Abstract
Civan perçemi (Achillea millefolium), halk arasında anti-inflamatuar, anti-ülser ve östrojen benzeri etkisi nedeniyle yaygın kullanılan
bir bitkidir. Bu bitkisel tedaviyle ilgili olarak, içinde dermal alerjik
reaksiyonların da bulunduğu bazı yan etkiler bildirilmiştir. Fakat
achillea türleriyle ilgili literatürde antikolinerjik toksisiteye rastlanmamaktadır. Kırk üç yaşındaki kadın hasta acil servise görme
bozukluğu, ağızda kuruluk, yüzde kızarma ve çarpıntı şikayetleriyle başvurdu. Bilinen sistemik bir hastalığı yoktu ve civan perçemi
çayı (bir haftadan beri günde beş bardak) dışında kullandığı bitkisel bir ilaç veya tedavi bulunmamaktaydı. Bitkisel çayı, menometroraji şikayeti için kullandığını belirtmekteydi. Yapılmış çalışmalara
göre achillea türlerindeki içerik oldukça biyoaktif olmakla birlikte,
bitkinin tüm etkileri iyi bilinmemektedir. Achillea türlerinin tedavi
amaçlı kullanımı güvenli kabul edilmiş olsa da, farklı farmakolojik
etkileri dikkatle ele alınmalıdır.
Keywords
References
- Khan AU, Gilani AH. Blood pressure lowering, cardiovascular inhibitory and bronchodilatory actions of Achillea millefolium. Phytother Res 2011; 25: 577-83. [CrossRef]
- de Souza P, Gasparotto A Jr, Crestani S, Stefanello MÉ, Marques MC, da Sil- va-Santos JE, et al. Hypotensive mechanism of the extracts and artemetin isolated from Achillea millefolium L. (Asteraceae) in rats. Phytomedicine 2011; 18: 819-25. [CrossRef]
- Benedek B, Kopp B. Achillea millefolium L. s.l. revisited: recent findings confirm the traditional use. Wien Med Wochenschr 2007; 157: 312-4. [CrossRef]
- Radulović NS, Dekić MS, Ranđelović PJ, Stojanović NM, Zarubica AR, Stojanović-Radić ZZ. Toxic essential oils: Anxiolytic, antinociceptive and antimicrobial properties of the yarrow Achillea umbellata Sibth. et Sm. (Asteraceae) volatiles. Food Chem Toxicol 2012; 50: 2016-26. [CrossRef]
- Applequist WL, Moerman DE. Yarrow (Achillea millefolium L.): A ne- glected panacea? A review of ethnobotany, bioactivity, and biomedical research. Economic Botany 2011; 65: 209-25. [CrossRef]
- Moerman DE. Agreement and meaning: rethinking consensus analysis. J Ethnopharmacol 2007; 112: 451-60. [CrossRef]
- Si XT, Zhang ML, Shi QW, Kiyota H. Chemical constituents of the plants in the genus Achillea. Chem Biodivers 2006; 3: 1163-80. [CrossRef]
- Karamenderes C, Apaydin S. Antispasmodic effect of Achillea nobilis L. subsp. sipylea (O. Schwarz) Bässler on the rat isolated duodenum. J Eth- nopharmacol 2003; 84: 175-9. [CrossRef]
- Bildik F, Kahveci O, Aygencel G, Keleş A, Demircan A, Aksel G, et al. Two herbal poisoning cases from Turkey; Datura for haemorrhoidal pain relief, Mandragora for aphrodisiac effect. AKATOS 2011; 2: 18-21.
- Özkan S, Salt Ö, İpekçi A, Düzgün A, İkizceli İ. Poisoning due to Datura inoxia tea. AKATOS 2010; 2: 11-3.
Abstract
Yarrow (Achillea millefolium) is a widely used plant in folk medicine due to its anti-inflammatory, anti-ulcer and estrogen-related effects. Some side effects including dermal allergic reactions have been reported owing to this herbal remedy. However, the literature about Achillea species do not include any side effects indicating anticholinergic toxicity. A 43-year-old female patient presented to the emergency department with blurred vision, dryness in the mouth, facial flushing and palpitation. She did not have any systemic illnesses and she denied taking any other herbal drugs or medications except yarrow tea (five cups a day, for one week), which she used for the treatment of menometrorrhagia. The constituents of the Achillea species identified in the former studies are highly bioactive, but their effects are not entirely known. Although the Achillea species have been considered as safe medicinal plants, the various pharmacological effects of Achillea species should be cautiously handled
References
- Khan AU, Gilani AH. Blood pressure lowering, cardiovascular inhibitory and bronchodilatory actions of Achillea millefolium. Phytother Res 2011; 25: 577-83. [CrossRef]
- de Souza P, Gasparotto A Jr, Crestani S, Stefanello MÉ, Marques MC, da Sil- va-Santos JE, et al. Hypotensive mechanism of the extracts and artemetin isolated from Achillea millefolium L. (Asteraceae) in rats. Phytomedicine 2011; 18: 819-25. [CrossRef]
- Benedek B, Kopp B. Achillea millefolium L. s.l. revisited: recent findings confirm the traditional use. Wien Med Wochenschr 2007; 157: 312-4. [CrossRef]
- Radulović NS, Dekić MS, Ranđelović PJ, Stojanović NM, Zarubica AR, Stojanović-Radić ZZ. Toxic essential oils: Anxiolytic, antinociceptive and antimicrobial properties of the yarrow Achillea umbellata Sibth. et Sm. (Asteraceae) volatiles. Food Chem Toxicol 2012; 50: 2016-26. [CrossRef]
- Applequist WL, Moerman DE. Yarrow (Achillea millefolium L.): A ne- glected panacea? A review of ethnobotany, bioactivity, and biomedical research. Economic Botany 2011; 65: 209-25. [CrossRef]
- Moerman DE. Agreement and meaning: rethinking consensus analysis. J Ethnopharmacol 2007; 112: 451-60. [CrossRef]
- Si XT, Zhang ML, Shi QW, Kiyota H. Chemical constituents of the plants in the genus Achillea. Chem Biodivers 2006; 3: 1163-80. [CrossRef]
- Karamenderes C, Apaydin S. Antispasmodic effect of Achillea nobilis L. subsp. sipylea (O. Schwarz) Bässler on the rat isolated duodenum. J Eth- nopharmacol 2003; 84: 175-9. [CrossRef]
- Bildik F, Kahveci O, Aygencel G, Keleş A, Demircan A, Aksel G, et al. Two herbal poisoning cases from Turkey; Datura for haemorrhoidal pain relief, Mandragora for aphrodisiac effect. AKATOS 2011; 2: 18-21.
- Özkan S, Salt Ö, İpekçi A, Düzgün A, İkizceli İ. Poisoning due to Datura inoxia tea. AKATOS 2010; 2: 11-3.
Details
| Other ID | JA89HG75JD |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | July 1, 2013 |
| Submission Date | July 1, 2013 |
| Published in Issue | Year 2013 Volume: 4 Issue: 3 |