By determining the change of land use characteristics over the years, changes in urban growth and land use can be revealed. Monitoring of the change in the land cover allows for better protection of forest areas as well as efficient agricultural areas and regular urbanization. Corine System is one of the commonly used methods for the determination of land use. This system established by the European Union countries, is used by Turkey. In this study, using the Corine System, changes in urban growth and land use in Mersin province between 1990-2018 were determined. Based on the Corine System, simplification was made in the classification. Thus, the change in the land was tried to be revealed more clearly. The changes in land cover in Mersin province have been tried to be presented based on 15 classes considering 1990, 2000 and 2018. Within the scope of the study, the reasons and consequences of the changes occurring in these periods are emphasized. As a result, the changes occurring in the 28 years in the land cover examined in 3 periods are presented within the frame of visual and measurement values. It has been observed that residential areas in Mersin are getting bigger and bigger. Planning for the future in Mersin should be made by considering these changes in land cover.