Synthesis and Characterization of Enaminone Derivatives of Barbituric Acid

Year 2019, Volume: 9 Issue: 2, 993 - 1003, 01.06.2019

Erkan Fırıncı

https://doi.org/10.21597/jist.442571

Cited By: 1

Abstract

In this study, four enaminones derived from barbituric acid were synthesized with the reaction of 5-formylbarbituric acid and selected primer amines with high yield. The structures of all

compounds were proved by using ATR-FTIR, 1H and 13C NMR spectroscopy. Also, 19F NMR spectroscopy was used for characterization of 2d. The obtained spectroscopic results have complied

with reported similar derivatives in literature.

Keywords

Barbituric acid, Enaminone, Condensation reaction, Spectroscopy

Supporting Institution

Scientific Research Project Unit (BAP) of Aydın Adnan Menderes University

Project Number

FEF-17020

Thanks

This work has been supported financially by “Scientific Research Project Unit (BAP) of Aydın Adnan Menderes University” (Project No: FEF-17020).

Barbitürik Asitin Enaminon Türevlerinin Sentezi ve Karakterizasyonu

Abstract

Bu çalışmada barbitürik asitten türeyen dört enaminon türevi 5-formilbarbitürik asit ve seçilen birincil aminlerin reaksiyonu ile yüksek verimle sentezlenmiştir. Sentezlenen bütün bileşiklerin

yapıları ATR-FTIR, 1H ve 13C NMR spektroskopileri kullanılarak kanıtlanmıştır. Bileşik 2d’nin yapısal karakterizasyonun da ayrıca 19F NMR spektroskopisi kullanılmıştır. Elde edilen spektroskopik

sonuçlar literatürdeki rapor edilmiş benzer türevler ile uyumludur.

Keywords

Barbitürik asit, Enaminon, Kondenzasyon reaksiyonu, Spektroskopi

Project Number

FEF-17020

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