Evaluation of olfactory function in migraineurs during the migraine-free period with odor identification test

Year 2014, Volume: 4 Issue: 1, 1 - 5, 01.03.2014

Hakan Tekeli Mehmet Güney Şenol Fatih Özdağ Mehmet Saraçoğlu Halit Yaşar Mustafa Tansel Kendirli Aytuğ Altundağ Melih Çayönü Murat Salihoğlu Türker Türker

https://doi.org/10.2399/jmu.2014001001

Abstract

Objective: Despite the fact that there are many studies about the osmophobia and migraine, we have very little knowledge about the olfactory abilities of migraineurs during the period between the attacks. So, the aim of this study was to evaluate the olfactory function of migraineurs during the period without headaches with odor identification test. Methods: Two hundred and ninety healthy people aged 16 to 65 years (152 female, 138 male) and 84 migraine patients aged 18 to 55 years (47 female, 37 male) were studied. The participants with migraine were selected from the patients who applied to headache outpatient clinic for assessment. Participants, appropriate to the study, were physically and neurologically examined in detail and then they were taken to the test room in order to be screened with Short Smell Test Battery of GATA Haydarpaşa (GULTEST). Results: The mean GULTEST score of the migraine group was less than the healthy group and the difference was significant. The effect of gender, cigarette smoking and disease status (migraine) on GULTEST scores was evaluated by linear regression model. It was found that females had higher odor identification scores than males in both migraineurs and controls. On the other hand, cigarette smoking had a significant negative effect on GULTEST scores. Furthermore, migraine had a significant negative effect on GULTEST scores. Conclusion: Our study showed that even during the headache-free period, migraineurs might have reduced olfactory abilities.

Keywords

Migraine, smell, olfaction disorders, headache

Migren hastalarında atak olmayan dönemde koku tanımlama testi ile koku fonksiyonunun değerlendirilmesi

Abstract

Amaç: Osmophobia ve migren konusunda birçok çalışmanın varlığına rağmen, migren hastalarının ataklar arası dönemde koku alma yetenekleri hakkında çok az bilgiye sahibiz. Bu nedenle bu çalışmanın amacı migren hastalarının başağrısı olmayan dönemde koku tanımlama testi ile koku alma fonksiyonlarının değerlendirilmesidir. Yöntem: Yaşları 16-65 arasında olan 290 sağlıklı birey (152 kadın, 138 erkek) ve yaşları 18-55 arasında olan 84 migren hastası (47 kadın, 37 erkek) çalışmaya dahil edildi. Migreni olan katılımcılar değerlendirilmek üzere başağrısı polikliniğine başvuran hastalardan seçildi. Çalışmaya uygun olan katılımcılar nörolojik ve fiziksel olarak detaylı bir şekilde değerlendirildi ve daha sonra GATA Haydarpaşa Kısa Koku Test Bataryası (GULTEST) ile değerlendirme yapılması için test odasına alındı. Bulgular: Migren grubunun ortalama GULTEST skoru sağlıklı gruba göre daha az idi ve fark anlamlıydı. GULTEST skorlarına cinsiyetin, sigara içmenin ve hastalık durumunun (migren) etkisi lineer regresyon modeli ile değerlendirildi. Hem migren hastalarında hem de sağlıklı kontrollerde kadınların erkeklere göre daha yüksek koku tanımla skorları aldıkları saptandı. Buna karşılık, sigara içmenin GULTEST skorları üzerinde anlamlı bir olumsuz etkisi vardı. Ayrıca, migrenin de GULTEST skorları üzerinde anlamlı bir olumsuz etkisi vardı. Sonuç: Araştırmamız migren hastalarında başağrısı olmadığı dönemlerde dahi koku alma yeteneklerinin azalmış olabileceğini göstermiştir.

Keywords

Migren, koku, koku alma bozuklukları, başağrısı

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• Please cite this article as: Tekeli H, Şenol MG, Özda¤ F, Saraço¤lu M, Yaflar H, Kendirli MT, Altunda¤ A, Çayönü M, Saliho¤lu M, Türker T.
• Evaluation of olfactory function in migraineurs during the migraine-free period with odor identification test. J Med Updates 2014;4(1):1-5.