j. inst. sci. and tech. Journal of the Institute of Science and Technology 2536-4618 Igdir University 10.21597/jist.472241 Chemical Engineering Kimya Mühendisliği Katalizörsüz Ortamda Benzaldehit Türevlerinin Malononitril Eşliğinde Knoevenagel Kondenzasyonu: Disiyano Bileşiklerinin Sentezi İçin Yeşil Kimya Yasalarına Uygun Etkin Bir Yöntem Catalyst Free Knoevenagel Condensation of Benzaldehyde Derivatives with Malononitrile: A Facile and Compatible Method with Green Chemistry Rules for the Synthesis of Dicyano Compounds https://orcid.org/0000-0003-4290-1539 Nişancı Bilal ATATÜRK ÜNİVERSİTESİ 03 01 2019 9 1 500 511 10 19 2018 11 19 2018 Copyright © 2011, Journal of the Institute of Science and Technology 2011 Journal of the Institute of Science and Technology

Buçalışmada aril aldehitlerin malonitril ile katalizörsüz ortamda, sadece çözücü olarak su/metanol karışımıkullanılmasıyla gerçekleştirdiği tepkime sonucu ilgili benzilidenmalononitril türevleri 15 dakikada oda sıcaklığında kantitatifverimlerle elde edilmiştir. Knoevenagel kondenzasyonu ile benzilidenmalononitril bileşiklerinin eldesi ile ilgili literatürde birçokyöntem bulunmasına rağmen, bu çalışmada herhangi bir katalizör kullanılmamasıbu çalışmayı yeşil kimya yasalarına uyan etkin bir yöntem olarak ön planaçıkarmaktadır.

Inthis study, as a result of the reaction of aryl aldehydes with malononitrile in a catalyst-freecondition by using only water/methanol mixture as a solvent, the correspondingbenzylidenemalononitrile derivatives were obtained in quantitative yields atroom temperature just in 15 minutes. Although many methods have been found inthe literature about Knoevenagel Condensation, addressed herein a catalyst freemethodology which is in harmony with the green chemistry rules makes this workeffective than the others.

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