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ODONTOJENIK KİSTLERDE CEA (KARSİNOEMBRYONİK ANTİJEN) VE EMA (EPİTELYAL MEMBRAN ANTİJEN) İMMUNO-REAKTİVİTESİ-CEA (CARCINOEMBRYONICANTIGEN) AND EMA (EPITHELIAL MEMBRANE ANTIGEN) IMMUNO-REA CTTVITIES IN ODONTOGENIC CYSTS

Year 1994, Volume: 28 Issue: 4, 249 - 253, 31.05.2013

Abstract

ÖZET

Bu çalışmada, Î.Ü. Diş Hek. Fak. Ağız Diş Çene Hast. ve Cerrahisi Anabilim Dalı'na başvuran ve yapılan klinik, radyolojik ve patolojik tetkikleri sonucu keratokist, radiküler kist ve foliküler kist tanısı konan, toplam 30 vak'a immuno-histokimyasal yöntemle çalışarak, karsinoembriyonİk antijen (CEA) ve epitelyal membran antijen (EMA) varlığı açılarından değerlendirildi. Enükle edilen kistlerin histo-patolojik teşhisi İ.Ü. Onkoloji Enstitüsü'nde, immunohis-tokimyasal yöntemle değerlendirilmeleri ise İ.Ü. Cerrahpaşa Tıp Fak. Patoloji Anabilim Dalı'nda yapıldı 5[im kalınlığında hazırlanan kesitlere peroksidaz-antiperoksidaz (PAP) yöntemiyle hem CEA hem de EMA uygulandı. Ke-ratokistlerin tümünde (%100) olmak üzere, sırasıyla foliküler kistler (%60) ve radiküler kistlerde (%20) CEA im-munoreaktivitesi gözlendi. Bu sonuçlara dayanarak, CEA'in kistlerin aggresivliğinin belirlenmesinde, odonto-jenik kistlerde spesifik bir marker olma özelliğine sahip olduğunu vurgulamak istiyoruz.

Anahtar sözcükler: CEA, EMA, odontojen kistler

ABSTRACT

In this research, the patients who were referred to Dental Faculty of Istanbul University, Department of Oral Surgery were evaluated and

30 cases who were diagnosed as keratocyst, radicular and follicular cysts having investigated according to the presence of carcinoembryonic antigen (CEA) and epithelial emmbrane antigen (EMA). The histopathological diagnosis of the cysts have been carried out at the Institute of Oncology of Istanbul University while the immunohistochemical examinations were done at the Pathology Department of Cerrahpaşa

Medical Faculty of Istanbul University. The sections of5(Am. thickness were subjected to both the CEA and EMA by the method of peroxidase-antiperoxidase (PAP). The CEA immunoreac-tivity was observed in all the keratocysts (%100), and in follicular (%60) and radicular (%20) cysts, respectively. Based on the results, we would like to emphasise that the CEA has a chracteristic of being a spesific marker in the determination of aggressive property of odotogenic cysts.

 

Key words: CEA, EMA, odontogenic cysts.

 

 

Year 1994, Volume: 28 Issue: 4, 249 - 253, 31.05.2013

Abstract

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Details

Primary Language Turkish
Journal Section Original Research Articles
Authors

Necla Timoçin This is me

Hülya Koçak This is me

Feriha Öz This is me

Selda Uraz This is me

Publication Date May 31, 2013
Published in Issue Year 1994 Volume: 28 Issue: 4

Cite

APA Timoçin, N., Koçak, H., Öz, F., Uraz, S. (2013). ODONTOJENIK KİSTLERDE CEA (KARSİNOEMBRYONİK ANTİJEN) VE EMA (EPİTELYAL MEMBRAN ANTİJEN) İMMUNO-REAKTİVİTESİ-CEA (CARCINOEMBRYONICANTIGEN) AND EMA (EPITHELIAL MEMBRANE ANTIGEN) IMMUNO-REA CTTVITIES IN ODONTOGENIC CYSTS. Journal of Istanbul University Faculty of Dentistry, 28(4), 249-253.
AMA Timoçin N, Koçak H, Öz F, Uraz S. ODONTOJENIK KİSTLERDE CEA (KARSİNOEMBRYONİK ANTİJEN) VE EMA (EPİTELYAL MEMBRAN ANTİJEN) İMMUNO-REAKTİVİTESİ-CEA (CARCINOEMBRYONICANTIGEN) AND EMA (EPITHELIAL MEMBRANE ANTIGEN) IMMUNO-REA CTTVITIES IN ODONTOGENIC CYSTS. J Istanbul Univ Fac Dent. May 2013;28(4):249-253.
Chicago Timoçin, Necla, Hülya Koçak, Feriha Öz, and Selda Uraz. “ODONTOJENIK KİSTLERDE CEA (KARSİNOEMBRYONİK ANTİJEN) VE EMA (EPİTELYAL MEMBRAN ANTİJEN) İMMUNO-REAKTİVİTESİ-CEA (CARCINOEMBRYONICANTIGEN) AND EMA (EPITHELIAL MEMBRANE ANTIGEN) IMMUNO-REA CTTVITIES IN ODONTOGENIC CYSTS”. Journal of Istanbul University Faculty of Dentistry 28, no. 4 (May 2013): 249-53.
EndNote Timoçin N, Koçak H, Öz F, Uraz S (May 1, 2013) ODONTOJENIK KİSTLERDE CEA (KARSİNOEMBRYONİK ANTİJEN) VE EMA (EPİTELYAL MEMBRAN ANTİJEN) İMMUNO-REAKTİVİTESİ-CEA (CARCINOEMBRYONICANTIGEN) AND EMA (EPITHELIAL MEMBRANE ANTIGEN) IMMUNO-REA CTTVITIES IN ODONTOGENIC CYSTS. Journal of Istanbul University Faculty of Dentistry 28 4 249–253.
IEEE N. Timoçin, H. Koçak, F. Öz, and S. Uraz, “ODONTOJENIK KİSTLERDE CEA (KARSİNOEMBRYONİK ANTİJEN) VE EMA (EPİTELYAL MEMBRAN ANTİJEN) İMMUNO-REAKTİVİTESİ-CEA (CARCINOEMBRYONICANTIGEN) AND EMA (EPITHELIAL MEMBRANE ANTIGEN) IMMUNO-REA CTTVITIES IN ODONTOGENIC CYSTS”, J Istanbul Univ Fac Dent, vol. 28, no. 4, pp. 249–253, 2013.
ISNAD Timoçin, Necla et al. “ODONTOJENIK KİSTLERDE CEA (KARSİNOEMBRYONİK ANTİJEN) VE EMA (EPİTELYAL MEMBRAN ANTİJEN) İMMUNO-REAKTİVİTESİ-CEA (CARCINOEMBRYONICANTIGEN) AND EMA (EPITHELIAL MEMBRANE ANTIGEN) IMMUNO-REA CTTVITIES IN ODONTOGENIC CYSTS”. Journal of Istanbul University Faculty of Dentistry 28/4 (May 2013), 249-253.
JAMA Timoçin N, Koçak H, Öz F, Uraz S. ODONTOJENIK KİSTLERDE CEA (KARSİNOEMBRYONİK ANTİJEN) VE EMA (EPİTELYAL MEMBRAN ANTİJEN) İMMUNO-REAKTİVİTESİ-CEA (CARCINOEMBRYONICANTIGEN) AND EMA (EPITHELIAL MEMBRANE ANTIGEN) IMMUNO-REA CTTVITIES IN ODONTOGENIC CYSTS. J Istanbul Univ Fac Dent. 2013;28:249–253.
MLA Timoçin, Necla et al. “ODONTOJENIK KİSTLERDE CEA (KARSİNOEMBRYONİK ANTİJEN) VE EMA (EPİTELYAL MEMBRAN ANTİJEN) İMMUNO-REAKTİVİTESİ-CEA (CARCINOEMBRYONICANTIGEN) AND EMA (EPITHELIAL MEMBRANE ANTIGEN) IMMUNO-REA CTTVITIES IN ODONTOGENIC CYSTS”. Journal of Istanbul University Faculty of Dentistry, vol. 28, no. 4, 2013, pp. 249-53.
Vancouver Timoçin N, Koçak H, Öz F, Uraz S. ODONTOJENIK KİSTLERDE CEA (KARSİNOEMBRYONİK ANTİJEN) VE EMA (EPİTELYAL MEMBRAN ANTİJEN) İMMUNO-REAKTİVİTESİ-CEA (CARCINOEMBRYONICANTIGEN) AND EMA (EPITHELIAL MEMBRANE ANTIGEN) IMMUNO-REA CTTVITIES IN ODONTOGENIC CYSTS. J Istanbul Univ Fac Dent. 2013;28(4):249-53.