Abstract
Objective: The impact of fascia lata on neochondrogenesis placed between both leaflets of the perichondrium after full thickness submucoperichondrial cartilage resection was investigated in a rabbit septum model. Methods: Twenty adult New Zealand rabbits were studied in two groups with equal number of animals in each group. Full thickness cartilage with an area of 1 cm² was resected to create a cartilage defect in all rabbits. Autogenous fascia lata was interposed between both leaflets of the perichondrium and the surgical field was closed (fascia lata group). Any material was not interposed between both leaflets of the perichondrium of the defective area (control group). Rabbits were sacrificed on postoperative 90th days and their septa were totally excised. Neochondrogenesis was investigated histopathologically with a light microscope. The preparations were evaluated as for thickness of newly formed cartilage (in mm), inflammatory reaction and presence of macroscopic perforation. Results: Thickness of the cartilage in the fascia lata group was significantly greater than that of the control group (M-W-U=15,000, p
Keywords
References
- Lawrence WT, Potenza MS. Tissue transfer: fat, dermal, mus- cle, cartilage and fascial grafts. In: Cohen M, Goldwyn RM edi- tor. Mastery of Plastic and Reconstructive Surgery. Vol. 1. London: Little, Brown and Company; 1994. p .88-94.
- Brent, B. Repair and grafting of cartilage and perichondrium. In: McCarthy, JG, editor. Plastic surgery. Philadelphia: W. B. Saunders Co.; 1990. p. 559-80.
- Silver FH, Glasgold AI. Cartilage wound healing. An overview. Otolaryngol Clin North Am 1995;28:847-64.
- Gherardini G, Bathia N, Stal S. Costal cartilage grafts. In: Evans GRD, editor. Operative plastic surgery. New York: Mc Graw- Hill Company; 2000. p. 76-89.
- Özbek S, Şen C, Kahveci Z, Özcan M. The effect of heterolo- gous collagen in neochondrogenesis from free perichondrial grafts, in rabbits: an experimental study. [Article in Turkish] Ulus Travma Acil Cerrahi Derg 2003;9:17-22.
- Duynstee MLG, Verwoed-Verhoef HL, Verwoed CDA, et al. The Dual role of perichondrium in cartilage wound healing. Plast Reconstr Surg 2002;110:1073-9.
- Lester CW. Tissue replacement after subperichondrial resection of costal cartilage: two case reports. Plast Reconstr Surg Transplant Bull 1959;23:49-54.
- Skoog T, Johansson SH. The formation of articuler cartilage from free perichondrial grafts. Plast Reconstr Surg 1976;57:1-6.
- Bruns J, Kertsen P, Lierse W, Weiss A, Silbermann M. The in vitro influence of different culture conditions on the potential of sheep rib perichondrium to form hyaline-like cartilage. Evaluation of gluing materials used for in vivo graft fixation. Wirchows Archiv 1994;424:169-75.
- Silverstein LH, Kraft JD, Wand R. Bone regeneration and tissue acceptance of human fascia lata grafts adjacent to dental implants: a preliminarycase report. J Oral Implantol 1992;18: 394-8.
- Krol R, Barcew-Wiszniewska B. Morphological evaluation of fascia lata tissue implantation for chondral defects in the knee joint of sheep under active motion and load. [Article in Polish] Chir Narzadow Ruchu Ortop Pol 1991;56:129-33.
- Bruno de Rezende Pinna, João Norberto Stavale, Paulo Augusto de Lima Pontes, Osíris de Oliveira Camponês do Brasil. Histological analysis of autologous fascia graft implantation into the rabbit voice muscle. Braz J Otorhinolaryngol 2011;77:185-90.
- Yildirim G, Onar V, Sayin I, Onol SD, Aydin T. The recon- struction of nasal septal perforation with high density porous polyethylene covered with fascia lata: an experimental study on rabbit model. Clin Exp Otorhinolaryngol 2011;4:137-41.
- Hosokawa K, Hata Y, Yano K, Matsuka K, Ito O. Inhibitory effect of mature cartilage on perichondrial neochondrogenesis. Ann Plast Surg 1989;23:155-8.
- Ito Y, Fitzsimmons JS, Sanyal A, Mello MA, Mukherjee N, O’Driscoll SW. Localization of chondrocyte precursors in periosteum. Osteoarthritis Cartilage 2001;9:215-23.
- Hosokawa K, Hata Y, Yano K, Matsuka K. Cartilage formation from perichondrium in a difusion chamber. Ann Plast Surg 1988;21:140-2.
- Lopez Aguado D, Monserrat JR, Perez Piñero B, Campos Bañales ME, Gutierrez R, Diaz Flores L. Neochondrogenesis in the septal area after submucous cartilaginous resection. Acta Otolaryngol 1992;112:539-44.
- Robenson D, Nevo Z. Articuler cartilage chondrocytes are more advantageous for regenerating hyaline-like cartilage than mes- enchymal cells isolated from microfracture repairs. Cell Tissue Bank 2001;2:23-30.
- Caplan AI, Elyaderani M, Mochizuki Y, Wakitani S, Goldberg VM. Principles of cartilage repair and regeneration. Clin Orthop Relat Res 1997;(342):254-69.
- Thammavaram KV1, Benzel EC, Kesterson L. Fascia lata graft as a dural substitute in neurosurgery. South Med J 1990;83:634-6.
- Fitzgerald MP, Mollenhauer J, Brubaker L. The antigenicity of fascia lata allografts. BJU Int 2000;86:826-8.
- Ghoniem GM. Allograft sling material: is it the state of the art? Int Urogynecol J Pelvic Floor Dysfunct 2000;11:69-70.
- This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY
- NC-ND0) Licence (http://creativecommons.org/licenses/by-nc-nd/3.0/) which permits unrestricted noncommercial use, distribution, and reproduc
- tion in any medium, provided the original work is properly cited.
- Please cite this article as: Yılmaz Ş, Bilkay Ö, Özdemir ‹, Avcı A, Adadan Güvenç I. Investigation of the effects of fascia lata on neochondrogenesis in
- a rabbit model. J Med Updates 2014;4(2):66-70.
Abstract
Amaç: Submukoperikondrial tam kat kıkırdak rezeksiyonu sonrası her iki perikondrium yaprağı arasına konan fasia latanın neokondrogenezis üzerine olan etkilerinin araştırılması. Yöntem: Yirmi adet genç erişkin Yeni Zelanda tavşanı eşit sayıda iki gruba ayrıldı. Her tavşanın nazal septumlarından 1 cm²'lik tam kat kıkırdak rezeksiyonu yapıldı. Oluşan kıkırdak defektine ilk grupta tavşanın kendisinden alınan fasia lata submukoperikondrial olarak yerleştirildi (fasia lata grubu). Diğer gruba herhangi bir materyal konmadı (kontrol grubu). Operasyon sonrası 90. günde defekt bölgesini de içine alacak şekilde subtotal septum rezeksiyonu yapıldı. Yeni kıkırdak oluşumu histopatolojik olarak, ışık mikroskobuyla incelendi. Değerlendirmede perikondrium kökenli yeni kıkırdak oluşumu, iltihabi reaksiyon ve nekroz, makroskopik olarak da perforasyon oluşumu göz önüne alındı. Bulgular: Fasia lata yerleştirilen çalışma grubunda oluşan yeni kıkırdak dokusu kontrol grubuna oranla anlamlı derecede fazla bulundu (M-W-U=15.000, p
Keywords
References
- Lawrence WT, Potenza MS. Tissue transfer: fat, dermal, mus- cle, cartilage and fascial grafts. In: Cohen M, Goldwyn RM edi- tor. Mastery of Plastic and Reconstructive Surgery. Vol. 1. London: Little, Brown and Company; 1994. p .88-94.
- Brent, B. Repair and grafting of cartilage and perichondrium. In: McCarthy, JG, editor. Plastic surgery. Philadelphia: W. B. Saunders Co.; 1990. p. 559-80.
- Silver FH, Glasgold AI. Cartilage wound healing. An overview. Otolaryngol Clin North Am 1995;28:847-64.
- Gherardini G, Bathia N, Stal S. Costal cartilage grafts. In: Evans GRD, editor. Operative plastic surgery. New York: Mc Graw- Hill Company; 2000. p. 76-89.
- Özbek S, Şen C, Kahveci Z, Özcan M. The effect of heterolo- gous collagen in neochondrogenesis from free perichondrial grafts, in rabbits: an experimental study. [Article in Turkish] Ulus Travma Acil Cerrahi Derg 2003;9:17-22.
- Duynstee MLG, Verwoed-Verhoef HL, Verwoed CDA, et al. The Dual role of perichondrium in cartilage wound healing. Plast Reconstr Surg 2002;110:1073-9.
- Lester CW. Tissue replacement after subperichondrial resection of costal cartilage: two case reports. Plast Reconstr Surg Transplant Bull 1959;23:49-54.
- Skoog T, Johansson SH. The formation of articuler cartilage from free perichondrial grafts. Plast Reconstr Surg 1976;57:1-6.
- Bruns J, Kertsen P, Lierse W, Weiss A, Silbermann M. The in vitro influence of different culture conditions on the potential of sheep rib perichondrium to form hyaline-like cartilage. Evaluation of gluing materials used for in vivo graft fixation. Wirchows Archiv 1994;424:169-75.
- Silverstein LH, Kraft JD, Wand R. Bone regeneration and tissue acceptance of human fascia lata grafts adjacent to dental implants: a preliminarycase report. J Oral Implantol 1992;18: 394-8.
- Krol R, Barcew-Wiszniewska B. Morphological evaluation of fascia lata tissue implantation for chondral defects in the knee joint of sheep under active motion and load. [Article in Polish] Chir Narzadow Ruchu Ortop Pol 1991;56:129-33.
- Bruno de Rezende Pinna, João Norberto Stavale, Paulo Augusto de Lima Pontes, Osíris de Oliveira Camponês do Brasil. Histological analysis of autologous fascia graft implantation into the rabbit voice muscle. Braz J Otorhinolaryngol 2011;77:185-90.
- Yildirim G, Onar V, Sayin I, Onol SD, Aydin T. The recon- struction of nasal septal perforation with high density porous polyethylene covered with fascia lata: an experimental study on rabbit model. Clin Exp Otorhinolaryngol 2011;4:137-41.
- Hosokawa K, Hata Y, Yano K, Matsuka K, Ito O. Inhibitory effect of mature cartilage on perichondrial neochondrogenesis. Ann Plast Surg 1989;23:155-8.
- Ito Y, Fitzsimmons JS, Sanyal A, Mello MA, Mukherjee N, O’Driscoll SW. Localization of chondrocyte precursors in periosteum. Osteoarthritis Cartilage 2001;9:215-23.
- Hosokawa K, Hata Y, Yano K, Matsuka K. Cartilage formation from perichondrium in a difusion chamber. Ann Plast Surg 1988;21:140-2.
- Lopez Aguado D, Monserrat JR, Perez Piñero B, Campos Bañales ME, Gutierrez R, Diaz Flores L. Neochondrogenesis in the septal area after submucous cartilaginous resection. Acta Otolaryngol 1992;112:539-44.
- Robenson D, Nevo Z. Articuler cartilage chondrocytes are more advantageous for regenerating hyaline-like cartilage than mes- enchymal cells isolated from microfracture repairs. Cell Tissue Bank 2001;2:23-30.
- Caplan AI, Elyaderani M, Mochizuki Y, Wakitani S, Goldberg VM. Principles of cartilage repair and regeneration. Clin Orthop Relat Res 1997;(342):254-69.
- Thammavaram KV1, Benzel EC, Kesterson L. Fascia lata graft as a dural substitute in neurosurgery. South Med J 1990;83:634-6.
- Fitzgerald MP, Mollenhauer J, Brubaker L. The antigenicity of fascia lata allografts. BJU Int 2000;86:826-8.
- Ghoniem GM. Allograft sling material: is it the state of the art? Int Urogynecol J Pelvic Floor Dysfunct 2000;11:69-70.
- This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY
- NC-ND0) Licence (http://creativecommons.org/licenses/by-nc-nd/3.0/) which permits unrestricted noncommercial use, distribution, and reproduc
- tion in any medium, provided the original work is properly cited.
- Please cite this article as: Yılmaz Ş, Bilkay Ö, Özdemir ‹, Avcı A, Adadan Güvenç I. Investigation of the effects of fascia lata on neochondrogenesis in
- a rabbit model. J Med Updates 2014;4(2):66-70.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | June 1, 2014 |
| Published in Issue | Year 2014 Volume: 4 Issue: 2 |