ABSTRACT
Background: Aim of this study is to determine the impact of atrial septal aneurysm on atrial
electrophysiology in pregnancy by the investigation of P-wave duration and
P-wave dispersion on electrocardiography.
Method: This study
includes 98 pregnant
women, divided in two groups according to presence
of atrial septal aneurysm (ASA) (n=48 ASA
positive group, n=50 ASA negative group). P-wave
dispersion was calculated by using the 12-lead electrocardiogram with a speed of
50 mm/sec for each participant. Cardiac functions and morphology of the aneurysm were
measured using conventional echocardiography. ASA was defined if the excursion of the septum primum
into the left/right atriums exceeded 10 mm or the total excursion distance was
more than 15 mm.
Results: Demographic
and clinical findings were similar between ASA positive group and ASA negative
group, there was no significant difference. Compared to the ASA
negative group, pregnant women with ASA showed significantly longer maximum P
wave dispersion (PWD) (54.10±12.42 ms vs. 37,42±14,27 ms , p = 0.0001). Similarly,
the maximum duration of the P wave (Pmax) in the ASA
positive group was significantly longer than the ASA negative group (118,35±11,41 ms vs.
110,54±9,452 ms , p=0,0004). P wave
dispersion and Pmax were not correlated with
age, gravida, parity, gestational week, body mass
index or M mode Echocardiographic parameters.
Discussion: In this study, it was shown
that P-wave dispersion is prolonged in pregnant women with atrial septal
aneurysm. PWD may be a pre-determinative for atrial structural
anomalies or atrial arrhythmias in pregnancy and this non invasive method
should be used to predict cardiac risk at the beginning of pregnancy.
Primary Language | English |
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Subjects | Health Care Administration |
Journal Section | Articles |
Authors | |
Publication Date | September 1, 2019 |
Submission Date | April 24, 2019 |
Acceptance Date | August 9, 2019 |
Published in Issue | Year 2019 Volume: 5 Issue: 3 |