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Akut Brusellozis ile İlişkili Akut Derin Ven Trombozu: Olgu sunumu

Year 2012, Volume: 3 Issue: 4, 118 - 120, 01.10.2012

Abstract

Brusellozis, dünya çapında en yaygın zoonozlardan biri olmayı
sürdürmektedir. İnsan brusellozu bir çoklu sistem hastalığıdır ve
çok çeşitli klinik bulgularla karşımıza gelebilir. Bazen enfeksiyon
serolojik olarak pozitif olmasına rağmen asemptomatik olabilir.
Burada 26 yaşında mezbaha işçisi bir erkek hastada, brusellozisi
takiben gelişen derin ven trombozu (DVT) olgusu sunuldu. Hasta bir haftadır devam eden halsizlik, ateş ve sağ bacağında ağrı
ve şişlik şikayeti ile başvurdu. Renkli doppler ultrasonografisinde
sağ femoral ve popliteal venlerin trombüsle tıkalı olduğu görüldü. Brusella tanısı Rose-Bengal, tüp aglütinasyon, brucellacapt
and enzim immunoassay anti-brucella abortus Ig M, G testleri
ile, başka bir kurumda konmuştu. Nadiren de olsa bazı enfeksiyöz ajanların vasküler patolojilere neden olabildiği bildirilmiştir.
Bunlar bazan hayatı tehdit edici olabilmektedir. Bu enfeksiyonların seyri esnasında vasküler komplikasyonlar gelişebileceği akılda
tutulmalıdır ve hasta yakından izlenmelidir. Yine DVT ve benzeri
patolojilerle başvuranlarda, diğer risk faktörleri yanında brusella
ve salmonella gibi enfeksiyon ajanları da araştırılmalıdır.

References

  • Odeh M, Pick N, Oliven A. Deep venous thrombosis associated with acute brucellosis: A case report. Angiology 2000; 51: 253-6. [CrossRef]
  • Young EJ. Human brucellosis. Rev Infect Dis 1983; 5: 821-42. [CrossRef]
  • Colmenero JD, Reguera JM, Martos F, Sanchez-de-Mora D, Delgado M, Causse M, et al. Complications associated with brucella melitensis in- fection: A study of 530 cases. Medicine 1996; 75: 195-211. [CrossRef]
  • Marfil-Rivera LJ, Mares Ramirez MA, Mora-Brondo P, et al. Deep venous thrombosis in a patient with brucellosis and probable lupoid inhibitor. Rev Invest Clin 1986; 38: 311-5.
  • Ocon P, Reguera JM, Morata P, Juarez C, Alonso A, Colmenero JD. Pha- gocytic cell function in active brucellosis. Infect Immun 1994; 62: 910-4.
  • Spink WW. Some biological and clinical problems related to intracellu- lar parasitism in brucellosis. N Eng J Med 1952; 247: 603-10. [CrossRef]
  • Gerghiou PR, Young EJ. Prolonged incubation in brucellosis. Lancet 1991; 337: 1543. [CrossRef]
  • Sanchez-Gonzales J, Garcia-Delange T, Martos F, Colmenero JD. Throm- bosis of the abdominal aorta secondary to Brucella spondylitis. Infecti- on 1996; 24: 261-2. [CrossRef]
  • Gelfand MS, Kaiser AB, Dale WA. Localized brucellosis: popliteal artery aneurysm, mediastinitis, dementia and pneumonia. Rev Infect Dis 1989; 11: 783-8. [CrossRef]
  • Gregori J, Ortuño J, Ruiz Rivas JL, Arenas M. Brucellosis and portal thrombosis. Rev Esp Enferm Dig 1990; 78: 187-8.
  • Zaidan R, Al Tahan AR. Cerebral venous thrombosis: A new manifestati- on of neurobrucellosis. Clin Infect Dis 1999; 28: 399-400. [CrossRef]
  • Ceyhan M, Kanra G, Benderlioglu B, Secmeer G, Hicsonmez G, Kirazli S. Transient protein S deficiency with deep venous thrombosis during Sal- monella typhimurium infection. Arch Dis Child 1993; 68: 138-9. [CrossRef]
  • Gogos CA, Apostolidou E, Bassaris HP, Vagenakis AG. Three cases of vari- cella thrombophlebitis as a complication of varicella zoster virus infec- tion. Eur J Clin Microbiol Infect Dis 1993; 12: 43-5. [CrossRef]
  • Becker DM, Saunders TJ, Wispelwey B, Schain DC. Case report: venous thromboembolism in AIDS. Am J Med 1992; 303: 395-7. [CrossRef]

Acute Deep Venous Thrombosis Associated with Acute Brucellosis: A Case Report

Year 2012, Volume: 3 Issue: 4, 118 - 120, 01.10.2012

Abstract

Brucellosis continues to be one of the most widespread zoonoses worldwide. Human brucellosis is a multisystem disease that may present with a broad spectrum of clinical manifestations, but it may also be asymptomatic with only serological evidence of infection. In this paper, a case report is presented of deep venous thrombosis (DVT) developing after a diagnosis of acute brucellosis in a young slaughterhouse worker. A 26-year-old man was diagnosed with DVT which had presented with the complaints of weakness and fever and a one-week history of pain and swelling in the right leg. Ultrasound revealed that the right femoral and popliteal veins were occluded with thrombi. Brucella was diagnosed using Rose-Bengal, tube agglutination, the Brucellacapt test and an enzyme-linked immunoassay using anti-Brucella abortus IgM/G antibody detection at another institution. Although rare, some infectious agents may cause vascular pathologies. These conditions may be life-threatening. Thus, it should be kept in mind that vascular complications may occur during infectious disease and patients should be monitored. Additionally, patients presenting with symptoms of DVT or similar vascular pathologies should be assessed for infectious agents, particularly Brucella and Salmonella, as well as other risk factors

References

  • Odeh M, Pick N, Oliven A. Deep venous thrombosis associated with acute brucellosis: A case report. Angiology 2000; 51: 253-6. [CrossRef]
  • Young EJ. Human brucellosis. Rev Infect Dis 1983; 5: 821-42. [CrossRef]
  • Colmenero JD, Reguera JM, Martos F, Sanchez-de-Mora D, Delgado M, Causse M, et al. Complications associated with brucella melitensis in- fection: A study of 530 cases. Medicine 1996; 75: 195-211. [CrossRef]
  • Marfil-Rivera LJ, Mares Ramirez MA, Mora-Brondo P, et al. Deep venous thrombosis in a patient with brucellosis and probable lupoid inhibitor. Rev Invest Clin 1986; 38: 311-5.
  • Ocon P, Reguera JM, Morata P, Juarez C, Alonso A, Colmenero JD. Pha- gocytic cell function in active brucellosis. Infect Immun 1994; 62: 910-4.
  • Spink WW. Some biological and clinical problems related to intracellu- lar parasitism in brucellosis. N Eng J Med 1952; 247: 603-10. [CrossRef]
  • Gerghiou PR, Young EJ. Prolonged incubation in brucellosis. Lancet 1991; 337: 1543. [CrossRef]
  • Sanchez-Gonzales J, Garcia-Delange T, Martos F, Colmenero JD. Throm- bosis of the abdominal aorta secondary to Brucella spondylitis. Infecti- on 1996; 24: 261-2. [CrossRef]
  • Gelfand MS, Kaiser AB, Dale WA. Localized brucellosis: popliteal artery aneurysm, mediastinitis, dementia and pneumonia. Rev Infect Dis 1989; 11: 783-8. [CrossRef]
  • Gregori J, Ortuño J, Ruiz Rivas JL, Arenas M. Brucellosis and portal thrombosis. Rev Esp Enferm Dig 1990; 78: 187-8.
  • Zaidan R, Al Tahan AR. Cerebral venous thrombosis: A new manifestati- on of neurobrucellosis. Clin Infect Dis 1999; 28: 399-400. [CrossRef]
  • Ceyhan M, Kanra G, Benderlioglu B, Secmeer G, Hicsonmez G, Kirazli S. Transient protein S deficiency with deep venous thrombosis during Sal- monella typhimurium infection. Arch Dis Child 1993; 68: 138-9. [CrossRef]
  • Gogos CA, Apostolidou E, Bassaris HP, Vagenakis AG. Three cases of vari- cella thrombophlebitis as a complication of varicella zoster virus infec- tion. Eur J Clin Microbiol Infect Dis 1993; 12: 43-5. [CrossRef]
  • Becker DM, Saunders TJ, Wispelwey B, Schain DC. Case report: venous thromboembolism in AIDS. Am J Med 1992; 303: 395-7. [CrossRef]
There are 14 citations in total.

Details

Other ID JA36BK88MS
Journal Section Case Report
Authors

Sedat Koçak This is me

Cesarettin Dikmetaş This is me

Zerrin Defne Dündar This is me

Esra Erdemir This is me

Recep Keşli This is me

Publication Date October 1, 2012
Submission Date October 1, 2012
Published in Issue Year 2012 Volume: 3 Issue: 4

Cite

APA Koçak, S., Dikmetaş, C., Dündar, Z. D., Erdemir, E., et al. (2012). Acute Deep Venous Thrombosis Associated with Acute Brucellosis: A Case Report. Journal of Emergency Medicine Case Reports, 3(4), 118-120.
AMA Koçak S, Dikmetaş C, Dündar ZD, Erdemir E, Keşli R. Acute Deep Venous Thrombosis Associated with Acute Brucellosis: A Case Report. Journal of Emergency Medicine Case Reports. October 2012;3(4):118-120.
Chicago Koçak, Sedat, Cesarettin Dikmetaş, Zerrin Defne Dündar, Esra Erdemir, and Recep Keşli. “Acute Deep Venous Thrombosis Associated With Acute Brucellosis: A Case Report”. Journal of Emergency Medicine Case Reports 3, no. 4 (October 2012): 118-20.
EndNote Koçak S, Dikmetaş C, Dündar ZD, Erdemir E, Keşli R (October 1, 2012) Acute Deep Venous Thrombosis Associated with Acute Brucellosis: A Case Report. Journal of Emergency Medicine Case Reports 3 4 118–120.
IEEE S. Koçak, C. Dikmetaş, Z. D. Dündar, E. Erdemir, and R. Keşli, “Acute Deep Venous Thrombosis Associated with Acute Brucellosis: A Case Report”, Journal of Emergency Medicine Case Reports, vol. 3, no. 4, pp. 118–120, 2012.
ISNAD Koçak, Sedat et al. “Acute Deep Venous Thrombosis Associated With Acute Brucellosis: A Case Report”. Journal of Emergency Medicine Case Reports 3/4 (October 2012), 118-120.
JAMA Koçak S, Dikmetaş C, Dündar ZD, Erdemir E, Keşli R. Acute Deep Venous Thrombosis Associated with Acute Brucellosis: A Case Report. Journal of Emergency Medicine Case Reports. 2012;3:118–120.
MLA Koçak, Sedat et al. “Acute Deep Venous Thrombosis Associated With Acute Brucellosis: A Case Report”. Journal of Emergency Medicine Case Reports, vol. 3, no. 4, 2012, pp. 118-20.
Vancouver Koçak S, Dikmetaş C, Dündar ZD, Erdemir E, Keşli R. Acute Deep Venous Thrombosis Associated with Acute Brucellosis: A Case Report. Journal of Emergency Medicine Case Reports. 2012;3(4):118-20.