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Trombofili ve Şiddetli Preeklampsi; Vaka Sunumu ve Literatür İncelemesi

Year 2014, Volume: 15 Issue: 2, - , 01.08.2014

Abstract

Preeclampsia occurs in 3- 14 % of pregnancies and is one of the major causes of maternal and fetal morbidity and mortality. Congenital or acquired trombophilia may play an important role in the pathology of preeclampsia because preeclampsia accompanies with endothelial damage and coagulation problems. In this case report, we aimed to interpret the current literature, the relationship between severe preeclampsia and thrombophilia, and their effects on pregnancy outcomes

References

  • Cudihy D, Lee RV. The pathophysiology of pre- eclampsia: current clinical concepts. J Obstet Gynaecol 2009;29(7):576-82.
  • ACOG practice bulletin. Diagnosis and management of preeclampsia and eclampsia. Number 33, January 200 American College of Obstetricians and Gynecologists. Int J Gynaecol Obstet 2002;77(1):67
  • Dekker GA, de Vries JI, Doelitzsch PM, et al. Underlying disorders associated with severe early- onset 1995;173(4):1042-8. Am preeclampsia. J Obstet Gynecol
  • Greer IA. Thrombophilia: implications for pregnancy outcome. Thromb Res 2003;109(2- 3):73
  • Verspyck E, Borg JY, Le Cam-Duchez V, et al. Thrombophilia and fetal growth restriction. Eur J Obstet Gynecol Reprod Biol 2004;113(1):36-40.
  • Brenner B. Thrombophilia and adverse pregnancy outcome. 2006;33(3):443-56. Gynecol Obstet Clin North Am mutation complications: a systematic review and meta-analysis of 2010;7(6):e1000292. pregnancy cohort studies. PLoS Med 187 Simavlı ve İşler
  • Said JM, Higgins JR, Moses EK, Walker SP, Monagle PT, Brennecke SP. Inherited thrombophilias and adverse pregnancy outcomes: a case-control study in an Australian population. Acta Obstet Gynecol Scand 2012;91(2):250-5.
  • Robertson L, Wu O, Langhorne P, et al. Thrombophilia in pregnancy: a systematic review. Br J Haematol 2006;132(2):171-96.
  • Said JM, Higgins JR, Moses EK, et al. Inherited thrombophilia outcomes in nulliparous women. Obstet Gynecol 2010;115(1):5-13. and pregnancy
  • Silver RM, Zhao Y, Spong CY, et al. Prothrombin gene G20210A mutation and obstetric complications. Obstet Gynecol 2010;115(1):14-20.
  • Deveer R, Engin-Ustun Y, Akbaba E, et al. Association between Pre-eclampsia and inherited thrombophilias. Fetal Pediatr Pathol 2013;32(3):213
  • Kjellberg U, van Rooijen M, Bremme K, Hellgren M. Factor V Leiden mutation and pregnancy-related complications. 2010;203(5):469.e1-8. J Obstet Gynecol
  • Arias F, Romero R, Joist H, Kraus FT. Thrombophilia: a mechanism of disease in women with adverse pregnancy outcome and thrombotic lesions in the placenta. J Matern Fetal Med 1998;7(6):277-86.
  • Dudding TE, Attia J. The association between adverse pregnancy outcomes and maternal factor V Leiden genotype: a meta-analysis. Thromb Haemost 2004;91(4):700-11.

Trombofili ve Şiddetli Preeklampsi; Vaka Sunumu ve Literatür İncelemesi

Year 2014, Volume: 15 Issue: 2, - , 01.08.2014

Abstract

Preeklampsi, insan gebeliklerinin yaklaşık % 3- 14’ünü komplike eden, maternal ve fetal mortalite ve morbiditenin en önemli nedenlerindendir. Preeklampsi, endotelyal hasar ve koagulasyon problemleriyle birlikte olabildiğinden, konjenital veya kazanılmış trombofili bu patolojide önemli bir rol oynayabilir. Bu olguda trombofili ile şiddetli preeklampsi ilişkisini ve bu ilişkinin gebelik sonuçlarına olan etkisini güncel literatür ışığında yorumlamayı amaçladık

References

  • Cudihy D, Lee RV. The pathophysiology of pre- eclampsia: current clinical concepts. J Obstet Gynaecol 2009;29(7):576-82.
  • ACOG practice bulletin. Diagnosis and management of preeclampsia and eclampsia. Number 33, January 200 American College of Obstetricians and Gynecologists. Int J Gynaecol Obstet 2002;77(1):67
  • Dekker GA, de Vries JI, Doelitzsch PM, et al. Underlying disorders associated with severe early- onset 1995;173(4):1042-8. Am preeclampsia. J Obstet Gynecol
  • Greer IA. Thrombophilia: implications for pregnancy outcome. Thromb Res 2003;109(2- 3):73
  • Verspyck E, Borg JY, Le Cam-Duchez V, et al. Thrombophilia and fetal growth restriction. Eur J Obstet Gynecol Reprod Biol 2004;113(1):36-40.
  • Brenner B. Thrombophilia and adverse pregnancy outcome. 2006;33(3):443-56. Gynecol Obstet Clin North Am mutation complications: a systematic review and meta-analysis of 2010;7(6):e1000292. pregnancy cohort studies. PLoS Med 187 Simavlı ve İşler
  • Said JM, Higgins JR, Moses EK, Walker SP, Monagle PT, Brennecke SP. Inherited thrombophilias and adverse pregnancy outcomes: a case-control study in an Australian population. Acta Obstet Gynecol Scand 2012;91(2):250-5.
  • Robertson L, Wu O, Langhorne P, et al. Thrombophilia in pregnancy: a systematic review. Br J Haematol 2006;132(2):171-96.
  • Said JM, Higgins JR, Moses EK, et al. Inherited thrombophilia outcomes in nulliparous women. Obstet Gynecol 2010;115(1):5-13. and pregnancy
  • Silver RM, Zhao Y, Spong CY, et al. Prothrombin gene G20210A mutation and obstetric complications. Obstet Gynecol 2010;115(1):14-20.
  • Deveer R, Engin-Ustun Y, Akbaba E, et al. Association between Pre-eclampsia and inherited thrombophilias. Fetal Pediatr Pathol 2013;32(3):213
  • Kjellberg U, van Rooijen M, Bremme K, Hellgren M. Factor V Leiden mutation and pregnancy-related complications. 2010;203(5):469.e1-8. J Obstet Gynecol
  • Arias F, Romero R, Joist H, Kraus FT. Thrombophilia: a mechanism of disease in women with adverse pregnancy outcome and thrombotic lesions in the placenta. J Matern Fetal Med 1998;7(6):277-86.
  • Dudding TE, Attia J. The association between adverse pregnancy outcomes and maternal factor V Leiden genotype: a meta-analysis. Thromb Haemost 2004;91(4):700-11.
There are 14 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Serap Simavlı This is me

Cevdet İşler This is me

Publication Date August 1, 2014
Published in Issue Year 2014 Volume: 15 Issue: 2

Cite

APA Simavlı, S., & İşler, C. (2014). Trombofili ve Şiddetli Preeklampsi; Vaka Sunumu ve Literatür İncelemesi. Kocatepe Tıp Dergisi, 15(2). https://doi.org/10.18229/ktd.89249
AMA Simavlı S, İşler C. Trombofili ve Şiddetli Preeklampsi; Vaka Sunumu ve Literatür İncelemesi. KTD. August 2014;15(2). doi:10.18229/ktd.89249
Chicago Simavlı, Serap, and Cevdet İşler. “Trombofili Ve Şiddetli Preeklampsi; Vaka Sunumu Ve Literatür İncelemesi”. Kocatepe Tıp Dergisi 15, no. 2 (August 2014). https://doi.org/10.18229/ktd.89249.
EndNote Simavlı S, İşler C (August 1, 2014) Trombofili ve Şiddetli Preeklampsi; Vaka Sunumu ve Literatür İncelemesi. Kocatepe Tıp Dergisi 15 2
IEEE S. Simavlı and C. İşler, “Trombofili ve Şiddetli Preeklampsi; Vaka Sunumu ve Literatür İncelemesi”, KTD, vol. 15, no. 2, 2014, doi: 10.18229/ktd.89249.
ISNAD Simavlı, Serap - İşler, Cevdet. “Trombofili Ve Şiddetli Preeklampsi; Vaka Sunumu Ve Literatür İncelemesi”. Kocatepe Tıp Dergisi 15/2 (August 2014). https://doi.org/10.18229/ktd.89249.
JAMA Simavlı S, İşler C. Trombofili ve Şiddetli Preeklampsi; Vaka Sunumu ve Literatür İncelemesi. KTD. 2014;15. doi:10.18229/ktd.89249.
MLA Simavlı, Serap and Cevdet İşler. “Trombofili Ve Şiddetli Preeklampsi; Vaka Sunumu Ve Literatür İncelemesi”. Kocatepe Tıp Dergisi, vol. 15, no. 2, 2014, doi:10.18229/ktd.89249.
Vancouver Simavlı S, İşler C. Trombofili ve Şiddetli Preeklampsi; Vaka Sunumu ve Literatür İncelemesi. KTD. 2014;15(2).

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