jnbs The Journal of Neurobehavioral Sciences 2149-1909 2148-4325 Uskudar University 10.32739/jnbs.13.1.285 Psychiatry Psikiyatri Alcohol, Substance and Nicotine Use in Adults having Obsessive-Compulsive Disorder Comorbid with Tic Disorder Tik bozukluğuyla komorbid obsesif kompulsif bozukluğu olan erişkinlerde alkol, madde ve nikotin kullanımı https://orcid.org/0000-0002-8056-6244 Tan Oğuz ÜSKÜDAR ÜNİVERSİTESİ https://orcid.org/0000-0001-9197-2240 Çoban Deniz Adnan Antalya Belek Üniversitesi 03 31 2026 13 1 25 29 07 03 2025 03 23 2026 Copyright © 2014, The Journal of Neurobehavioral Sciences 2014 The Journal of Neurobehavioral Sciences

Few studies have investigated the effect of tic disorder (TD) co-occurring with obsessive-compulsive disorder (OCD) on smoking, alcohol use disorders (AUD) and substance use disorders (SUD). We detected lifetime TD, smoking and AUD/SUD in 559 adults with OCD and questioned sociodemographic variables involving adult life including educational achievement, unemployment rate, marital status and suicide attempts (SA). Fifty-four patients (9.66%) had current or past TD. Individuals with and without TD had similar prevalence of AUD/SUD and smoking and similar severity of OCD, anxiety and depressive symptoms. OCD+TD group was characterized by early onset of OCD, male predominance and low percentage of the married. Years of education, unemployment rate and history of SA did not show any difference. TD accompanying OCD in adults has no aggravating impact on the severity of OCD, on predisposition to harmful substances, on educational attainment, unemployment rate, and history of SA whereas marital status is seriously influenced.

Obsesif kompulsif bozukluğa (OKB) eşlik eden tik bozukluğunun (TB) sigara kullanımı, alkol kullanım bozukluğu (AKB) ve madde kullanım bozukluğu (MKB) üzerindeki etkisini inceleyen çalışma sayısı sınırlıdır. Bu kesitsel gözlemsel çalışmada, tik bozukluğu olan ya da olmayan toplam 559 OKB tanılı yetişkinde sigara kullanımı ve AKB/MKB sıklığını araştırdık. Ek olarak eğitim düzeyi, işsizlik, evlilik durumu ve intihar girişimi öyküsü gibi yetişkinlik yaşamına ilişkin parametreleri sorguladık. Katılımcıların 54’ünde (%9,66) çalışma sırasında ya da geçmişte TB mevcuttu. TB olan ve olmayan bireyler AKB/MKB ve sigara kullanımı sıklığı ile OKB, anksiyete ve depresyon belirtilerinin şiddeti açısından benzerdi. OKB+TB grubunda OKB daha erken başlangıçlıydı, ayrıca erkek baskınlığı ve düşük evlilik prevalansı dikkat çekiyordu. Eğitim düzeyi, işsizlik oranı ve intihar girişimi öyküsü açısından anlamlı bir fark bulunmadı. Erişkin OKB hastalarında TB komorbiditesi OKB şiddetini, zararlı madde kullanımına yatkınlığı, eğitim düzeyini, işsizlik oranını veya intihar girişimi öyküsünü artırmamaktadır. Ancak evlilik durumu üzerinde anlamlı bir etkisi bulunmaktadır.

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