SOLUNUM YOLU HASTALIKLARINDA TIBBİ BİTKİ KULLANIMI ÜZERİNE ANKET TABANLI BİR ÇALIŞMA

Abstract

Amaç: Bu çalışmada, solunum yolu hastalıklarında tıbbi bitki kullanım oranının, bitki türlerinin, ayrıntılı kullanım ve satın alma bilgilerinin, bitki kullanma eğilimini etkileyen sosyodemografik özelliklerin ve sağlık profesyonellerine bildirim durumlarının araştırılması amaçlanmıştır.
Gereç ve Yöntem: Araştırma 2018 yılı Ocak-Nisan ayları arasında Molla Gürani Aile Sağlığı Merkezi'nde gerçekleştirildi. Solunum yolu hastalarına 18 maddelik bir anket formu uygulandı. Elde edilen verilerin analizleri SPSS sürüm 26.0 yazılımında Ki-kare ve Fisher's Exact testi kullanılarak yapıldı.
Sonuç ve Tartışma: Ankete katılan 62 solunum yolu hastasının 64.5%'inin tıbbi bitkileri kullandığı belirlenmiştir. Toplamda 14 farklı bitki ve bitki karışımının kullanıldığı, bunlardan en yaygın olarak nane-limon, meyan kökü, ıhlamur ve kuşburnu tercih edildiği görülmüştür. Bitki kullanan ve kullanmayan gruplar arasında cinsiyet (p=0.01) ve yerleşim (p=0.007) istatistiksel olarak anlamlıdır. Hastaların bitkilerden yararlanma ve bitki tavsiye etme oranlarının da yüksek olduğu görülmüştür (sırasıyla 87.5%, 90%). Kullanıcıların sadece %40'ı doktorlarına bitki kullanımını bildirirken, yaş (p=0,029), eğitim durumu (p=0,002) ve yerleşim yerinin (p=0,015) istatistiksel olarak anlamlı olduğu bulunmuştur. Çalışma, solunum yolu hastalıklarında yaygın olarak kullanılan tıbbi bitkiler üzerinde daha fazla araştırma yapılması gerektiğini göstermiştir.

Keywords

• Geleneksel ve tamamlayıcı tıp
• solunum yolu hastalıkları
• tıbbi bitkiler

A QUESTIONNAIRE-BASED STUDY ON MEDICINAL PLANT USE IN RESPIRATORY DISEASES

Abstract

Objective: We aimed to investigate the rates of medicinal plant use, species of medicinal plants, detailed usage and procurement information, the sociodemographic features affecting the tendency to use plants and the notification status to healthcare professionals in patients with respiratory diseases.

Material and Method: This study was carried out between January-April 2018 at the Molla Gurani Family Healthcare Center. An 18-item survey questionnaire was administered to patients suffered from respiratory diseases. Analysis were made in SPSS version 26.0 software using both chi-square analysis and Fisher's Exact test.

Result and Discussion: Of the 62 patients, 64.5% had used medicinal plants to treat respiratory diseases. A total of 14 different plants and plant mixture were determined, most commonly used were mint-lemon, licorice, linden and rosehip. Gender (p=0.01) and inhabitation (p=0.007) were significant between the groups that used and did not use plants. The rates of patients' benefiting from plants and recommending plants were also found to be high (87.5%, 90%, respectively). Only 40% of users had notified their doctor, age (p=0.029), educational status (p=0.002) and inhabitation (p=0.015) were statistically significant for notification to healthcare professionals about plant usage. This study has demonstrated the need for further research into commonly used medicinal plants in respiratory diseases.

Keywords

• Complementary alternative medicine
• medicinal plants
• respiratory diseases

References

1. 1. Forum of International Respiratory Societies. (2017). The Global Impact of Respiratory Disease, 2nd ed, European Respiratory Society, Sheffield.
2. 2. Jardins, T.D., Burton, G. (2020). Clinical Manifestations and Assessment of Respiratory Disease, 8th ed, Mosby, London.
3. 3. Brennan, N.J. (2017). Respiratory Diseases: Overview. In: S.R. Quah, (Ed.), International Encyclopedia of Public Health, 2nd ed, (pp. 328-331). Massachusetts: Academic Press.
4. 4. Yorgancıoğlu, A., Türktaş, H., Kalaycı, O., Yardım, N., Buzgan, T., Kocabaş, A. et al. (2009). The WHO global alliance against chronic respiratory diseases in Turkey (GARD Turkey). Tüberküloz ve Toraks 2009, 57(4), 439-452.
5. 5. Ram, A., Joseph, D.A., Balachandar, S., Singh, V.P. (2009). Medicinal plants from Siddha system of medicine useful for treating respiratory diseases. International Journal of Pharmaceuticals Analysis, 1, 20-30.
6. 6. Asadbeigi, M., Mohammadi, T., Rafieian-Kopaei, M., Saki, K., Bahmani, M., Delfan, M. (2014). Traditional effects of medicinal plants in the treatment of respiratory diseases and disorders: An ethnobotanical study in the Urmia. Asian Pacific Journal of Tropical Medicine, 7, 364-368.
7. 7. Baytop, T. (1999). Türkiye'de Bitkiler ile Tedavi Geçmişte ve Bugün, 2. Baskı, Nobel Tıp Kitabevleri, İstanbul, p. 480.
8. 8. Ernst, E., Fugh-Berman, A. (2002). Complementary and alternative medicine: What is it all about? Occupational and Environmental Medicine, 59(2), 140-144.

9. 9. Algier, L.A., Hanoğlu, Z., Özden, G., Kara, F. (2005). The use of complementary and alternative (non-conventional) medicine in cancer patients in Turkey. European Journal of Oncology Nursing, 9(2), 138–146.
10. 10. Orhan, F., Sekerel, B.E., Kocabaş, C.N., Saçkesen, C., Adalıoğlu, G., Tuncer, A. (2003). Complementary and alternative medicine in children with asthma. Annals of Allergy, Asthma & Immunology, 90(6), 611-615.
11. 11. Özçelik, G., Toprak, D. (2015). Bitkisel tedavi neden tercih ediliyor? Ankara Medical Journal, 15(2), 48-58.
12. 12. Şahin, S. (2017). Geleneksel, tamamlayıcı, alternatif tıp uygulamalarına genel bir bakış. Türkiye Aile Hekimliği Dergisi, 21(4), 159-162.
13. 13. Güner, A., Aslan, S., Ekim, T., Vural, M., Babaç, M.T. (2012). Türkiye Bitkileri Listesi (Damarlı Bitkiler), Nezahat Gökyiğit Botanik Bahçesi ve Flora Araştırmaları Derneği Yayınları, İstanbul.
14. 14. Erarslan, Z.B., Kültür, Ş. (2019). Ethnoveterinary medicine in Turkey: a comprehensive review. Turkish Journal of Veterinary and Animal Sciences, 43, 555-582.
15. 15. World Health Organization. (2000). General Guidelines for Methodologies in Research and Evaluation of Traditional Medicine. WHO, Geneva. Retrieved January 10, 2020, from https://apps.who.int/iris/bitstream/handle/10665/66783/WHO_EDM_TRM_2000.1.pdf;jsessionid=49650F6C9D1791B7BCBF79D6F8CF2837?sequence=1
16. 16. Ekor, M. (2014). The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Frontiers in Pharmacology, 4, 1-10.
17. 17. Şarışen, O., Çalışkan, D. (2005). Fitoterapi: Bitkilerle Tedaviye Dikkat. Journal of Contemporary Medical Education, 8(14), 182-187.
18. 18. Kalyoncu, A.F., Selçuk, Z.T., İskendarani, A., Coplu, L., Emri, S., Şahin, A.A., Barış, Y.I. (1992). Alternative and complementary medicine for asthma. Thorax, 47, 762.
19. 19. Doğu, G., Kargı, A., Tanrıverdi, Ö., Yaren, A., Demiray, G., Taşköylü, B.Y., Ergin, A. (2014). Complementary/Alternative medicine experience in cancer patients: A questionnaire-based survey. International Journal of Hematology and Oncology, 24, 1-10.
20. 20. Blanc, P.D., Trupin, L., Earnest, G., Katz, P.P., Yelin, E.H., Eisner, M.D. (2001). Alternative therapies among adults with a reported diagnosis of asthma or rhinosinusitis. Chest, 120(5), 1461-1467.
21. 21. Feldman, R.H., Laura, R. (2004). The use of complementary and alternative medicine practices among australian university students. Complementary Health Practice Review, 9(3), 173-179.
22. 22. Chang, K.H., Brodie, R., Choong, M.A., Sweeney, K.J., Kerin, M.J. (2011). Complementary and alternative medicine use in oncology: A questionnaire survey of patients and health care professionals. BMC Cancer, 11(1), 1-9.
23. 23. Chung, Y., Dumont, R.C. (2011). Complementary and alternative therapies: Use in pediatric pulmonary medicine. Pediatric Pulmonology, 46(6), 530-544.
24. 24. Ziment, I., Tashkin, D.P. (2000). Alternative medicine for allergy and asthma. Journal of Allergy and Clinical Immunology, 106(4), 603-614.
25. 25. Sorkness, R.L. (2009). CAM and Respiratory Disease. Nutrition in Clinical Practice, 24(5), 609-615.
26. 26. Akan, H. (2012). Herbal and nonpharmacological therapies in upper respiratory tract infections. The Journal of Turkish Family Physician, 3, 9-15.
27. 27. Dahima, R., Mishra, S., Rathore, D. (2016). In-vitro antioxidant and reducing potential activity of extracts of Citrus limon and Solanum lycopersicum. Der Pharmacia Lettre, 8, 258-269.
28. 28. González-Molina, E., Domínguez-Perles, R., Moreno, D.A., García-Viguera, C. (2010). Natural bioactive compounds of Citrus limon for food and health. Journal of Pharmaceutical and Biomedical Analysis, 51(2), 327-345.
29. 29. Makni, M., Jemai, R., Kriaa, W., Chtourou, Y., Fetoui, H. (2018). Citrus limon from Tunisia: Phytochemical and physicochemical properties and biological activities. BioMed Research International, 2018, 1-10.
30. 30. Ali, B., Al-Wabel, N.A., Shams, S., Ahamad, A., Khan, S.A., Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine, 5(8), 601-611.
31. 31. De Sousa, A.A.S., Soares, P.M.G., De Almeida, A.N.S., Maia, A.R., De Souza, E.P., Assreuy, A.M.S. (2010). Antispasmodic effect of Mentha piperita essential oil on tracheal smooth muscle of rats. Journal of Ethnopharmacology, 130(2), 433-436.
32. 32. Trevisan, S.C.C., Menezes, A.P.P., Barbalho, S.M., Guiguer, E.L. (2017). Properties of Mentha piperita: A brief review. World Journal of Pharmaceutical and Medical Research, 3(1), 309-313.
33. 33. Sharma, V., Agrawal, R.C. (2013). Glycyrrhiza glabra - A plant for the future. Mintage Journal of Pharmaceutical and Medical Sciences, 2(3), 15-20.
34. 34. Shinwari, Z.K., Khan, I., Naz, S., Hussain, A. (2009). Assessment of antibacterial activity of three plants used in Pakistan to cure respiratory diseases. African Journal of Biotechnology, 8(24), 7082-7086.
35. 35. Kültür, Ş. (2007). Medicinal plants used in Kırklareli Province (Turkey). Journal of Ethnopharmacology, 111(2), 341-364.
36. 36. Yayalacı, Y., Çelik, I., Batı, B. (2013). Hepatoprotective and antioxidant activity of linden (Tilia platyphyllos L.) ınfusion against ethanol-ınduced oxidative stress in rats. The Journal of Membrane Biology, 247(2), 181-188.
37. 37. Chrubasik, C., Roufogalis, B.D., Müller-Ladner, U., Chrubasik, S. (2008). A systematic review on the Rosa canina effect and efficacy profiles. Phytotherapy Research, 22(6), 725-733.
38. 38. Hamidi, S., Vaez, H., Asgharian, P. (2014). Rosa canina as an adjunctive treatment of asthma: A hypothesis. Advances in Bioscience and Clinical Medicine, 3(1), 48-52.
39. 39. Wenzig, E.M., Widowitz, U., Kunert, O., Chrubasik, S., Bucar, F., Knauder, E., Bauer, R. (2008). Phytochemical composition and in vitro pharmacological activity of two rose hip (Rosa canina L.) preparations. Phytomedicine, 15(10), 826-835.
40. 40. Kılınç, F., Demircan, F., Yıldırım, Y., Yılmaz, Z., Pekkolay, Z., Tuzcu, A.K. (2014). Licorice root (licorice) induced evaluation of the 5 patients presenting with hypertension and hypokalemia. Sakarya Medical Journal, 4(4), 186-190.
41. 41. Moghaddasi, M.S., Kashani, H.H. (2012). Ginger (Zingiber officinale): A review. Journal of Medicinal Plants Research, 6(26), 4255-4258.
42. 42. Uzun, M.B., Aykaç, G., Özçelikay, G. (2014). Bitkisel ürünlerin yanlış kullanımı ve zararları. Lokman Hekim Dergisi, 4(3), 1-5.
43. 43. Biçen, C., Elver, Ö., Erdem, E., Kaya, C., Karataş, A., Dilek, M., Akpolat, T. (2012). Hipertansiyon hastalarında bitkisel ürün kullanımı. Journal of Experimental and Clinical Medicine, 29(2), 109-112.
44. 44. Sim, T.F., Sherriff, J., Hattingh, H.L., Parsons, R., Tee, L.B. (2013). The use of herbal medicines during breastfeeding: a population-based survey in Western Australia. BMC Complementary Medicine and Therapies, 13, 1-10.