Kore Benzeri Klinik Bulgular ve Epilepsinin Eşlik Ettiği Bilateral Striopallidodentat Kalsinosis: Olgu Sunumu

Year 2009, Volume: 10 Issue: 1, 13 - 16, 01.04.2009

Özge Yılmaz-küsbeci Mehmet Yaman Alpay Haktanır Aylin Yücel

Abstract

Bilateral striatopallidodentat kalsinozisle (BSPDK) nadir görülen, çeşitli semptomların bir arada görülebildiği ve bazal ganglionlar, serebellum ve serebral beyaz cevherde kalsiyum ve diğer minerallerin birikmesi ile karakterize bir hastalıktır. Genellikle idyopatik olarak görülmekle birlikte hipoparatiroidizm ve hipokalsemi birlikteliği, en sık görülen sekonder BSPDK nedenidir. Bu çalışmada hipoparatiroidizme bağlı olarak BSPDK saptanan ve hipokalsemi tablosunun düzeltilmesi ile klinik olarak belirgin iyileşme gösteren bir vaka sunulacaktır

Keywords

Striopallidodental kalsinosis, hipokalsemi, hipoparatiroidizm

Kore Benzeri Klinik Bulgular ve Epilepsinin Eşlik Ettiği Bilateral Striopallidodentat Kalsinosis: Olgu Sunumu

Abstract

Keywords

-

References

• Manyam BV. What is and what is ot ‘Fahr’s disease’. Parkinsonism and Relat Disord 2005;11:73-80
• Hanağası H, Hanağası F, Bilgiç B, ve ark. Bilateral striopallidodentat kalsinosis’in klinik spektrumu. Türk Nöroloji Dergisi 2004; 5: 430-7.
• Uslu Fİ, Hanağası HA. Hipoparatroidizm ve Bilateral Striopallidodentat Kalsinozis. Nöropsikiyatri Arşivi, 2006; 43: 31-36.
• Malik R, Pandya VK, Naik D. Fahr disease. A rare neurodegenerative disorder. Ind J Radiol Imag, 2004;14:383-384
• Avrahmi E, Cohn DF, Feibel M, Tadmor R. MRI demonstration and CT correlation of the brain in patients with idiopathic intracerebral calcification. J Neurol 1994;241:381-384.
• Modrego PJ, Mojonero J, Serrano M, Fayed N. Fahr’s syndrome presenting with pure and progresive presenile demantia. Neurol Sci 2005;26:367-369.
• Windeck R, Menken U. Basal ganglia calcification in pseudohypoparathyroidism typeII. Clin Endocrinol, 1981;15:57-63.
• Morgante L, Vita G. Di Perri R. Fahr’s syndrome: local inflammatory factors in the pathogenesis of calcification. J Neurol 1986;233:19-22.
• Anderson J.R. Intracerebral calcifications in a case of SLE with neurologic manifestations. Neuroradiology 1980;19:213-214.
• Duckett S, Galle P, Escourolle R, Poirier J, Hauw JJ. Presence of zinc, aluminum, magnesium in striopallidodentate (SPD)calcifications (Fahr’s disease): electron probe study. Acta Neuropathol (Berl) 1977;38:7–10.
• Kozik M, Kulczycki J. Laser-spectrographic analysis of the cation content in Fahr’s syndrome. Arch Psychiatr Nervenkr 1978;225: 135–42.
• Kobayashi S, Yamadori I, Miki H, Ohmori M. Idiopathic nonarteriosclerotic cerebral calcification (Fahr’s disease): an electron microscopic study. Acta Neuropathol (Berl) 1987;73:62–6.
• Manyam BV, Walters AS, Keller IA, Ghobrial M. Parkinsonism associated with autosomal dominant bilateral striopallidodentate calcinosis. Parkinsonism Relat Disord 2001;7:289–95.
• Stelmasiak Z, Tarach JS, Nowicka- Tarach, BM, Mitosek- Szewczyk K, Drop A. Idiopatic hypoparathyroidism with intracranial calcification and dominant skin manifestions. Med Sci Monit 2000; 6; 145-50.
• Paprocka J, Jamroz E, Wackermann-Ramos A, Sokol M, Marszal E. [Neurological picture and 1H MRS in 4 children with hypoparathyroidism] Przegl Lek. 2005; 62: 680-4.
• Karimi M, Habibzadeh F, De Sanctis V. Hypoparathyroidism with extensive intracerebral calcification in patients with beta-thalassemia major. J Pediatr Endocrinol Metab 203;16:883-886