Ethnomedicinal Uses, Phytochemistry and Pharmacology of Few Species of Genus Atalantia (Rutaceae): A Review

Year 2023, Volume: 10 Issue: 3, 805 - 820, 30.08.2023

Pournima Shelar , Santosh Kumar Sıngh

https://doi.org/10.18596/jotcsa.1252184

Abstract

Synthetic drugs show major side effects, as well as the fact that they have been discovered to be extremely harmful to human assistance, many synthetic medications claimed to be used for treatment are of the least interest today. Therefore, herbal medicines have acquired prominence in recent decades. This review's primary objective is to give a complete overview of three distinct species of the Genus Atalantia mainly Atalantia monophylla (Roxb) DC, Atalantia racemaosa Wight, Atalantia wightii Tanaka. The Genus Atalantia belongs to Rutaceae family and there are 22 accepted species of which three species are selected because these are available in Western Ghat region of Maharashtra, these species have ethnopharmacological significance and many of their facets are still unexplored. The Atalantia genus is utilized in conventional medicine to treat a diverse array of ailments like fever, rheumatic pains, cough, allergy, swelling, and as a blood purifier, etc. The current work is a comprehensive analysis of the published literature on phytochemical and pharmacological reports of the above species of Atalantia genus in an effort to deliver comprehensive information and suggest future research avenues. Out of these three species, Atalantia monophylla has received the most research attention but the remaining two species are not much explored. The aim of this review is to discuss the potential application of these three species as herbal medicine. The plant characteristics, ethnobotanical uses, phytochemistry, and pharmacological activities are summarized as a guide for phytochemical and pharmacological investigations.

Keywords

Genus Atalanta, Traditional uses, Morphology, Phytochemistry, Pharmacology

Thanks

I am thankful to Suresh Gyan Vihar School of Pharmacy, Jaipur, Rajasthan for providing all the necessary requirements.

References

• 1. Nigussie G. A review on traditionally used medicinal plants for scabies therapy in Ethiopia. ADV TRADIT MED (ADTM). 2021 Jun; 21(2):199– 208. Available from: <URL>
• 2. Swingle WT. “The Botany of Citrus and its Wild Relatives in the Citrus Industry,” University of California Press, Berkely. 1967; 190-430.
• 3. Das AK, Swamy PS. Antioxidant activity and determination of bioactive compounds by GC-MS in methanolic fruit extract -a comparative analysis of three Atalantia species from south India. Journal of Applied Pharmaceutical Science. 2016; 6 (02): 130-134. Available from: <URL>
• 4. Khare CP. Indian Medicinal Plants; An Illustrated Dictionary. New York. Springer. 2007.
• 5. Ezekiel Amri, Daniel PK. Ethnomedicinal study of plants used in villages around Kimboza forest reserve in Morogoro, Tanzania. Journal of Ethnobiology and Ethnomedicine. 2012; 8 (1): 1-9. Available from: <URL>
• 6. Carl WC. Indian Atalantia, An ornamental tree for landscaping in southern florida. Process Florida State Horticulture Society. 1979; 92:215.
• 7. Pullaiah T. Encyclopaedia of World Medicinal Plants. Volume 1. Daya books publisher. New Delhi: Regency. 2006.
• 8. Parthasarathy N, Karthikeyan R. Plant biodiversity inventory and conservation of two tropical dry evergreen forests on the Coromandel coast, south India. Biodiversity and conservation. 1997;6: 1063-1083. Available from: <URL>
• 9. Parthasarathy N, Selwyn M, Udaykumar M. 2008. Tropical dry evergreen forests of peninsular India; ecology and conservation significance. Tropical Conservation Science. 1(2): 89-110. Available from: <URL>
• 10. Venkateswaran R, Parthasarathy N. Tree population changes in a tropical dry evergreen forest of south India over a decade (1992–2002). Biodiversity and conservation. 2005;14: 1335-1344. Available from: <URL>
• 11. Panda H. Handbook on Medicinal Herbs with uses. India; Asia Pacific Business Press Inc. 2004.
• 12. Radhakrishnan M, Jindal A, Baldev G, Bhatt S, Pandey D. Evaluation of anti-diabetic activity of methanolic extract from the bark of Atalantia monophylla (Linn.) in alloxan-induced diabetic mice. International Journal of Green Pharmacy. 2012; 6(2):133-137. Available from: <URL>
• 13. Shrikant G, Rajeshwari N, Vasudeva R, Ganeshaiah KN. Floristic composition of the kaan forests of Sagar Taluk: sacred landscape in the central Western Ghats, Karnataka, India. Journal of Biodiversity Data. 2015; 11(3): 1626. Available from: <URL>
• 14. Bharath Kumar R, Suryanarayana B. Ethnomedicinal recipes for respiratory and bronchial diseases from Tribals of Sriharikota Island, Andhra Pradesh. Journal of Ethnobotanical Leaflet. 2008;12: 896–911. Available from: <URL>
• 15. Kottaimuthu P, Vasudevan N. Traditional Medicine among the Palliyars of Palani Hills, Western Ghats, India. International Journal of Arts, Science and Humanities. 2021; 8 (1): 10-14. Available from: <URL>
• 16. Lalbiakngheti T, Lucy L. Commonly used medicinal plants in N. Mualcheng, Mizoram, India. Science Vision. 2020; 20(4): 156–161. Available from: <URL>
• 17. Rekka R, Nirubama K, Suganya B, Rubavathigokila M. Sacred groves–an ancient tradition of nature conservation of sthalavrikshas in coimbatore, Tamil nadu, India. Kongunadu Research Journal. 2021; 8(2):1-7. Available from: <URL>
• 18. David RS, Alina AM, Jesse TJ, Beena R, Agnes H. Herbs as Antidote for Snake Bite Treatment- Traditional Practices and Its Future Prospects- A Review. Journal of Natural Remedies. 2022; 22(3): 269-290. Available from: <URL>
• 19. Rajkumar P, Natranjan S, Bhasha M, Ismailkhan A. Floristic and medicinal plant survey at Karaivetti bird sanctuary, Tamil Nadu, India, Spatula DD. 2015; 5 (1):27–34. Available from: <URL> 20. Prabakaran RT, Senthil T, Rao M. Role of non-timber forest products in the livelihood of Malayali tribe of Chitteri hills of southern eastern Ghats, Tamil Nadu India. Journal of Applied Pharmaceutical Science. 2013; 3 (5): 56–60. Available from: <URL>
• 21. Senthil Kumar R, Moorthy K, Raja V, Punitha T. Antimicrobial efficacy and phytochemical analysis of Indigofera Trita Linn. African Journal of Traditional, Complementary and Alternative Medicine. 2013; 10 (3): 518–525. Available from: <URL>
• 22. Rastogi R, Mehrotra B. Compendium of Indian Medicinal Plants, Central Drug Research Institute; Publications & Information Directorate, New Delhi. 1990; (2): 1970–1979.
• 23. Maurya DK, Nandkumar N, Paul T. Anticancer property of gallic acid in A-549, a human lung adenocarcinoma cell line, and possible mechanisms. Journal of Clinical Biochemistry and Nutrition. 2011; 48 (1): 85–90. Available from: <URL>
• 24. Dreyer DL, Bennett RD, Basa SC. Limonoids from Atalantia monophylla isolation and structure. Tetrahedron. 1976; 32: 2367–2373. Available from: <URL>
• 25. Yogeshwari C, Kumudha P. Ethnobotany of Sholaga tribes of Kathri hills, Chennampatti Range, Western Ghats, India. Research Journal of Pharmacognosy and Phytochemistry. 2018: 10 (2): 179-182. Available from: <URL>
• 26. Chellaiah M, Kathirvelu B, Selvadurai K, Savarimuthu I. Bioefficacy of Atalantia monophylla (l.) correa. against Earias vittella fab. Journal of Central European Agriculture. 2010; 11: 27-30. Available from: <URL> 27. Sanath Kumar, Krupadanam D, Akshay Kumar K. A new alkaloid 5-Hydroxydictamnine from Atalantia monophylla. Natural Product Research. 2010; 24(16), 1514–1517. Available from: <URL>
• 28. Kathirvelu B, Chellaih M, Gnanaprakasam A, Selvadurai K, Savarimuthu I. Ovicidal activity of Atalantia monophylla (L) Correa against Spodoptera litura Fab. (Lepidoptera: Noctuidae). Asian pacific journal of tropical biomedicine. 2012; 2(12): 987-991. Available from: <URL>
• 29. Pandian P. Pharmacognostic, physicochemical and phytochemical investigation of Atalantia monophylla (l.) Correa leaves. Rapports De Pharmacie. 2015; 1 (3): 152-160.
• 30. Kathirvelu B, Chellaih M, Savarimuthu I. Bio Efficacy of Atalantia monophylla (L) Correa (Rutaceae) against Spodoptera litura Fabricius (Lepidoptera: Noctuidae). Entomology, Ornithology & Herpetology: Current research. 2015; 4(2): 1-5. Available from: <URL>
• 31. Patil VR, Thakare V, Joshi V. Immunomodulatory Activity of Atalantia monophylla DC. Roots. Pharmacognosy Journal. 2015; 7(1): 37-41. Available from: <URL>
• 32. Thirugnanasampandan R, Gunasekar R, Gogulramnath M. Antioxidant and antibacterial activity evaluation, Chemical composition analysis of essential oil of Atalantia monophylla Correa. Pharmacognosy Research. 2015; 7(1): S52-S56. Available from: <URL>
• 33. Pandian P, Selvamuthukumar S. Evaluation of in vitro antioxidant activity of ethanolic extracts from Atalantia monophylla leaves. Journal of Pharmaceutical Sciences & Research. 2016; 8(12): 1378-1383.
• 34. Thirugnanasampandan R, Gunasekar R, Gogulramnath M. Antigenotoxic and apoptotic activities of essential oil of Atalantia monophylla Correa. Indian Journal of Pharmacology. 2016; 48(6): 720-724. Available from: <URL>
• 35. Nattudurai G, Kathirvelu B, Pulraj M, Islam V. Toxic effect of Atalantia monophylla essential oil on Callosobruchus maculatus and Sitophilus oryzae. Environmental Science and Pollution Research. 2016; 24(2):1619-1629. Available from: <URL>
• 36. Sujatha S, Seker T, Pavithra S. Free-radical scavenging activity of stem and leaf of Atalantia monophylla (L.) Corr. Serr. International Journal of Herbal Medicine. 2017; 5(4): 47-53. Available from: <URL>
• 37. Premalatha S, Karthi A. Phytochemical screening and antimicrobial activity of leaf of Atalantia monophylla (l.) Corr (Rutaceae). International Journal of Pharmacy and Biological Sciences. 2017; 7(4):179-184. Available from: <URL>
• 38. Posri P, Suthiwong J, Takomthong P, Wongsa C. A new flavonoid from the leaves of Atalantia monophylla (L.) DC. Natural Product Research. 2018; 33(8): 1115-1121. Available from: <URL>
• 39. Subramaniyan V. Mahadevan S, Arulmozhi P, Subramanian S. Green synthesis of zinc oxide nanoparticles using Atalantia monophylla leaf extracts: Characterization and antimicrobial analysis. Materials Science in Semiconductor Processing. 2018; 82; 39-45. Available from: <URL>
• 40 Aonnicha Sombatsri. 2018. New limonophyllines A-C from the stem of Atalantia monophylla and cytotoxicity against cholangiocarcinoma and HepG2 cell lines. Archives of Pharmacal Research. 41(4):431-437. Available from: <URL>
• 41. Premalatha S, Ramar G. Anti-bacterial properties of fractions isolated from Couroupita guianensis and Atalantia monophylla. The Pharma Innovation Journal. 2019; 8(1): 542-547. Available from: <URL>
• 42. Thurdpong S, Yutthapong T, Suphantip P, Veerapol K, Sarawut T. Isolated styrenes from the Seeds of Atalantia monophylla. Journal of Natural Product. 2019; 82(8): 2246–2251. Available from: <URL>
• 43. Naga Padmavathi V, Chetty KM. Morpho-Anatomical studies of Atalantia racemosa Wight ex Hook., an important medicinal plant of Chittoor Dt. of Andhra Pradesh, India. International Journal of Bio-Pharma Research. 2019; 8(2): 2491-2499. Available from: <URL>
• 44. Harsha VH, Hebbar SS, Shripathi V. Ethnomedicobotany of Uttara Kannada District in Karnataka, India—plants in treatment of skin diseases. Journal of Ethnopharmacology. 2003; 84(1): 37-40. Available from: <URL>
• 45. Devi Prasad AG, Shyma TB, Raghavendra MP. Plants used by the tribes for the treatment of digestive system disorders in Wayanad district, Kerala. Journal of Applied Pharmaceutical Science. 2013; 3(8):171-175. Available from: <URL>
• 46. Sathiyaraj R, Sarvalingam A, Arulbalachandran, Rama KR. Diversity of Ethnomedicinal Plants in Bodamalai Hills Eastern Ghats, Namakkal District, Tamil Nadu. Journal of Plant Sciences. 2015; 3(2): 77-84. Available from: <URL>
• 47. Das AK, Swamy PS. Comparison of the volatile oil composition of three Atalantia species. Journal of Environmental Biology. 2013; 34: 569-571. Available from: <URL>
• 48. Das AK, Suresh Kumar J, Swamy PS. Larvicidal activity and leaf essential oil composition of three species of genus Atalantia from south India. International Journal of Mosquito Research. 2015; 2(3): 25-29. Available from: <URL>
• 49. Arumugam P, Saraswathi K. Mahakashmi B, Rajesh V. 2017. Invitro evaluation of the antioxidant and antimicrobial potential of leaves of Atalantia racemosa Wight ex Hook. International Journal of Pharma Research and Health Sciences. 5 (6): 2031-37. Available from: <URL>
• 50. Kokkaiah I, Sethupandian G, Palanichamy M. Antimicrobial activity of selected indian folk medicinal plants: Myristica fatua, Alstonia boonei, Helictere sisora, Vitex altissima, and Atalantia racemosa. Asian Journal of Pharmaceutical and Clinical Research. 2017; 10 (2): 277-280. Available from: <URL>
• 51. Kokkaiah I, Vadivel S. Qualitative phytochemical constituents assay of diverse solvent extracts of chosen medicinal plants. International Journal of Green and Herbal Chemistry. 2018; 7(4): 741-748. Available from: <URL>
• 52. Adhav Rahul, Deokule S. Evaluation of antioxidant, α-glucosidase and α-amylase inhibitory activities of Atalantia racemosa and Senna uniflora leaves. Asian Journal of Pharmaceutical and Clinical Research. 2018; 11(5): 254-258. Available from: <URL>
• 53. Parthipan G, Shanthi K. Phytochemical studies and antibacterial activities on Atlantia racemosa Wight & Arn. International Journal of Green and Herbal Chemistry. 2019; 8(4): 446-451. Available from: <URL>
• 54. Parthipan G, Shanthi K. Leaf anatomical studies of Atalantia racemosa wight Ex Hook, an important medicinal plant of Tiruvannamalai, Tamilnadu, India. International journal of current research. 2020; 12 (2): 10303-10308. Available from: <URL>
• 55. Ganer R, Kamble MA. Evaluation of Analgesic and In-vitro Anti-Inflammatory Potential of Fruit Flesh Extract of Terminalia catappa Linn. Research Journal of Pharmacognosy and Phytochemistry. 2017; 9(4): 228-230. Available from: <URL>
• 56. Matthew KM. The Flora of Palni Hills, The Rapinat herbarium, St. Joseph’s College, Tiruchirappalli, 1999; 178-191.
• 57. Ayyanar M. Traditional Herbal Medicines for Primary Healthcare among Indigenous People in Tamil Nadu, India. Journal of Homeopathy & Ayurvedic Medicine. 2013; 2(5): 1-7. Available from: <URL>
• 58. Govindchari TR. Chemical and Biological Investigations on Indian Medicinal Plants. Indian New Natural Products and Plant Drugs with Pharmacological, Biological or Therapeutical Activity. 1976; 212-226. Available from: <URL>
• 59. Sethuraman MG, Ramesh V, Gopan R, Anil J, George V. Chemical Composition of the Leaf, Stem and Root Oils of Pleiospermium alatum. Journal of Essential Oil Research. 2011; 23(6):1-4. Available from: <URL>