Biyotikler Ailesinin Yeni Üyesi: Postbiyotikler

Dilara Sak; Günsu Soykut

EN TR

New Member of Biotics Family Postbiotics

Abstract

This review article aimed to evaluate the potential effects of postbiotics on health based on the current literature obtained upon entering the keywords 'postbiotic', 'postbiotic and health' into scientific databases such as Google Scholar, PubMed and ScienceDirect. Postbiotics produced by living microorganisms are expressed as non-living microbial cells, microbial fractions or cell lysates. At the same time, paraprobiotics and fermented infant formulas expressed as postbiotics have many physiological benefits on host health. It shows potential effects that positively affect health in children, adults and the elderly, such as anti-inflammatory, antimicrobial, immunomodulatory, anti-obesogenic, anti-cancer, antioxidant, antihypertensive and hypocholesterolemic properties. It is also thought that postbiotics may provide additional benefits over other microorganisms (probiotics, prebiotics, synbiotics). It is known that postbiotics show these effects locally on the intestinal epithelium and systematically on organs and tissues. There are animal and human studies showing the relationship between postbiotics and health. There is a need for in vitro and in vivo studies in where the effects of postbiotics will be examined in detail (ideal dose, chronic disease relationship, possible side effects, etc.).

Keywords

Postbiotic, Paraprobiotic, Health.

Biyotikler Ailesinin Yeni Üyesi: Postbiyotikler

Abstract

Bu derleme tarzı yazı Google Akademik, PubMed ve ScienceDirect vb. bilimsel veri tabanlarına ‘postbiyotik’, ‘postbiyotik ve sağlık’ anahtar kelimelerinin girilmesi üzerine elde edilen güncel literatürden yola çıkarak postbiyotiklerin sağlık üzerindeki potansiyel etkilerinin değerlendirilmesini hedeflemiştir. Canlı mikroorganizmalar tarafından üretilen postbiyotikler, cansız mikrobiyal hücreler, mikrobiyal fraksiyonlar veya hücre lizatları olarak ifade edilmektedir. Aynı zamanda postbiyotik olarak ifade edilen paraprobiyotikler ve fermente edilmiş bebek formulalarının, konakçı sağlığı üzerinde birçok fizyolojik faydası bulunmaktadır. Çocuklarda, yetişkinlerde ve yaşlılarda anti-inflamatuvar, antimikrobiyal, immünomodülatör, anti-obezojenik, anti-kanser, antioksidan, antihipertansif, hipokolesterolemik gibi sağlığı olumlu yönde etkileyen potansiyel etkiler göstermektedir. Ayrıca postbiyotiklerin diğer mikroorganizmalara (probiyotikler, prebiyotikler, sinbiyotikler) göre ek faydalar sağlayabileceği düşünülmektedir. Postbiyotiklerin bu etkilerini lokal olarak barsak epiteli üzerinden, sistematik olarak organ ve dokular üzerinden gösterdikleri bilinmektedir. Postbiyotiklerin sağlık ile ilişkisini gösteren hayvan ve insan çalışmaları mevcuttur. Postbiyotiklerin etkilerinin detaylı incelendiği (ideal doz, kronik hastalık ilişkisi, olası yan etkileri vb.) in vitro ve in vivo çalışmalara ihtiyaç vardır.

Keywords

postbiyotik, paraprobiyotik, sağlık

References

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Turkish

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Health Care Administration

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Review

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Dilara Sak ^*
0000-0002-1144-194X
Kuzey Kıbrıs Türk Cumhuriyeti

Günsu Soykut
0000-0002-8479-1457
Kuzey Kıbrıs Türk Cumhuriyeti

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December 25, 2021

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April 19, 2021

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July 9, 2021

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https://izlik.org/JA42SH22HZ

APA

Sak, D., & Soykut, G. (2021). Biyotikler Ailesinin Yeni Üyesi: Postbiyotikler. Genel Sağlık Bilimleri Dergisi, 3(3), 259-272. https://izlik.org/JA42SH22HZ

AMA

1.Sak D, Soykut G. Biyotikler Ailesinin Yeni Üyesi: Postbiyotikler. JGEHES. 2021;3(3):259-272. https://izlik.org/JA42SH22HZ

Chicago

Sak, Dilara, and Günsu Soykut. 2021. “Biyotikler Ailesinin Yeni Üyesi: Postbiyotikler”. Genel Sağlık Bilimleri Dergisi 3 (3): 259-72. https://izlik.org/JA42SH22HZ.

EndNote

Sak D, Soykut G (December 1, 2021) Biyotikler Ailesinin Yeni Üyesi: Postbiyotikler. Genel Sağlık Bilimleri Dergisi 3 3 259–272.

IEEE

[1]D. Sak and G. Soykut, “Biyotikler Ailesinin Yeni Üyesi: Postbiyotikler”, JGEHES, vol. 3, no. 3, pp. 259–272, Dec. 2021, [Online]. Available: https://izlik.org/JA42SH22HZ

ISNAD

Sak, Dilara - Soykut, Günsu. “Biyotikler Ailesinin Yeni Üyesi: Postbiyotikler”. Genel Sağlık Bilimleri Dergisi 3/3 (December 1, 2021): 259-272. https://izlik.org/JA42SH22HZ.

JAMA

1.Sak D, Soykut G. Biyotikler Ailesinin Yeni Üyesi: Postbiyotikler. JGEHES. 2021;3:259–272.

MLA

Sak, Dilara, and Günsu Soykut. “Biyotikler Ailesinin Yeni Üyesi: Postbiyotikler”. Genel Sağlık Bilimleri Dergisi, vol. 3, no. 3, Dec. 2021, pp. 259-72, https://izlik.org/JA42SH22HZ.

Vancouver

1.Dilara Sak, Günsu Soykut. Biyotikler Ailesinin Yeni Üyesi: Postbiyotikler. JGEHES [Internet]. 2021 Dec. 1;3(3):259-72. Available from: https://izlik.org/JA42SH22HZ

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New Member of Biotics Family Postbiotics

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Biyotikler Ailesinin Yeni Üyesi: Postbiyotikler

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