Assessment of carotid-intima media thickness in patients with epilepsy receiving antiepileptic drugs

Year 2022, , 234 - 238, 17.01.2022

Mehtap Kocatürk , Özcan Kocatürk

https://doi.org/10.32322/jhsm.1006178

Abstract

Aim: This study aims to investigate whether there is an increase in carotid-intima media thickness (C-IMT) in epilepsy patients using antiepileptic drugs when compared to the normal control group and whether there is a difference when we group them as monotherapy and polytherapy.
Material and Method: 68 people were included in the prospective cross-sectional study. 38 epilepsy and 30 healthy control groups that were matched in terms of demographic characteristics
Results: C-IMT was statistically higher in the epilepsy group (p<0.001). When carotid USG results are analyzed as control, monotherapy, and polytherapy, there was no difference between control and monotherapy, there was statistical significance between the control group and polytherapy (p<0.001), and between monotherapy and polytherapy (p:0.010)
Conclusions: According to our study result, polytherapy should be avoided as much as possible, especially in patients with vascular risk factors.

Keywords

Carotid-Intima media thickness, Epilepsy, Monotherapy-Polytherapy

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