Oncologic Outcomes of Endoscopic Resection for Early Gastric Cancer

Year 2017, Volume: 3 Issue: 1, 8 - 15, 30.03.2017

Cemil Bilir Hakan Cinemre

Abstract

Gastric
cancer is the fifth most common cancer in the world, and about one million new
cases develop globally each year. Early Gastric Cancer (EGC) is a stage that
tumor invades gastric mucosa or submucosa with or without involvement of the
lymph nodes (LN). Endoscopic resection techniques
are endoscopic mucosal resection (EMR) and endoscopic submucosal dissection
(ESD), latter of which is more popular now. Gastrectomy is the standard choice
of treatment but, is highly invasive that requires longer stay at hospital, with
higher costs and complication rates, especially at the anastomotic site. EMR was
used more frequently before the development of ESD but, now give its popularity
to ESD and EMR depends on the region and experience of the center. EMR is more
convenient method for smaller lesions, associated with lower bleeding risk and
shorter duration of operation compared to ESD. On the other hand, ESD has lower
en-block resection rates and recurrence rates compared to EMR. In this review,
we analyzed over than 10.000 patients’ oncologic outcomes including overall
survival, disease free survival and recurrence rates.  In conclusion, many newly diagnosed gastric cancer
patients are seeking micro-invasive treatment modalities around the World for
their early stage cancers. Endoscopic submucosal resection and endoscopic
mucosal resection are safe and convenient procedures and had comparable
oncologic outcomes with surgery. Additionally, these techniques can easily be
used in patients who are not surgical candidates. 

Keywords

Early gastric cancer, endoscopic resection

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