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Disseminated Nocardiosis in an Immunocompetent Adult: Diagnostic Challenges

Year 2019, Volume: 09 Issue: 01, 46 - 50, 15.03.2019
https://doi.org/10.5799/jmid.537170

Abstract

Nocardiosis
is an opportunistic infection seen in people with impaired host defenses
usually cell mediated immunity. It can involve a single organ or present as
disseminated infection affecting multiple organ systems. We are reporting a
case of 60 year old; an immunocompetent female presented with fever, cough,
skin lesions and altered sensorium. Thorough systemic examination coupled with
meticulous etiological work up including gram stain, acid fast staining and
culture established the definite diagnosis of Nocardiosis. This case highlights
the utility of clinical suspicion and early microbiological detection for
diagnosing such uncommon condition presenting with common clinical symptoms and
multisystem involvement in an immunocompetent patient
J
Microbiol Infect Dis 2019; 9(1): 46-50.

References

  • 1. Lerner PI. Nocardiosis. Clin Infect Dis 1996; 22:891-905. 2. Brown JM, McNeil MM. Nocardia, Rhodococcus, gordonia, actinomadura, streptomyces, and other aerobic actinomycetes. In: Murray PR, Baron EJ, Pfaller MA, et al. editors. Manual of Clinical Microbiology, 8th edn. Washington, D.C: American Society for Microbiology; 2003:502-531. 3. Rodríguez-Nava V, Couble A, Devulder G, Flandrois JP, Boiron P, Laurent F. Use of PCR-Restriction Enzyme Pattern Analysis and Sequencing Database for hsp65 GeneBased Identification of Nocardia Species. J Clin Microbiol 2006; 44:536-546. 4. Yu S, Wang J, Fang Q, Zhang J, Yan F. Specfic clinical manifestations of Nocardia: A case report and literature review. Exp Ther Med 2016; 12(4): 2021-2026. 5. Harrison’s Principles of Internal Medicine 19th/e. Section 7: Miscellaneous bacterial infections, 199 Nocardiosis,Gregory A. Filice; 1084-1088. 6. Mootsikapun P, Intarapoka B, Liawnoraset W. Nocardiosis in Srinagarind Hospital, Thailand: Review of 70 cases from 1996-2001. Int J Infect Dis. 2005; 9:154-158. 7. Kageyama A, Yazawa K, Ishikawa J, Hotta K, Nishimura K, Mikami Y. Nocardial infections in Japan from 1992 to 2001, including the first report of infection by Nocardia transvalensis. Eur J Epidemiol. 2004; 19:383-389. 8. Kennedy KJ, Chung KH, Bowden FJ, et al. A cluster of nocardial brain abscesses. SurgNeurol 2007; 68:43-49. 9. Kumar VA, Augustine D, Panikar D, et al. Nocardia farcinica brain abscess: Epidemiology, pathophysiology, and literature review. Surg Infect (Larchmt) 2014; 15:640-646. 10. Sud S, Buxi T, Anand I, Rohatgi A. Case series: Nocardiosis of the brain and lungs. Indian J Radiol Imaging 2008; 18: 218-21. 11. Wilson JW. Nocardiosis: Updates and Clinical Overview. Mayo Clin Proc 2012; 87(4):403-407 12. Chaudhari M, Renjen PN, Sardana R, Butta H. Nocardia Farcinica brain abcess in an immunocompetent old patient: Acase report and review of literature. Ann Indian Acad Neurol 2017; 20:399-402.
Year 2019, Volume: 09 Issue: 01, 46 - 50, 15.03.2019
https://doi.org/10.5799/jmid.537170

Abstract

References

  • 1. Lerner PI. Nocardiosis. Clin Infect Dis 1996; 22:891-905. 2. Brown JM, McNeil MM. Nocardia, Rhodococcus, gordonia, actinomadura, streptomyces, and other aerobic actinomycetes. In: Murray PR, Baron EJ, Pfaller MA, et al. editors. Manual of Clinical Microbiology, 8th edn. Washington, D.C: American Society for Microbiology; 2003:502-531. 3. Rodríguez-Nava V, Couble A, Devulder G, Flandrois JP, Boiron P, Laurent F. Use of PCR-Restriction Enzyme Pattern Analysis and Sequencing Database for hsp65 GeneBased Identification of Nocardia Species. J Clin Microbiol 2006; 44:536-546. 4. Yu S, Wang J, Fang Q, Zhang J, Yan F. Specfic clinical manifestations of Nocardia: A case report and literature review. Exp Ther Med 2016; 12(4): 2021-2026. 5. Harrison’s Principles of Internal Medicine 19th/e. Section 7: Miscellaneous bacterial infections, 199 Nocardiosis,Gregory A. Filice; 1084-1088. 6. Mootsikapun P, Intarapoka B, Liawnoraset W. Nocardiosis in Srinagarind Hospital, Thailand: Review of 70 cases from 1996-2001. Int J Infect Dis. 2005; 9:154-158. 7. Kageyama A, Yazawa K, Ishikawa J, Hotta K, Nishimura K, Mikami Y. Nocardial infections in Japan from 1992 to 2001, including the first report of infection by Nocardia transvalensis. Eur J Epidemiol. 2004; 19:383-389. 8. Kennedy KJ, Chung KH, Bowden FJ, et al. A cluster of nocardial brain abscesses. SurgNeurol 2007; 68:43-49. 9. Kumar VA, Augustine D, Panikar D, et al. Nocardia farcinica brain abscess: Epidemiology, pathophysiology, and literature review. Surg Infect (Larchmt) 2014; 15:640-646. 10. Sud S, Buxi T, Anand I, Rohatgi A. Case series: Nocardiosis of the brain and lungs. Indian J Radiol Imaging 2008; 18: 218-21. 11. Wilson JW. Nocardiosis: Updates and Clinical Overview. Mayo Clin Proc 2012; 87(4):403-407 12. Chaudhari M, Renjen PN, Sardana R, Butta H. Nocardia Farcinica brain abcess in an immunocompetent old patient: Acase report and review of literature. Ann Indian Acad Neurol 2017; 20:399-402.
There are 1 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Report
Authors

B Saroj Kumar Prusti This is me

Publication Date March 15, 2019
Published in Issue Year 2019 Volume: 09 Issue: 01

Cite

APA Prusti, B. S. K. (2019). Disseminated Nocardiosis in an Immunocompetent Adult: Diagnostic Challenges. Journal of Microbiology and Infectious Diseases, 09(01), 46-50. https://doi.org/10.5799/jmid.537170
AMA Prusti BSK. Disseminated Nocardiosis in an Immunocompetent Adult: Diagnostic Challenges. J Microbil Infect Dis. March 2019;09(01):46-50. doi:10.5799/jmid.537170
Chicago Prusti, B Saroj Kumar. “Disseminated Nocardiosis in an Immunocompetent Adult: Diagnostic Challenges”. Journal of Microbiology and Infectious Diseases 09, no. 01 (March 2019): 46-50. https://doi.org/10.5799/jmid.537170.
EndNote Prusti BSK (March 1, 2019) Disseminated Nocardiosis in an Immunocompetent Adult: Diagnostic Challenges. Journal of Microbiology and Infectious Diseases 09 01 46–50.
IEEE B. S. K. Prusti, “Disseminated Nocardiosis in an Immunocompetent Adult: Diagnostic Challenges”, J Microbil Infect Dis, vol. 09, no. 01, pp. 46–50, 2019, doi: 10.5799/jmid.537170.
ISNAD Prusti, B Saroj Kumar. “Disseminated Nocardiosis in an Immunocompetent Adult: Diagnostic Challenges”. Journal of Microbiology and Infectious Diseases 09/01 (March 2019), 46-50. https://doi.org/10.5799/jmid.537170.
JAMA Prusti BSK. Disseminated Nocardiosis in an Immunocompetent Adult: Diagnostic Challenges. J Microbil Infect Dis. 2019;09:46–50.
MLA Prusti, B Saroj Kumar. “Disseminated Nocardiosis in an Immunocompetent Adult: Diagnostic Challenges”. Journal of Microbiology and Infectious Diseases, vol. 09, no. 01, 2019, pp. 46-50, doi:10.5799/jmid.537170.
Vancouver Prusti BSK. Disseminated Nocardiosis in an Immunocompetent Adult: Diagnostic Challenges. J Microbil Infect Dis. 2019;09(01):46-50.