Evaluation of The Different Suture Materials For Tissue Reaction

- , 06.11.2015

Fırat Selvi Sırmahan Çakarer , Taylan Can Serpi İrem Kırlı Topçu Alen Palancıoğlu Başak Keskin Bilge Bilgiç Mehmet Yaltırık Cengizhan Keskin

https://doi.org/10.17096/jiufd.79438

Abstract

Purpose:The purpose of this study was to investigate the healing differences in between four different widely used suture materials in the oral  surgery practice, including silk (Perma-Hand; Ethicon, INC., Somerville, NJ, USA), polypropylene (Prolene; Ethicon, INC.,  Somerville, NJ, USA), coated polyglactin 910 (Ethicon, INC., Somerville, NJ, USA). and polyglecaprone 25 (Ethicon, INC.,  Somerville, NJ, USA ).

Materials and Methods:16 male rats were randomly allocated into two groups depending on their sacrification days (post-operative 1^st and the 7^th days). Four longitudinal incision wounds, each 1cm in size, were created on the dorsum of each animal which were then primarily closed with four different types of sutures.

Results: The effects of these suture materials on soft tissue healing were compared histopathologically, by means of density of the cells, necrosis, fibrosis, foreign body reaction, the presence of  cells of acute and chronic infection. No statistically significant difference was observed between the groups regarding the density of the cells, necrosis, fibrosis, foreign body reaction, and the presence of the cells of acute & chronic infections. Of note, propylene showed slightly less tissue reaction among the other materials.

Conclusion: The ideal suture must be strong, handled easily, and forms secure knots, causing minimal tissue inflammation and must not promote infection. Although no single suture possesses all of these features together, selecting proper material for each surgical intervention will help to achieve better results.

Keywords

Suture materials; soft tissue; surgery; dorsum; rat

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