j. fac. pharm. ankara

Journal of Faculty of Pharmacy of Ankara University

1015-3918 2564-6524

Ankara University

10.33483/jfpau.840362

Pharmacology and Pharmaceutical Sciences

Eczacılık ve İlaç Bilimleri

ANTEP FISTIĞI (PISTACIA VERA L.) MEYVE KABUĞU: BİYOAKTİF BİLEŞİKLER İÇİN POTANSİYEL KAYNAK

PISTACHIO (PISTACIA VERA L.) FRUIT HULL: POTENTIAL SOURCE FOR BIOACTIVE COMPOUNDS

https://orcid.org/0000-0002-9241-2496

Hürkul

Muhammed Mesud

ANKARA ÜNİVERSİTESİ, ECZACILIK FAKÜLTESİ

09 27 2021

45 3 586 597 12 14 2020 04 06 2021

1971

Journal of Faculty of Pharmacy of Ankara University

Amaç: Bu derleme çalışması, ekonomik öneme sahip olan Antep fıstığı (Pistacia vera L.) meyvesinin ticari bakımdan değersiz bir atık ürünü olan meyve kabuklarının eczacılık açısından değerlendirilmesi ve ekonomiye katkı sağlayacak şekilde farklı ürünlere dönüştürülebilme potansiyeli araştırılmıştır. Bu amaçla, şimdiye kadar yapılan fitokimyasal ve biyolojik aktivite çalışmaları derlenmiştir.Sonuç ve Tartışma: Yapılan fitokimyasal çalışmalar bitkinin meyve kabuklarının gallik asit ve türevleri, flavonoitler ve anakardik asitler içerdiğini göstemiştir. Ayrıca yapılan biyoaktivite çalışmaları Antep fıstığı meyve kabuklarının antioksidan, antimikrobiyal, antienflamatuvar, anti-tirozinaz, anti-kanser ve yara iyi edici aktivitelerinin olduğunu göstermiştir. Bu derleme çalışması tarımsal gıda atığı olan Antep fıstığı meyve kabuklarından elde edilecek biyoaktif moleküllerin eczacılık alanında değerlendirilebilme potansiyelinin olduğunu göstermiştir.

Objective: In this review, the evaluation of the pistachio (Pistacia vera L.) fruit hull, which is an economically worthless by-product, in terms of pharmacy and the potential to be transformed into different products to contribute to the economy was investigated. For this purpose, the results of phytochemical and biological activity studies were evaluated.Result and Discussion: Phytochemical studies have shown that the fruit hull of the plant contain gallic acid and its derivatives, flavonoids and anacardic acids. In addition, bioactivity studies have shown that pistachio fruit hulls have antioxidant, antimicrobial, anti-inflammatory, anti-tyrosinase, anti-cancer and wound healing activities. This review study has shown that bioactive molecules obtained from pistachio fruit hulls, which are agricultural food waste, have the potential to be utilized in the field of pharmacy.

Biyolojik aktivite derleme kimyasal içerik meyve kabuğu Pistacia vera yan ürün

Biological activity review chemical content fruit hull Pistacia vera by-product

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