Katalizörsüz Ortamda Benzaldehit Türevlerinin Malononitril Eşliğinde Knoevenagel Kondenzasyonu: Disiyano Bileşiklerinin Sentezi İçin Yeşil Kimya Yasalarına Uygun Etkin Bir Yöntem

Year 2019, Volume: 9 Issue: 1, 500 - 511, 01.03.2019

Bilal Nişancı

https://doi.org/10.21597/jist.472241

Cited By: 2

Abstract

Bu
çalışmada aril aldehitlerin malonitril ile katalizörsüz ortamda, sadece çözücü olarak su/metanol karışımı
kullanılmasıyla gerçekleştirdiği tepkime sonucu ilgili benzilidenmalononitril türevleri 15 dakikada oda sıcaklığında kantitatif
verimlerle elde edilmiştir. Knoevenagel kondenzasyonu ile benzilidenmalononitril bileşiklerinin eldesi ile ilgili literatürde birçok
yöntem bulunmasına rağmen, bu çalışmada herhangi bir katalizör kullanılmaması
bu çalışmayı yeşil kimya yasalarına uyan etkin bir yöntem olarak ön plana
çıkarmaktadır. 

Keywords

Knoevenagel kondenzasyonu, yeşil kimya, malononitril, aldehit

Catalyst Free Knoevenagel Condensation of Benzaldehyde Derivatives with Malononitrile: A Facile and Compatible Method with Green Chemistry Rules for the Synthesis of Dicyano Compounds

Abstract

In
this study, as a result of the reaction of aryl aldehydes with malononitrile in a catalyst-free
condition by using only water/methanol mixture as a solvent, the corresponding
benzylidenemalononitrile derivatives were obtained in quantitative yields at
room temperature just in 15 minutes. Although many methods have been found in
the literature about Knoevenagel Condensation, addressed herein a catalyst free
methodology which is in harmony with the green chemistry rules makes this work
effective than the others. 

Keywords

Knoevenagel Condensation, Green Chemistry, malononitrile, aldehyde

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