Özkıyım Amaçlı İntramuskuler Organofosfat Enjeksiyonu Sonrası İntermediate Sendrom Gelişimi: Olgu Sunumu

Year 2010, Volume: 1 Issue: 2, 44 - 47, 01.04.2010

Hızır Ufuk Akdemir , Türker Yardan Ahmet Baydın Ethem Acar Bora Arslan

Abstract

Organophosphate (OP) poisonings can cause serious clinical outcome. These
poisonings generally occur after oral, inhalation or skin exposures of OP.
However, OP poisoning occurred after parenteral administration is rare. The
injection of OP to the body can cause different clinical results such as local
complications and systemic toxicity. In some cases with acute OP poisoning,
the intermediate syndrome may develop which can life threatens as a result
of respiratory muscle weakness after 1-4 days of exposure. In this study, we
reported a case admitted to the Emergency Department after intramuscular
injection of OP to himself and developed intermediate syndrome during the
observation, and we also discussed the required clinical precautions after
OP injection

Keywords

Organophosphate poisoning, intramuscular injection, intermediate syndrome

A Case Report: Intermediate Syndrome After Intramuscular Injection of Organophosphate Including Insectısıdes for Suicidal Attempt

Abstract

Organophosphate (OP) poisonings can cause serious clinical outcome. These poisonings generally occur after oral, inhalation or skin exposures of OP. However, OP poisoning occurred after parenteral administration is rare. The injection of OP to the body can cause different clinical results such as local complications and systemic toxicity. In some cases with acute OP poisoning, the intermediate syndrome may develop which can life threatens as a result of respiratory muscle weakness after 1-4 days of exposure. In this study, we reported a case admitted to the Emergency Department after intramuscular injection of OP to himself and developed intermediate syndrome during the observation, and we also discussed the required clinical precautions after OP injection

Keywords

Organophosphate poisoning, intramuscular injection, intermediate syndrome

References

• Tunçok Y, Hocaoğlu Aksay N. Organofosfatlı insektisitlerle zehirlenme. Türkiye Klinikleri Cerrahi Tıp Bilimleri Acil Tıp Dergisi 2006;2:69-73.
• Al B, Güllü MN, Küçüköner M, Aldemir M, Güloğlu C. Dicle Üniversitesi Tıp Fakültesi acil servisine organofosfat zehirlenmeleri ile başvuran hastaların demografik özellikleri. Tıp Araştırmaları Dergisi 2006;4:5-13.
• Berger AR, Schaumburg HH. Effect of occupational and environmental agents on the nervous system. In Bradley WG, Editor. Neurology in Clinical Practice. Boston: Butterworth-Heinemann; 1996:. p.1389-401.
• Sabancı Ü, Aydın İ. Özkıyım amaçlı intramuskuler Dichlorvos enjeksiyonu: Olgu sunumu. Genel Tıp Dergisi 2008;18:169-71.
• Robey WC, Meggs WJ. Insecticides, Herbicides and Rodenticides. In Judith E. Tintinally, Editor Emergency Medicine. 6 th ed. New York: McGraw-Hill; 2004: p.333- 343.
• Sarıtaş A, Çakır Z, Aslan Ş. Organofosfat ve karbamat zehirlenmeleri. EAJM 2007;39:55-9.
• Eyer P. The role of oximes in the management of organophosphorus pesticide poisoning. Toxicol Rev. 2003;22:165-90.
• Eddleston M, SziniczL, Eyer P, Buckley N. Oximes in acute organophosphorous pesticide poisoning: a systematic review of clinical trials. Q J Med. 2002;95:275- 83.
• Güloğlu C, Eriş S, Sayhan MB. Intramuscular injection of diazinon aimed suicide. Turkish J Toxicol. 2006;4:11- 4.
• Hadimioglu N, Dosemeci L, Arici G, Ramazanoglu A. Systemic organophosphate poisoning following the percutaneous injection of insecticide. Case report. Skin Pharmacol Appl Skin Physiol. 2002;15:195-9.
• Guloglu C, Aldemir M, Orak M, Kara IH. Dichlorvos poisoning after intramuscular injection. Am J Emerg Med. 2004;22:328-30.