<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20241031//EN"
        "https://jats.nlm.nih.gov/publishing/1.4/JATS-journalpublishing1-4.dtd">
<article  article-type="case-report"        dtd-version="1.4">
            <front>

                <journal-meta>
                                                                <journal-id>j immunol clin microbiol</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Journal of Immunology and Clinical Microbiology</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">2528-9470</issn>
                                                                                            <publisher>
                    <publisher-name>Erkan YULA</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.58854/jicm.1773122</article-id>
                                                                                                                                                                                            <title-group>
                                                                                                                        <article-title>Gemella Morbillorum:  A Rare Cause of Sub Acute Infective Endocarditis</article-title>
                                                                                                                                                                                                <trans-title-group xml:lang="tr">
                                    <trans-title>Gemella Morbillorum:  A Rare Cause of Sub Acute Infective Endocarditis</trans-title>
                                </trans-title-group>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                <name>
                                    <surname>Shanmuga Sundaram</surname>
                                    <given-names>Meenakshi</given-names>
                                </name>
                                                                    <aff>Madras Medical College</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Krishnan</surname>
                                    <given-names>Usha</given-names>
                                </name>
                                                                    <aff>MADRAS MEDICAL COLLEGE</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Arumugam</surname>
                                    <given-names>Vijayalakshmi</given-names>
                                </name>
                                                                    <aff>MADRAS MEDICAL COLLEGE</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>N</surname>
                                    <given-names>Jayaprakash</given-names>
                                </name>
                                                                    <aff>MADRAS MEDICAL COLLEGE</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>T.s</surname>
                                    <given-names>Karthigeyan</given-names>
                                </name>
                                                                    <aff>MADRAS MEDICAL COLLEGE</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Rangasamy</surname>
                                    <given-names>Pavya</given-names>
                                </name>
                                                                    <aff>MADRAS MEDICAL COLLEGE</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20251015">
                    <day>10</day>
                    <month>15</month>
                    <year>2025</year>
                </pub-date>
                                        <volume>10</volume>
                                        <issue>3</issue>
                                        <fpage>68</fpage>
                                        <lpage>71</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20250903">
                        <day>09</day>
                        <month>03</month>
                        <year>2025</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20251009">
                        <day>10</day>
                        <month>09</month>
                        <year>2025</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2016, Journal of Immunology and Clinical Microbiology</copyright-statement>
                    <copyright-year>2016</copyright-year>
                    <copyright-holder>Journal of Immunology and Clinical Microbiology</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Gemella morbillorum is a facultative anaerobic, Gram-positive cocci and are a commensal part of human flora in the oropharynx, gastrointestinal and genitourinary tracts. A case of Gemella morbillorum sub acute infective endocarditis of the mitral valve in a patient with previous history of Rheumatic heart disease with mitral regurgitation is reported. The presentation was subacute, and the infection was complicated with severe mitral valve regurgitation. Blood cultures were positive for a viridans streptococcal species and Gemella morbillorum was identified by VITEK 2 Compact Automated system. Gemella morbillorum infections are very rare, and endocarditis is the most common presentation. G.morbillorum endocarditis is probably under recognized because of its difficulty in identification of the species and has not been reported frequently. In this case report the condition is briefed   and the problems in the identification of the organism by conventional methods are discussed and the need for Automation in identification of pathogen in lab diagnosis is emphasized.</p></abstract>
                                                                                                                                    <trans-abstract xml:lang="tr">
                            <p>Gemella morbillorum is a facultative anaerobic, Gram-positive cocci and are a commensal part of human flora in the oropharynx, gastrointestinal and genitourinary tracts. A case of Gemella morbillorum sub acute infective endocarditis of the mitral valve in a patient with previous history of Rheumatic heart disease with mitral regurgitation is reported. The presentation was subacute, and the infection was complicated with severe mitral valve regurgitation. Blood cultures were positive for a viridans streptococcal species and Gemella morbillorum was identified by VITEK 2 Compact Automated system. Gemella morbillorum infections are very rare, and endocarditis is the most common presentation. G.morbillorum endocarditis is probably under recognized because of its difficulty in identification of the species and has not been reported frequently. In this case report the condition is briefed   and the problems in the identification of the organism by conventional methods are discussed and the need for Automation in identification of pathogen in lab diagnosis is emphasized.</p></trans-abstract>
                                                            
            
                                                            <kwd-group>
                                                    <kwd>Gemella morbillorum</kwd>
                                                    <kwd>  sub-acute Infective endocarditis</kwd>
                                                    <kwd>  Mitral valve</kwd>
                                            </kwd-group>
                                                        
                                                                            <kwd-group xml:lang="tr">
                                                    <kwd>Gemella morbillorum</kwd>
                                                    <kwd>  sub-acute Infective endocarditis</kwd>
                                                    <kwd>  Mitral valve</kwd>
                                            </kwd-group>
                                                                                                            </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">Tunnicliff R. The cultivation of a micrococcus from blood in pre-eruptive and eruptive stages of measles. JAMA 1917; 68:1028–30.</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">Shahani L. Gemella morbillorum prosthetic aortic valve endocarditis BMJ Case Rep 2014. doi:10.1136/bcr-2014-207304</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">Al Soub et al Gemella morbillorum endocarditis. Saudi Med J 2003; Vol. 24 (10): 1135-1137</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">Klipper-Baltz R, Schleifer KH. Transfer of Streptococcus morbillorum to the genus Gemella as Gemella morbillorum comp.nov. Int J Syst Bacteriol 1988; 38: 442-443.</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">Debast SB, Koot R, Meis CA. Infections caused by Gemella morbillorum. Lancet 1993; 342: 560</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">Bernard La Scola And Didier Raoult Molecular Identification of Gemella Species from Three Patients with Endocarditis Journal of Clinical Microbiology, Apr. 1998,p.866-871</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">Berger, U. 1961. A proposed new genus of gram-negative cocci: Gemella. Int. Bull. Bacteriol. Nomencl. Taxon. 11:17±19</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">García López E, Martín-Galiano AJ. The Versatility of Opportunistic Infections Caused by Gemella Isolates Is Supported by the Carriage of Virulence Factors from Multiple Origins. Front Microbiol. 2020 Mar 31; 11:524. doi: 10.3389/fmicb.2020.00524. PMID: 32296407; PMCID: PMC7136413</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">Lopez-DuplaM, Creus C, Navarro O, Raga X. Asssociation of Gemella morbillorum endocarditis with adenomatous polyps and carcinoma of the colon: case report and review. Clin Infect Dis 1996; 22: 379-380.</mixed-citation>
                    </ref>
                                    <ref id="ref10">
                        <label>10</label>
                        <mixed-citation publication-type="journal">Kofteridis DP, Anastasopoulos T, Panagiotakis S, Kontopodis E, Samonis G. Endocarditis caused by Gemella morbillorum resistant to beta-lactams and aminoglycosides. Scand J Infect Dis. 2006;38(11-12):1125-7. doi: 10.1080/00365540600740538. PMID: 17148095</mixed-citation>
                    </ref>
                                    <ref id="ref11">
                        <label>11</label>
                        <mixed-citation publication-type="journal">Cao X, Yuan L. Gemella morbillorum infective endocarditis: A case report and literature review. Open Life Sci. 2023 May 18;18(1):20220599. doi: 10.1515/biol-2022-0599. PMID: 37215499; PMCID: PMC10199321.</mixed-citation>
                    </ref>
                                    <ref id="ref12">
                        <label>12</label>
                        <mixed-citation publication-type="journal">Akiyama K, Taniyasu N, Hirota J, Iba Y, Maisawa K. Recurrent aortic valve endocarditis caused by Gemella morbillorum -report of a case and review of the literature. Jpn Circ J. 2001 Nov;65(11):997-1000. doi: 10.1253/jcj.65.997. PMID: 11716255.</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
