recommended applications of thrombolysis with high-dose bolusinjection of thrombolytic with efficacy.

cardiac arrest cardiopulmonary resuscitation pulmonary embolism reperfusion

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