kujes

Kastamonu University Journal of Engineering and Sciences

2667-8209

Kastamonu University

Instrumental Methods

Enstrümantal Yöntemler

Adli Analizde Malathion ve 4F-MDMB-BUTICA'nın Eşzamanlı Tanımlanması için GC-MS Uygulaması

Application of GC-MS for Simultaneous Identification of Malathion and 4F-MDMB-BUTICA in Forensic Analysis

https://orcid.org/0000-0002-5807-3494

Gökmeşe

Ebru

HİTİT ÜNİVERSİTESİ

https://orcid.org/0009-0007-4608-9599

Küyük

Melike

JANDARMA VE SAHİL GÜVENLİK AKADEMİSİ, JANDARMA VE SAHİL GÜVENLİK FAKÜLTESİ

https://orcid.org/0000-0002-0275-3941

Gokmeşe

Faruk

HİTİT ÜNİVERSİTESİ

12 25 2025

11 2 96 103 11 19 2025 12 16 2025

2015

Kastamonu University Journal of Engineering and Sciences

Sentetik kannabinoidler, doğal esrarın (THC) etkilerini taklit etmek üzere geliştirilmiş kimyasallar olup, THC’den çok daha güçlü ve tehlikelidirler. Bu tip maddeler “bonzai” gibi isimler ile bilinen bitkisel karışımlara püskürtülerek yasa dışı uyuşturucu pazarına sürülür. Malathion, tarımda zararlıların yok edilmesi ve kontrolü için kullanılan organofosforlu (OP) bir insektisittir. İnsanlar için düşük toksisitede bile malathiona maruz kalmanın solunum yolları ve sinir sistemi üzerinde olumsuz etkileri vardır. Bu çalışmada, sedatif etkiye sahip sentetik kannabinoidler ile birlikte kullanılan tarım ilacı kalıntılarının numunelerde eş zamanlı tespit edilmesine yönelik bir GC-MS metodu geliştirilmiştir. Organofosfatlı insektisitlerden Malathion ve yeni nesil sentetik kannabinoidlerden 4-Fluoro-MDMB-BUTICA, bitkisel numuneler üzerinde kalitatif olarak analiz edilmiştir. Elde edilen veriler neticesinde sedatif etkide bitkisel otların içerisine emdirilen Malathion tarım ilacı tespit edilerek analizine olanak sağlanacaktır. Bu çalışmada tarım ilaçlarının kalitatif analizi, Gaz Kromatografi-Kütle Spektrometresi (GC-MS) cihazı ile optimize edilen deney metodu kullanılarak yapılmıştır.

Synthetic cannabinoids are chemicals developed to mimic the effects of natural marijuana (THC), and they are much more powerful and dangerous than THC. These types of substances are sprayed into herbal mixtures known as "bonzai" and put into the illegal drug market. Malathion is an organophosphorus (OP) insecticide used for the destruction and control of pests in agriculture. Even with low toxicity to humans, exposure to malathion has adverse effects on the respiratory tract and nervous system. In this study, a GC-MS method was developed for the simultaneous detection of pesticide residues used with synthetic cannabinoids with sedative effects in samples. Malathion, an organophosphate insecticide, and 4-Fluoro-MDMB-BUTICA, a new generation synthetic cannabinoid, were qualitatively analyzed on plant samples. As a result of the data obtained, Malathion pesticide, which has a sedative effect and is absorbed into herbs, will be detected and analyzed. In this study, qualitative analysis of pesticides was performed using the experimental method optimized with the Gas Chromatography-Mass Spectrometry (GC-MS) device.

Malathion Cannabinoid Forensic Analysis GC-MS

Malathion kanabinoid Adli Analiz GC-MS

Gendarmerie Criminal Directorate, Central Laboratory

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