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Telositlerin Morfolojisi ve Fonksiyonları

Year 2020, Volume: 10 Issue: 2, 161 - 170, 01.08.2020

Özlem Delibaş , Serpil Ünver Saraydın

Abstract

Birçok organ ve dokunun stromasında ortaya çıkan bir hücre popülasyonu olan telositler, telopod olarak adlandırılan değişken sayıda çok uzun ince sitoplazmik uzantılarıyla ve göze çarpmayan küçük hücre gövdeleri ile karakterizedir. Bu hücreleri belirlemek için immünohistokimsayasal boyama teknikleri ve elektron mikroskop yöntemleri kullanılmıştır. Telopodlar, telositlerin homo- veya hetero-hücresel temaslar oluşturmasına yardımcı olur, böylece organların stromal ve parankimal bileşenlerini düzenleyen üç boyutlu ağlar oluşturur. Telositler, kısa mesafeli bir iletişim sağlayarak komşu hücrelere bilgi aktarabilir ve eksozomlar, ektozomlar ve multiveziküler kargolar gibi çeşitli hücre dışı vezikülleri ile hücre içi sinyal iletişimine karışmaktadır. Bu derlemede telositlerin morfolojik özelikleri, farklı organlarda ve dokulardaki dağılımlarına, fonksiyonlarına ve moleküler belirteçlerine değinilmiştir.

Keywords

telosit telopod podom podomer

References

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  • 2. Faussone-Pellegrini MS. Ultrastructure of the tunica muscularis of the cardial portion of the human esophagus and stomach, with special reference to the so-called Cajal’s interstitial cells. Arch Ital Anat Embryol 1977;82(2):157–77.
  • 3. Thuneberg L. Interstitial cells of Cajal: intestinal pacemaker cells? Adv Anat Embryol Cell Biol 1982;71:1–130.
  • 4. Gabella G. Intestinal smooth muscle development. In Advances in the Innervation of the Gastrointestinal Tract. Elsevier Science Publishers; 1992. p.35–47.
  • 5. Torihashi S, Gerthoffer WT, Kobayashi S, Sanders KM. Identification and classification of interstitial cells in the canine proximal colon by ultrastructure and immunocytochemistry. Histochemistry 1994;101(3):169–83.
  • 6. Sanders KM, Koh SD, Ward SM. Interstitial cells of Cajal as pacemakers in the gastrointestinal tract. Annu Rev Physiol 2006;68:307–43.
  • 7. Forrest A, Huizinga JD, Wang XY, Liu LW, Parsons M. Increase in stretch-induced rhythmic motor activity in the diabetic rat colon is associated with loss of ICC of the submuscular plexus. Am J Physiol Gastrointest Liver Physiol 2008;294(1): G315–26.
  • 8. Lecoin L, Gabella G, Le Douarin N. Origin of the c-kitpositive interstitial cells in the avian bowel. Development 1996;122(3):725–33.
  • 9. Popescu LM, Hinescu M E, Ionescu N, Ciontea SM, Cretoiu D, Ardelean C. Interstitial cells of Cajal in pancreas. J Cell Mol Med 2005;9(1):169–90.
  • 10. Ciontea SM, Radu E, Regalia T, Ceafalan L, CretoiuD, Gherghiceanu M, et al. C-kit immunopositive interstitial cells (Cajal-type) in human myometrium. J Cell Mol Med 2005;9(2):407–20.
  • 11. Hutchings G, Williams O, Cretoiu D, Ciontea SM. Myometrial interstitial cells and the coordination of myometrial contractility. J Cell Mol Med 2009;13(10):4268–82.
  • 12. Popescu LM, Faussone-Pellegrini MS. TELOCYTES - a case of serendipity: the winding way from Interstitial Cells of Cajal (ICC), via Interstitial Cajal-Like Cells (ICLC) to TELOCYTES. J Cell Mol Med 2010;14(4):729–40.
  • 13. Popescu LM, Gherghiceanu M, Suciu LC, Manole CG, Hinescu ME. Telocytes and putative stem cells in the lungs: electron microscopy, electron tomography and laser scanning microscopy. Cell Tissue Res 2011;345(3):391–403.
  • 14. Cretoiu D, Cretoiu SM, Simionescu AA, Popescu LM. Telocytes, a distinct type of cell among the stromal cells present in the lamina propria of jejunum. Histol Histopathol 2012;27(8):1067–78.
  • 15. Cretoiu D. The Third Dimension of Telocytes Revealed by FIBSEM Tomography. In: Telocytes. Adv Exp Med Biol (Singapore) 2016;913:325–34.
  • 16. Faussone-Pellegrini MS, Gherghiceanu M. Telocyte’s contacts. Semin Cell Dev Biol 2016;55:3–8.
  • 17. Bassotti G, Villanacci V, Cretoiu D, Cretoiu SM, Becheanu G. Cellular and molecular basis of chronic constipation: taking the functional/idiopathic label out. World J Gastroenterol 2013;19(26):4099–105.
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  • 19. Popescu LM, Gherghiceanu M, Manole CG. FaussonePellegrini MS. Cardiac renewing: interstitial Cajal-like cells nurse cardiomyocyte progenitors in epicardial stem cell niches. J Cell Mol Med 2009;13(5):866–86.
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  • 21. Luesma MJ, Gherghiceanu M, Popescu LM. Telocytes andstem cells in limbus and uvea of mouse eye. J Cell Mol Med 2013;17(8):1016–24.
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  • 26. Song D, Cretoiu D, Zheng M, Qian M, Zhang M, Cretoiu SM, et al. Comparison of Chromosome 4 gene expression profile between lung telocytes and other local cell types. J Cell Mol Med 2016;20(1):71–80.
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  • 28. Cretoiu D, Vannucchi MG, Bei Y, Manetti M, FaussonePellegrini MS, Ibba-Manneschi L, et al. Telocytes: New Connecting Devices in the Stromal Space of Organs. In: Loewy Z, editor. Innovations in Cell Research and Therapy. London, UK: IntechOpen; 2019.
  • 29. Kucybala I, Janas P, Ciuk S, Cholopiak W, Klimek-Piotrowska W, Holda MK. A comprehensive guide to telocytes and their great potential in cardiovascular system. Bratislavske Lekarske Listy 2017;118(5):302–9.
  • 30. Popescu LM. The tandem: Telocytes-Stem cells. J Biol Biomed Eng 2011;5(2):83–92.
  • 31. Popescu LM, Ciontea SM, Cretoiu D. Interstitial Cajal-like cells in human uterus and fallopian tube. Ann N Y Acad Sci 2007;1101(1):139–65.
  • 32. Cretoiu D, Xu J, Xiao J, Cretoiu SM. Telocytes and their extracellular vesicles-Evidence and Hypotheses. Int J Mol Sci 2016;17(8):1322.
  • 33. Popescu LM, Manole CG, Gherghiceanu M, Ardelean A, Nicolescu MI, Hinescu ME, et al. Telocytes in human epicardium. J Cell Mol Med 2010;14(8):2085–93.
  • 34. Kostin S. Myocardial telocytes: a specific new cellular entity. J Cell Mol Med 2010;14(7):1917–21.
  • 35. Hinescu ME, Popescu LM. Interstitial Cajal-like cells (ICLC) in human atrial myocardium. J Cell Mol Med 2005;9(4):972–5.
  • 36. Cretoiu SM, Cretoiu D, Popescu LM. Human myometriumthe ultrastructural 3D network of telocytes. J Cell Mol Med 2012;16(11):2844–9.
  • 37. Vannucchi MG, Traini C, Manetti M, Ibba-Manneschi L, Faussone Pellegrini MS. Telocytes express PDGFRα in the human gastrointestinal tract. J Cell Mol Med 2013;17(9):1099–108.
  • 38. Corradi LS, Jesus MM, Fochi RA, Vilamaior PS, Justulin LA, Jr Góes RM, et al. Structural and ultrastructural evidence for telocytes in prostate stroma. J Cell Mol Med 2013;17(3):398–406.
  • 39. Hinescu ME, Gherghiceanu M, Mandache E, Ciontea SM, Popescu LM. Interstitial Cajal-like cells (ICLC) in atrial myocardium: ultrastructural and immunohistochemical characterization. J Cell Mol Med 2006;10(1):243–57.
  • 40. Shah S, Lubeck E, Zhou W, Cai L. seqFISH Accurately Detects Transcripts in Single Cells and Reveals Robust Spatial Organization in the Hippocampus. Neuron 2017;94(4):752–8.
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  • 42. Bani D, Formigli L, Gherghiceanu M, Faussone-Pellegrini MS. Telocytes as supporting cells for myocardial tissue organization in developing and adult heart. J Cell Mol Med 2010;14(10):2531–8.
  • 43. Ceafalan L, Gherghiceanu M, Popescu LM, Simionescu O. Telocytes in human skin-are they involved in skin regeneration? J Cell Mol Med 2012;16(7):1405–20.
  • 44. Vannucchi MG, Traini C, Guasti D, Del Popolo G, FaussonePellegrini MS. Telocytes subtypes in human urinary bladder. J Cell Mol Med 2014;18(10):2000–8.
  • 45. Pieri L, Vannucchi MG, Faussone-Pellegrini MS. Histochemical and ultrastructural characteristics of an interstitial cell type different from ICC and resident in the muscle coat of human gut. J Cell Mol Med 2008;12(5b):1944–55.
  • 46. Dìaz-Flores L, Gutierrez R, Sáez FJ, Dìaz-Flores Jr L, Madrid JF. Telocytes in neuromuscular spindles. J Cell Mol Med 2013;17(4):457–65.
  • 47. Chaitow L. Telocytes: Connective tissue repair and communication cells. J Bodywork Mov Ther 2017;21(2):231–3.
  • 48. Gherghiceanu M, Popescu LM. Cardiac telocytes - their junctions and functional implications. Cell Tissue Res 2012;348(2):265–79.
  • 49. Fertig ET, Gherghiceanu M, Popescu LM. Extracellular vesicles release by cardiac telocytes: electron microscopy and electron tomography. J Cell Mol Med 2014;18(10):1938–43.
  • 50. Zhou J, Zhang Y, Wen X, Cao J, Li D, Lin Q, et al. Telocytes accompanying cardiomyocyte in primary culture: two- and threedimensional culture environment. J Cell Mol Med 2010;14(11):2641–5.
  • 51. Albulescu R, Tanase C, Codrici E, Popescu D, Cretoiu SM, Popescu LM. The secretome of myocardial telocytes modulates the activity of cardiac stem cells. J Cell Mol Med 2015;19(8):1783–94.
  • 52. Kang Y, Zhu Z, Zheng Y, Wan W, Manole CG, Zhang Q. Skin telocytes versus fibroblasts: two distinct dermal cell populations. J Cell Mol Med 2015;19(11):2530–9.
  • 53. Popescu LM, Manole E, Şerboiu CS, Manole CG, Suciu LC, Gherghiceanu M, et al. Identification of telocytes in skeletal muscle interstitium: implication for muscle regeneration. J Cell Mol Med 2011;15(6):1379–92.
  • 54. Yang Y, Sun W, Wu SM, Xiao J, Kong X. Telocytes in human heart valves. J Cell Mol Med 2014;18(5):759–65.
  • 55. Zhang HQ, Lu SS, Xu T, Feng YL, Li H, Ge JB. Morphological evidence of telocytes in mice aorta. Chinese Med J 2015;128(3):348–52.
  • 56. Gherghiceanu M, Hinescu ME, Andrei F, Mandache E, Macarie CE, Faussone Pellegrini MS, et al. Interstitial Cajal-like cells (ICLC) in myocardial sleeves of human pulmonary veins. J Cell Mol Med 2008;12(5a):1777–81.
  • 57. Rusu MC, Jianu AM, Mirancea N, Didilescu AC, Manoiu VS, Paduraru D. Tracheal Telocytes. J Cell Mol Med 2012;16(2):401–5.
  • 58. Popescu BO, Gherghiceanu M, Kostin S, Ceafalan L, Popescu LM. Telocytes in meninges and choroid plexus. Neurosci Lett 2012;516(2):265–9.
  • 59. Chen X, Zheng Y, Manole CG, Wang X, Wang Q. Telocytes in human oesophagus. J Cell Mol Med 2013;17(11):1506–12.
  • 60. Karpus ON, Westendorp BF, Vermeulen JL, Meisner S, Koster J, Muncan V, et al. Colonic CD90+ Crypt fibroblasts secrete semaphorins to support epithelial growth. Cell Rep 2019;26(13):3708–968.
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  • 67. Li H, Zhang H, Yang L, Lu S, Ge J. Telocytes in mice bone marrow: electron microscope evidence. J Cell Mol Med 2014;18(6):975–8.
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Year 2020, Volume: 10 Issue: 2, 161 - 170, 01.08.2020

Özlem Delibaş , Serpil Ünver Saraydın

Abstract

References

  • 1. Hirst GDS, Ward SM. Interstitial cells: Involvement in rhythmicity and neural control of gut smooth muscle. J Physiol 2003;550(2):337–46.
  • 2. Faussone-Pellegrini MS. Ultrastructure of the tunica muscularis of the cardial portion of the human esophagus and stomach, with special reference to the so-called Cajal’s interstitial cells. Arch Ital Anat Embryol 1977;82(2):157–77.
  • 3. Thuneberg L. Interstitial cells of Cajal: intestinal pacemaker cells? Adv Anat Embryol Cell Biol 1982;71:1–130.
  • 4. Gabella G. Intestinal smooth muscle development. In Advances in the Innervation of the Gastrointestinal Tract. Elsevier Science Publishers; 1992. p.35–47.
  • 5. Torihashi S, Gerthoffer WT, Kobayashi S, Sanders KM. Identification and classification of interstitial cells in the canine proximal colon by ultrastructure and immunocytochemistry. Histochemistry 1994;101(3):169–83.
  • 6. Sanders KM, Koh SD, Ward SM. Interstitial cells of Cajal as pacemakers in the gastrointestinal tract. Annu Rev Physiol 2006;68:307–43.
  • 7. Forrest A, Huizinga JD, Wang XY, Liu LW, Parsons M. Increase in stretch-induced rhythmic motor activity in the diabetic rat colon is associated with loss of ICC of the submuscular plexus. Am J Physiol Gastrointest Liver Physiol 2008;294(1): G315–26.
  • 8. Lecoin L, Gabella G, Le Douarin N. Origin of the c-kitpositive interstitial cells in the avian bowel. Development 1996;122(3):725–33.
  • 9. Popescu LM, Hinescu M E, Ionescu N, Ciontea SM, Cretoiu D, Ardelean C. Interstitial cells of Cajal in pancreas. J Cell Mol Med 2005;9(1):169–90.
  • 10. Ciontea SM, Radu E, Regalia T, Ceafalan L, CretoiuD, Gherghiceanu M, et al. C-kit immunopositive interstitial cells (Cajal-type) in human myometrium. J Cell Mol Med 2005;9(2):407–20.
  • 11. Hutchings G, Williams O, Cretoiu D, Ciontea SM. Myometrial interstitial cells and the coordination of myometrial contractility. J Cell Mol Med 2009;13(10):4268–82.
  • 12. Popescu LM, Faussone-Pellegrini MS. TELOCYTES - a case of serendipity: the winding way from Interstitial Cells of Cajal (ICC), via Interstitial Cajal-Like Cells (ICLC) to TELOCYTES. J Cell Mol Med 2010;14(4):729–40.
  • 13. Popescu LM, Gherghiceanu M, Suciu LC, Manole CG, Hinescu ME. Telocytes and putative stem cells in the lungs: electron microscopy, electron tomography and laser scanning microscopy. Cell Tissue Res 2011;345(3):391–403.
  • 14. Cretoiu D, Cretoiu SM, Simionescu AA, Popescu LM. Telocytes, a distinct type of cell among the stromal cells present in the lamina propria of jejunum. Histol Histopathol 2012;27(8):1067–78.
  • 15. Cretoiu D. The Third Dimension of Telocytes Revealed by FIBSEM Tomography. In: Telocytes. Adv Exp Med Biol (Singapore) 2016;913:325–34.
  • 16. Faussone-Pellegrini MS, Gherghiceanu M. Telocyte’s contacts. Semin Cell Dev Biol 2016;55:3–8.
  • 17. Bassotti G, Villanacci V, Cretoiu D, Cretoiu SM, Becheanu G. Cellular and molecular basis of chronic constipation: taking the functional/idiopathic label out. World J Gastroenterol 2013;19(26):4099–105.
  • 18. Cretoiu SM, Popescu LM. Telocytes revisited. Biomolecular Concepts 2014;5(5):353–69.
  • 19. Popescu LM, Gherghiceanu M, Manole CG. FaussonePellegrini MS. Cardiac renewing: interstitial Cajal-like cells nurse cardiomyocyte progenitors in epicardial stem cell niches. J Cell Mol Med 2009;13(5):866–86.
  • 20. Gherghiceanu M, Popescu LM. Cardiomyocyte precursors and telocytes in epicardial stem cell niche: electron microscope images. J Cell Mol Med 2010;14(4):871–77.
  • 21. Luesma MJ, Gherghiceanu M, Popescu LM. Telocytes andstem cells in limbus and uvea of mouse eye. J Cell Mol Med 2013;17(8):1016–24.
  • 22. Gherghiceanu M, Manole CG, Popescu LM. Telocytes in endocardium: electron microscope evidence. J Cell Mol Med 2010;14(9):2330–4.
  • 23. Cantarero CI, Luesma BMJ, Junquera EC. Identification of telocytes in the lamina propria of rat duodenum: transmission electron microscopy. J Cell Mol Med 011;15(1):26–30.
  • 24. Cretoiu D, Radu BM, Banciu A, Banciu DD, Cretoiu SM. Telocytes heterogeneity: From cellular morphology to functional evidence. Semin Cell Dev Biol 2017;64:26–39.
  • 25. Zheng M, Sun X, Zhang M, Qian M, Zheng Y, Li M, et al. Variations of chromosomes 2 and 3 gene expression profiles among pulmonary telocytes, pneumocytes, airway cells, mesenchymal stem cells and lymphocytes. J Cell Mol Med 2014;18(10):2044–60.
  • 26. Song D, Cretoiu D, Zheng M, Qian M, Zhang M, Cretoiu SM, et al. Comparison of Chromosome 4 gene expression profile between lung telocytes and other local cell types. J Cell Mol Med 2016;20(1):71–80.
  • 27. Shoshkes-Carmel M, Wang YJ, Wangensteen KJ, Tóth B, Kondo A, Massasa EE, et al. Subepithelial telocytes are animportant source of Wnts that supports intestinal crypts. Nature 2018;557(7704):242–6.
  • 28. Cretoiu D, Vannucchi MG, Bei Y, Manetti M, FaussonePellegrini MS, Ibba-Manneschi L, et al. Telocytes: New Connecting Devices in the Stromal Space of Organs. In: Loewy Z, editor. Innovations in Cell Research and Therapy. London, UK: IntechOpen; 2019.
  • 29. Kucybala I, Janas P, Ciuk S, Cholopiak W, Klimek-Piotrowska W, Holda MK. A comprehensive guide to telocytes and their great potential in cardiovascular system. Bratislavske Lekarske Listy 2017;118(5):302–9.
  • 30. Popescu LM. The tandem: Telocytes-Stem cells. J Biol Biomed Eng 2011;5(2):83–92.
  • 31. Popescu LM, Ciontea SM, Cretoiu D. Interstitial Cajal-like cells in human uterus and fallopian tube. Ann N Y Acad Sci 2007;1101(1):139–65.
  • 32. Cretoiu D, Xu J, Xiao J, Cretoiu SM. Telocytes and their extracellular vesicles-Evidence and Hypotheses. Int J Mol Sci 2016;17(8):1322.
  • 33. Popescu LM, Manole CG, Gherghiceanu M, Ardelean A, Nicolescu MI, Hinescu ME, et al. Telocytes in human epicardium. J Cell Mol Med 2010;14(8):2085–93.
  • 34. Kostin S. Myocardial telocytes: a specific new cellular entity. J Cell Mol Med 2010;14(7):1917–21.
  • 35. Hinescu ME, Popescu LM. Interstitial Cajal-like cells (ICLC) in human atrial myocardium. J Cell Mol Med 2005;9(4):972–5.
  • 36. Cretoiu SM, Cretoiu D, Popescu LM. Human myometriumthe ultrastructural 3D network of telocytes. J Cell Mol Med 2012;16(11):2844–9.
  • 37. Vannucchi MG, Traini C, Manetti M, Ibba-Manneschi L, Faussone Pellegrini MS. Telocytes express PDGFRα in the human gastrointestinal tract. J Cell Mol Med 2013;17(9):1099–108.
  • 38. Corradi LS, Jesus MM, Fochi RA, Vilamaior PS, Justulin LA, Jr Góes RM, et al. Structural and ultrastructural evidence for telocytes in prostate stroma. J Cell Mol Med 2013;17(3):398–406.
  • 39. Hinescu ME, Gherghiceanu M, Mandache E, Ciontea SM, Popescu LM. Interstitial Cajal-like cells (ICLC) in atrial myocardium: ultrastructural and immunohistochemical characterization. J Cell Mol Med 2006;10(1):243–57.
  • 40. Shah S, Lubeck E, Zhou W, Cai L. seqFISH Accurately Detects Transcripts in Single Cells and Reveals Robust Spatial Organization in the Hippocampus. Neuron 2017;94(4):752–8.
  • 41. Kinchen J, Chen HH, Parikh K, Antanaviciute A, Jagielowicz M, Fawkner-Corbett D, et al. Structural remodeling of the human colonic mesenchyme in inflammatory bowel disease. Cell 2018;175(2):372–86.
  • 42. Bani D, Formigli L, Gherghiceanu M, Faussone-Pellegrini MS. Telocytes as supporting cells for myocardial tissue organization in developing and adult heart. J Cell Mol Med 2010;14(10):2531–8.
  • 43. Ceafalan L, Gherghiceanu M, Popescu LM, Simionescu O. Telocytes in human skin-are they involved in skin regeneration? J Cell Mol Med 2012;16(7):1405–20.
  • 44. Vannucchi MG, Traini C, Guasti D, Del Popolo G, FaussonePellegrini MS. Telocytes subtypes in human urinary bladder. J Cell Mol Med 2014;18(10):2000–8.
  • 45. Pieri L, Vannucchi MG, Faussone-Pellegrini MS. Histochemical and ultrastructural characteristics of an interstitial cell type different from ICC and resident in the muscle coat of human gut. J Cell Mol Med 2008;12(5b):1944–55.
  • 46. Dìaz-Flores L, Gutierrez R, Sáez FJ, Dìaz-Flores Jr L, Madrid JF. Telocytes in neuromuscular spindles. J Cell Mol Med 2013;17(4):457–65.
  • 47. Chaitow L. Telocytes: Connective tissue repair and communication cells. J Bodywork Mov Ther 2017;21(2):231–3.
  • 48. Gherghiceanu M, Popescu LM. Cardiac telocytes - their junctions and functional implications. Cell Tissue Res 2012;348(2):265–79.
  • 49. Fertig ET, Gherghiceanu M, Popescu LM. Extracellular vesicles release by cardiac telocytes: electron microscopy and electron tomography. J Cell Mol Med 2014;18(10):1938–43.
  • 50. Zhou J, Zhang Y, Wen X, Cao J, Li D, Lin Q, et al. Telocytes accompanying cardiomyocyte in primary culture: two- and threedimensional culture environment. J Cell Mol Med 2010;14(11):2641–5.
  • 51. Albulescu R, Tanase C, Codrici E, Popescu D, Cretoiu SM, Popescu LM. The secretome of myocardial telocytes modulates the activity of cardiac stem cells. J Cell Mol Med 2015;19(8):1783–94.
  • 52. Kang Y, Zhu Z, Zheng Y, Wan W, Manole CG, Zhang Q. Skin telocytes versus fibroblasts: two distinct dermal cell populations. J Cell Mol Med 2015;19(11):2530–9.
  • 53. Popescu LM, Manole E, Şerboiu CS, Manole CG, Suciu LC, Gherghiceanu M, et al. Identification of telocytes in skeletal muscle interstitium: implication for muscle regeneration. J Cell Mol Med 2011;15(6):1379–92.
  • 54. Yang Y, Sun W, Wu SM, Xiao J, Kong X. Telocytes in human heart valves. J Cell Mol Med 2014;18(5):759–65.
  • 55. Zhang HQ, Lu SS, Xu T, Feng YL, Li H, Ge JB. Morphological evidence of telocytes in mice aorta. Chinese Med J 2015;128(3):348–52.
  • 56. Gherghiceanu M, Hinescu ME, Andrei F, Mandache E, Macarie CE, Faussone Pellegrini MS, et al. Interstitial Cajal-like cells (ICLC) in myocardial sleeves of human pulmonary veins. J Cell Mol Med 2008;12(5a):1777–81.
  • 57. Rusu MC, Jianu AM, Mirancea N, Didilescu AC, Manoiu VS, Paduraru D. Tracheal Telocytes. J Cell Mol Med 2012;16(2):401–5.
  • 58. Popescu BO, Gherghiceanu M, Kostin S, Ceafalan L, Popescu LM. Telocytes in meninges and choroid plexus. Neurosci Lett 2012;516(2):265–9.
  • 59. Chen X, Zheng Y, Manole CG, Wang X, Wang Q. Telocytes in human oesophagus. J Cell Mol Med 2013;17(11):1506–12.
  • 60. Karpus ON, Westendorp BF, Vermeulen JL, Meisner S, Koster J, Muncan V, et al. Colonic CD90+ Crypt fibroblasts secrete semaphorins to support epithelial growth. Cell Rep 2019;26(13):3708–968.
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There are 72 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Collection
Authors

Özlem Delibaş

Serpil Ünver Saraydın This is me

Publication Date August 1, 2020
Published in Issue Year 2020 Volume: 10 Issue: 2

Cite

APA Delibaş, Ö., & Ünver Saraydın, S. (2020). Telositlerin Morfolojisi ve Fonksiyonları. Kafkas Journal of Medical Sciences, 10(2), 161-170.
AMA Delibaş Ö, Ünver Saraydın S. Telositlerin Morfolojisi ve Fonksiyonları. KAFKAS TIP BİL DERG. August 2020;10(2):161-170.
Chicago Delibaş, Özlem, and Serpil Ünver Saraydın. “Telositlerin Morfolojisi Ve Fonksiyonları”. Kafkas Journal of Medical Sciences 10, no. 2 (August 2020): 161-70.
EndNote Delibaş Ö, Ünver Saraydın S (August 1, 2020) Telositlerin Morfolojisi ve Fonksiyonları. Kafkas Journal of Medical Sciences 10 2 161–170.
IEEE Ö. Delibaş and S. Ünver Saraydın, “Telositlerin Morfolojisi ve Fonksiyonları”, KAFKAS TIP BİL DERG, vol. 10, no. 2, pp. 161–170, 2020.
ISNAD Delibaş, Özlem - Ünver Saraydın, Serpil. “Telositlerin Morfolojisi Ve Fonksiyonları”. Kafkas Journal of Medical Sciences 10/2 (August 2020), 161-170.
JAMA Delibaş Ö, Ünver Saraydın S. Telositlerin Morfolojisi ve Fonksiyonları. KAFKAS TIP BİL DERG. 2020;10:161–170.
MLA Delibaş, Özlem and Serpil Ünver Saraydın. “Telositlerin Morfolojisi Ve Fonksiyonları”. Kafkas Journal of Medical Sciences, vol. 10, no. 2, 2020, pp. 161-70.
Vancouver Delibaş Ö, Ünver Saraydın S. Telositlerin Morfolojisi ve Fonksiyonları. KAFKAS TIP BİL DERG. 2020;10(2):161-70.
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