j health sci med / jhsm

Journal of Health Sciences and Medicine

2636-8579

MediHealth Academy Yayıncılık

10.32322/jhsm.1188641

Health Care Administration

Sağlık Kurumları Yönetimi

Regulatory immune cells: a review of the novel paradigm of primary Sjogren's syndrome

https://orcid.org/0000-0001-7013-9460

Ucar

Selda

AKDENİZ ÜNİVERSİTESİ

01 12 2023

6 1 215 219 10 13 2022 01 06 2023

2018

Journal of Health Sciences and Medicine

Primary Sjögren's Syndrome (pSS) is an autoimmune disease that mostly affects women. Patients with pSS experience dry mouth and eyes in addition to signs of systemic disease. pSS was considered a Th1 autoimmune disease for many years. However, in various studies, it has been shown that dysregulation of regulatory cells play critical role in the pathogenesis of the disease. This review focuses on studies supporting this view and answers questions about the role of regulatory cells in the pathogenesis of pSS.

Arthritis rheumatoid regulatory T-cells regulatory B-cells primary Sjogren follicular regulatory T-cells

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