Research Article
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Formulation of Mild Shampoos and Investigation of Possible Prebiotic Effects

Year 2023, Volume: 8 Issue: 4, 100 - 105, 31.12.2023
https://doi.org/10.58854/jicm.1400959

Abstract

Background: Recently, there has been a significant increase in the application of prebiotics in cosmetic products. Thus, this investigation aims to create two mild shampoo compositions, containing inulin; a distinguished prebiotic, and a reference shampoo. As a further step, the efficacy of formulations against strains of Staphylococcus aureus and Staphylococcus epidermidis bacteria, as well as mixed cultures of these two bacteria, was assessed.
Materials and Methods: After formulation development, physicochemical (physical appearance, pH, percentage of solid contents, viscosity, density and stability studies) and biological evaluations (challenge test, MIC (Minimum inhibition concentration), MBC (Minimum Bactericidal Concentration) were carried out.
Results: The results showed that the hair and body shampoo formulas displayed good stability and maintained their physicochemical properties under different conditions over time. Furthermore, they were microbiologically safe according to the challenge test and instrumental analysis. Microbial assays indicated that Shampoo-A promoted the growth of Staphylococcus epidermidis while inhibiting the growth of Staphylococcus aureus in the presence of prebiotic active, whereas Shampoo-B inhibited the growth of both bacteria.
Conclusions: Although further research is required to declare the microbiome-related claims, the development of these products holds promise for positive effects on skin health and microbiome.

References

  • Rademacher M, Zinn MK, Beinio R, et. al. A New Model to Investigate the Effects of Cosmetics on Skin Microorganisms In Vitro. Cosmetics. 2022 Aug 22;9(4):88. DOI: 10.3390/cosmetics9040088
  • Koh LF, Ong RY, Common JE. Skin microbiome of atopic dermatitis. Allergology International. 2022;71(1):31-9. DOI: 10.1016/j.alit.2021.11.001
  • Dréno B, Dagnelie MA, Khammari A, et al. The skin microbiome: a new actor in inflammatory acne. American journal of clinical dermatology. 2020 Sep;21(Suppl 1):18-24. DOI:10.1007/s40257-020-00531- 1
  • Daou H, Paradiso M, Hennessy K, et al. Rosacea and the microbiome: a systematic review. Dermatology and therapy. 2021 Feb;11:1-2. DOI: 10.1007/s13555-020- 00460-1
  • Dapkevicius I, Romualdo V, Marques AC, et al. Acne Vulgaris Topical Therapies: Application of Probiotics as a New Prevention Strategy. Cosmetics. 2023 May 11;10(3):77. DOI: 10.3390/cosmetics10030077
  • Cheon S, Kim G, Bae JH, et al. Comparative analysis of prebiotic effects of four oligosaccharides using in vitro gut model: digestibility, microbiome, and metabolome changes. FEMS Microbiology Ecology. 2023 Feb;99(2):fiad002. DOI: 10.1093/femsec/ fiad002
  • Nizioł-Łukaszewska Z, Bujak T, Wasilewski T, et al. Inulin as an effectiveness and safe ingredient in cosmetics. Polish Journal of Chemical Technology. 2019 Mar;21(1):44-9. DOI: 10.2478/pjct-2019-0008
  • ISO11930 (2019) Cosmetics — Microbiology — Evaluation of the antimicrobial protection of a cosmetic product. https://www.iso.org/ standard/75058.html
  • Wayne PA. Clinical and Laboratory Standards Institute: Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Approved Standard, M07- A9, Clinical and Laboratory Standards Institute 950. 2012
Year 2023, Volume: 8 Issue: 4, 100 - 105, 31.12.2023
https://doi.org/10.58854/jicm.1400959

Abstract

References

  • Rademacher M, Zinn MK, Beinio R, et. al. A New Model to Investigate the Effects of Cosmetics on Skin Microorganisms In Vitro. Cosmetics. 2022 Aug 22;9(4):88. DOI: 10.3390/cosmetics9040088
  • Koh LF, Ong RY, Common JE. Skin microbiome of atopic dermatitis. Allergology International. 2022;71(1):31-9. DOI: 10.1016/j.alit.2021.11.001
  • Dréno B, Dagnelie MA, Khammari A, et al. The skin microbiome: a new actor in inflammatory acne. American journal of clinical dermatology. 2020 Sep;21(Suppl 1):18-24. DOI:10.1007/s40257-020-00531- 1
  • Daou H, Paradiso M, Hennessy K, et al. Rosacea and the microbiome: a systematic review. Dermatology and therapy. 2021 Feb;11:1-2. DOI: 10.1007/s13555-020- 00460-1
  • Dapkevicius I, Romualdo V, Marques AC, et al. Acne Vulgaris Topical Therapies: Application of Probiotics as a New Prevention Strategy. Cosmetics. 2023 May 11;10(3):77. DOI: 10.3390/cosmetics10030077
  • Cheon S, Kim G, Bae JH, et al. Comparative analysis of prebiotic effects of four oligosaccharides using in vitro gut model: digestibility, microbiome, and metabolome changes. FEMS Microbiology Ecology. 2023 Feb;99(2):fiad002. DOI: 10.1093/femsec/ fiad002
  • Nizioł-Łukaszewska Z, Bujak T, Wasilewski T, et al. Inulin as an effectiveness and safe ingredient in cosmetics. Polish Journal of Chemical Technology. 2019 Mar;21(1):44-9. DOI: 10.2478/pjct-2019-0008
  • ISO11930 (2019) Cosmetics — Microbiology — Evaluation of the antimicrobial protection of a cosmetic product. https://www.iso.org/ standard/75058.html
  • Wayne PA. Clinical and Laboratory Standards Institute: Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Approved Standard, M07- A9, Clinical and Laboratory Standards Institute 950. 2012
There are 9 citations in total.

Details

Primary Language English
Subjects Medical Microbiology (Other)
Journal Section Research Articles
Authors

Başak Türk Erbul

Sena Orhan

Burak Saka 0009-0007-6875-2232

Publication Date December 31, 2023
Submission Date December 6, 2023
Acceptance Date December 31, 2023
Published in Issue Year 2023 Volume: 8 Issue: 4

Cite

APA Türk Erbul, B., Orhan, S., & Saka, B. (2023). Formulation of Mild Shampoos and Investigation of Possible Prebiotic Effects. Journal of Immunology and Clinical Microbiology, 8(4), 100-105. https://doi.org/10.58854/jicm.1400959
AMA Türk Erbul B, Orhan S, Saka B. Formulation of Mild Shampoos and Investigation of Possible Prebiotic Effects. J Immunol Clin Microbiol. December 2023;8(4):100-105. doi:10.58854/jicm.1400959
Chicago Türk Erbul, Başak, Sena Orhan, and Burak Saka. “Formulation of Mild Shampoos and Investigation of Possible Prebiotic Effects”. Journal of Immunology and Clinical Microbiology 8, no. 4 (December 2023): 100-105. https://doi.org/10.58854/jicm.1400959.
EndNote Türk Erbul B, Orhan S, Saka B (December 1, 2023) Formulation of Mild Shampoos and Investigation of Possible Prebiotic Effects. Journal of Immunology and Clinical Microbiology 8 4 100–105.
IEEE B. Türk Erbul, S. Orhan, and B. Saka, “Formulation of Mild Shampoos and Investigation of Possible Prebiotic Effects”, J Immunol Clin Microbiol, vol. 8, no. 4, pp. 100–105, 2023, doi: 10.58854/jicm.1400959.
ISNAD Türk Erbul, Başak et al. “Formulation of Mild Shampoos and Investigation of Possible Prebiotic Effects”. Journal of Immunology and Clinical Microbiology 8/4 (December 2023), 100-105. https://doi.org/10.58854/jicm.1400959.
JAMA Türk Erbul B, Orhan S, Saka B. Formulation of Mild Shampoos and Investigation of Possible Prebiotic Effects. J Immunol Clin Microbiol. 2023;8:100–105.
MLA Türk Erbul, Başak et al. “Formulation of Mild Shampoos and Investigation of Possible Prebiotic Effects”. Journal of Immunology and Clinical Microbiology, vol. 8, no. 4, 2023, pp. 100-5, doi:10.58854/jicm.1400959.
Vancouver Türk Erbul B, Orhan S, Saka B. Formulation of Mild Shampoos and Investigation of Possible Prebiotic Effects. J Immunol Clin Microbiol. 2023;8(4):100-5.

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