Current trends and possible therapeutic options against COVID-19

Uzair Ahmed; Usman Ali Ashfaq; Saba Khaliq; Muhammad Qasim; Shah Jahan; Muhammad Shareef Masoud

doi:10.5799/jmid.790198

Review

Year 2020, Volume: 10 Issue: 03, 110 - 120, 15.09.2020

Uzair Ahmed Usman Ali Ashfaq Saba Khaliq Muhammad Qasim Shah Jahan Muhammad Shareef Masoud

https://doi.org/10.5799/jmid.790198

Cited By: 1

Abstract

References

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Current trends and possible therapeutic options against COVID-19

Year 2020, Volume: 10 Issue: 03, 110 - 120, 15.09.2020

Uzair Ahmed Usman Ali Ashfaq Saba Khaliq Muhammad Qasim Shah Jahan Muhammad Shareef Masoud

https://doi.org/10.5799/jmid.790198

Cited By: 1

Abstract

COVID-19 is a highly contagious disease, caused by SARS-CoV-2, which can be transmitted from person to person. SARS-CoV-2 has thought to be originated in bats and transmitted to humans. SARS-CoV-2 has ssRNA genome that is about 30kb in length and it enters lung epithelial cells using spikes (S) by binding with Angiotensin‐converting enzyme 2 (ACE-2). Till date, there is no definitive treatment available for COVID-19 and currently, only symptomatic treatments are available. There is no vaccine developed to combat COVID-19 but scientists are working on developing different types of vaccines including nucleic acid vaccines, subunit vaccines and whole virus vaccines, that are effective and safe to use. Broad spectrum antivirals like ribavirin, lopinavir, ritonavir, arbidol, favipiravir, remdesivir are being test to lessen the viral load. Recently, ivermectin (anti-parasitic drug), has been administered in vitro and showed 99.8% reduction in SARS-CoV-2 in cultured cells in 48 hours. Convalescent plasma (CP) treatments are also being used in order to treat critical cases, nevertheless, no drug has been approved yet. This review focuses on the transmission, clinical features, prevention, current treatments and future possible approaches that can be used to develop therapeutic options against COVID-19. J Microbiol Infect Dis 2019; 9(3):110-120.

Keywords

SARS-CoV-2, clinical features, therapeutic options, antivirals, vaccines

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There are 89 citations in total.

Details

Primary Language	English
Subjects	Health Care Administration
Journal Section	Review
Authors	Uzair Ahmed This is me Usman Ali Ashfaq This is me Saba Khaliq This is me Muhammad Qasim This is me Shah Jahan This is me Muhammad Shareef Masoud This is me
Publication Date	September 15, 2020
Published in Issue	Year 2020 Volume: 10 Issue: 03

Cite

APA	Ahmed, U., Ashfaq, U. A., Khaliq, S., Qasim, M., et al. (2020). Current trends and possible therapeutic options against COVID-19. Journal of Microbiology and Infectious Diseases, 10(03), 110-120. https://doi.org/10.5799/jmid.790198
AMA	Ahmed U, Ashfaq UA, Khaliq S, Qasim M, Jahan S, Masoud MS. Current trends and possible therapeutic options against COVID-19. J Microbil Infect Dis. September 2020;10(03):110-120. doi:10.5799/jmid.790198
Chicago	Ahmed, Uzair, Usman Ali Ashfaq, Saba Khaliq, Muhammad Qasim, Shah Jahan, and Muhammad Shareef Masoud. “Current Trends and Possible Therapeutic Options Against COVID-19”. Journal of Microbiology and Infectious Diseases 10, no. 03 (September 2020): 110-20. https://doi.org/10.5799/jmid.790198.
EndNote	Ahmed U, Ashfaq UA, Khaliq S, Qasim M, Jahan S, Masoud MS (September 1, 2020) Current trends and possible therapeutic options against COVID-19. Journal of Microbiology and Infectious Diseases 10 03 110–120.
IEEE	U. Ahmed, U. A. Ashfaq, S. Khaliq, M. Qasim, S. Jahan, and M. S. Masoud, “Current trends and possible therapeutic options against COVID-19”, J Microbil Infect Dis, vol. 10, no. 03, pp. 110–120, 2020, doi: 10.5799/jmid.790198.
ISNAD	Ahmed, Uzair et al. “Current Trends and Possible Therapeutic Options Against COVID-19”. Journal of Microbiology and Infectious Diseases 10/03 (September 2020), 110-120. https://doi.org/10.5799/jmid.790198.
JAMA	Ahmed U, Ashfaq UA, Khaliq S, Qasim M, Jahan S, Masoud MS. Current trends and possible therapeutic options against COVID-19. J Microbil Infect Dis. 2020;10:110–120.
MLA	Ahmed, Uzair et al. “Current Trends and Possible Therapeutic Options Against COVID-19”. Journal of Microbiology and Infectious Diseases, vol. 10, no. 03, 2020, pp. 110-2, doi:10.5799/jmid.790198.
Vancouver	Ahmed U, Ashfaq UA, Khaliq S, Qasim M, Jahan S, Masoud MS. Current trends and possible therapeutic options against COVID-19. J Microbil Infect Dis. 2020;10(03):110-2.

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